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Pathways Recommended: PROTAC
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PROTAC SMARCA2/4-degrader-25

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-162813
    PROTAC SMARCA2/4-degrader-25

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC SMARCA2/4-degrader-25 is a PROTAC targeting SMARCA2/4. PROTAC SMARCA2/4-degrader-25 is composed of E3 ligase (2S,4R)-4-Hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (HY-W998248), PROTAC Linker (S)-2-Amino-3,3-dimethylbutanoic acid (HY-59140), and target protein ligand SMARCA2/4-ligand-3 (HY-162814), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC (HY-125845) .
    PROTAC SMARCA2/4-degrader-25
  • HY-162815
    PROTAC SMARCA2/4-degrader-26

    		PROTACs Epigenetic Reader Domain Cancer
    PROTAC SMARCA2/4-degrader-26 is a PROTAC targeting SMARCA2/4. PROTAC SMARCA2/4-degrader-25 is composed of PROTAC target protein ligand 2-(4-(3-Amino-6-(2-hydroxyphenyl)pyridazin-4-yl)piperazin-1-yl)acetic acid (HY-46618), E3 ligase (2S,4R)-4-Hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (HY-W998248), and PROTAC linker (S)-2-Amino-3,3-dimethylbutanoic acid (HY-59140), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC (HY-125845) .
    PROTAC SMARCA2/4-degrader-26

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