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Results for "

Paris

" in MedChemExpress (MCE) Product Catalog:

15

Inhibitors & Agonists

14

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N3584
    Paris saponin VII
    2 Publications Verification

    Chonglou Saponin VII

    		 Akt p38 MAPK P-glycoprotein Bcl-2 Family Caspase PARP Autophagy Apoptosis Cancer
    Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
    Paris saponin VII
  • HY-N0047
    Polyphyllin I
    1 Publications Verification

    		 JNK mTOR Akt PDK-1 Autophagy Apoptosis Cancer
    Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .
    Polyphyllin I
  • HY-N3584R
    Paris saponin VII (Standard)

    		Akt p38 MAPK P-glycoprotein Bcl-2 Family Caspase PARP Autophagy Apoptosis Cancer
    Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
    Paris saponin VII (Standard)
  • HY-N12065
    Parisyunnanoside H

    		Others Others
    Parisyunnanoside H is a steroidal saponin isolated from Paris polyphylla Smith var. yunnanensis .
    Parisyunnanoside H
  • HY-N8814
    Parisyunnanoside B

    		Others Others
    Parisyunnanoside B is a Steroids product that can be isolated from the rhizomes of Paris yunnanensis Franch. .
    Parisyunnanoside B
  • HY-W019830
    Polyphyllin F

    		Others Others
    Polyphyllin F is a diosgenyl saponin that can be found in Paris polyphylla .
    Polyphyllin F
  • HY-N0047R
    Polyphyllin I (Standard)

    		JNK mTOR Akt PDK-1 Autophagy Apoptosis Cancer
    Polyphyllin I (Standard) is the analytical standard of Polyphyllin I. This product is intended for research and analytical applications. Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .
    Polyphyllin I (Standard)
  • HY-N12002
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside

    		Others Others
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside (compound 9) is a steroidal saponin, which can be obtained from Paris polyphylla var., Yunnan pine (yunnanensis) Isolated .
    Diosgenin-3-O-rhamnosyl(1→2)[glucosyl(1→6)]glucoside
  • HY-16958R
    PD 404182 (Standard)

    		Antibiotic Inflammation/Immunology
    Paris saponin VII (Standard) is the analytical standard of Paris saponin VII. This product is intended for research and analytical applications. Paris saponin VII (Chonglou Saponin VII) is a steroidal saponin isolated from the roots and rhizomes of Trillium tschonoskii. Paris saponin VII-induced apoptosis in K562/ADR cells is associated with Akt/MAPK and the inhibition of P-gp. Paris saponin VII attenuates mitochondrial membrane potential, increases the expression of apoptosis-related proteins, such as Bax and cytochrome c, and decreases the protein expression levels of Bcl-2, caspase-9, caspase-3, PARP-1, and p-Akt. Paris saponin VII induces a robust autophagy in K562/ADR cells and provides a biochemical basis in the treatment of leukemia .
    PD 404182 (Standard)
  • HY-N2386
    Polyphyllin E

    		Others Others
    Polyphyllin E is a steroidal saponin that can be isolated from Paris polyphylla .
    Polyphyllin E
  • HY-N2389
    Formosanin C
    2 Publications Verification

    		 Apoptosis Cancer
    Formosanin C is a diosgenin saponin isolated from Paris polyphylla and an immunomodulator with antitumor activity. Formosanin C induces apoptosis .
    Formosanin C
  • HY-N2389R
    Formosanin C (Standard)

    		Apoptosis Cancer
    Formosanin C (Standard) is the analytical standard of Formosanin C. This product is intended for research and analytical applications. Formosanin C is a diosgenin saponin isolated from Paris polyphylla and an immunomodulator with antitumor activity. Formosanin C induces apoptosis .
    Formosanin C (Standard)
  • HY-N4180
    Pennogenin 3-O-beta-chacotrioside

    		Atg8/LC3 Autophagy Cancer
    Pennogenin 3-O-beta-chacotrioside is an active component isolated from Paris polyphylla, modulates autophagy via increasing the expressions of autophagy-related proteins LC3 and Beclin-1. Anti-colorectal cancer activity .
    Pennogenin 3-O-beta-chacotrioside
  • HY-N0817
    Polyphyllin G

    		Apoptosis Autophagy Bacterial Inflammation/Immunology Cancer
    Polyphyllin G is isolated from the rhizomes of Paris yunnanensis, with antimicrobial and anticancer activity. Polyphyllin G prevents the growth of both Gram-positive and Gram-negative bacteria with minimum inhibitory concentrations (MICs) . Polyphyllin G induces apoptosis dependent on the activations of caspase-8, -3, and -9, induces autophagy .
    Polyphyllin G
  • HY-W015590R
    2-Hydroxyphenylacetic acid (Standard)

    		Endogenous Metabolite Neurological Disease
    Polyphyllin I (Standard) is the analytical standard of Polyphyllin I. This product is intended for research and analytical applications. Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis .
    2-Hydroxyphenylacetic acid (Standard)

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