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Results for "

PGRMC1

" in MedChemExpress (MCE) Product Catalog:

3

Inhibitors & Agonists

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-RS10399
    PGRMC1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    PGRMC1 Human Pre-designed siRNA Set A contains three designed siRNAs for PGRMC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    PGRMC1 Human Pre-designed siRNA Set A
    PGRMC1 Human Pre-designed siRNA Set A
  • HY-121012
    (rac)-AG-205

    		NF-κB Akt Endocrinology
    (rac)-AG-205 is a potent inhibitor of progesterone receptor membrane component 1 (Pgrmc1) that induces genes involved in sterol synthesis, including the INSIG1 protein, which forms a complex with PGRMC1. (rac)-AG-205 prevents neuronal resistance to hypoxic ischaemia by blocking NF-kB signalling and activation of the BDNF/PI3K/AKT pathway [1].
    (rac)-AG-205
  • HY-115625
    AG-205

    		Progesterone Receptor Apoptosis Cancer
    AG-205 is a progesterone receptor membrane component-1 (PGRMC1) inhibitor with anti-mitotic, anti-migratory and anti-invasive activities. AG-205 increases expression of genes coding enzymes of the cholesterol biosynthetic pathway or of steroidogenesis. AG-205 promotes Apoptosis modified regulation of the cell cycle and reduces cell migration and invasion capacities in ovary and breast cancer cells [1].
    AG-205

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