2. MAPK/ERK Pathway PI3K/Akt/mTOR Autophagy Apoptosis
  3. JNK mTOR Akt PDK-1 Autophagy Apoptosis
  4. Polyphyllin I (Standard)

Polyphyllin I (Standard) 

Cat. No.: HY-N0047R Purity: ≥98%
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Polyphyllin I (Standard) is the analytical standard of Polyphyllin I. This product is intended for research and analytical applications. Polyphyllin I is a bioactive constituent extracted from Paris polyphylla, has strong anti-tumor activity. Polyphyllin I is an activator of the JNK signaling pathway and is an inhibitor of PDK1/Akt/mTOR signaling. Polyphyllin I induces autophagy, G2/M phase arrest and apoptosis.

For research use only. We do not sell to patients.

Polyphyllin I (Standard) Chemical Structure

Polyphyllin I (Standard) Chemical Structure

CAS No. : 50773-41-6

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Description
Molecular Weight

855.02

Formula

C44H70O16
CAS No.
SMILES

C[C@H](CC1)CO[C@]21O[C@@]3([H])C[C@@]4([H])[C@@]5([H])[C@]([C@](CC[C@H](O[C@]6([H])O[C@H](CO)[C@@H](O[C@]7([H])O[C@@H](CO)[C@H](O)[C@H]7O)[C@H](O)[C@H]6O[C@@]8([H])[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O8)C9)(C)C9=CC5)([H])CC[C@]4(C)[C@@]3([H])[C@@H]2C
Structure Classification
Initial Source
Storage

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Purity & Documentation
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Polyphyllin I (Standard) Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Polyphyllin I (Standard)50773-41-6JNKmTORAktPDK-1AutophagyApoptosisc-Jun N-terminal kinaseMammalian target of RapamycinPKBProtein kinase B3-Phosphoinositide-dependent protein kinase 1Paris polyphyllaanti-tumorPDK1/Akt/mTOR signalingG2/M phaseInhibitorinhibitorinhibit

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