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Results for "

PEPCK

" in MedChemExpress (MCE) Product Catalog:

5

Inhibitors & Agonists

2

Natural
Products

1

Recombinant Proteins

1

Antibodies

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-123046
    AS1708727
    3 Publications Verification

    		 Autophagy Metabolic Disease Cancer
    AS1708727 is an orally active Foxo1 inhibitor, with EC50 values of 0.33 μM and 0.59 μM for G6Pase and PEPCK, respectively .
    AS1708727
  • HY-111896
    7-Methoxyrosmanol

    7-O-Methoxyrosmanol

    		 PEPCK Others
    7-Methoxyrosmanol (7-O-Methoxyrosmanol), a phenolic diterpene isolated from rosemary, suppresses the cAMP responsiveness of PEPCK and G6Pase promoters .
    7-Methoxyrosmanol
  • HY-128923
    SKF-34288 hydrochloride
    4 Publications Verification

    3-Mercaptopicolinic acid hydrochloride; 3-MPA hydrochloride

    		 PEPCK Metabolic Disease
    SKF-34288 (3-Mercaptopicolinic acid) hydrochloride is an orally active phosphoenolpyruvate carboxykinase (PEPCK) inhibitor (Ki: 2-9 μM). SKF-34288 hydrochloride is a potent hypoglycemic agent by inhibiting glucose synthesis. SKF-34288 hydrochloride also inhibits Asn metabolism and increases amino acids and amides .
    SKF-34288 hydrochloride
  • HY-153347
    JY-2
    1 Publications Verification

    		 FOXO Metabolic Disease
    JY-2 is a moderately selective and orally active Forkhead transcription factor forkhead box O1 (FoxO1) inhibitor that inhibits FoxO1 transcriptional activity with an IC50 of 22 μM. JY-2 shows moderate inhibition against FoxO3a and FoxO4. JY-2 shows anti-diabetic activity .
    JY-2
  • HY-N3720
    Demethoxycapillarisin

    6-Demethoxycapillarisin

    		 PEPCK Metabolic Disease
    Demethoxycapillarisin (6-Demethoxycapillarisin) inhibits PEPCK mRNA levels (IC50: 43 μM) by activation of the PI3K pathway. Demethoxycapillarisin decreases glucose production .
    Demethoxycapillarisin

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