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Polygalaceae

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) GABA Receptor (1) Influenza Virus (1)
By Research Areas:	Infection (1) Neurological Disease (3)

8

Inhibitors & Agonists

7

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

(E)-3,4,5-Trimethoxycinnamic acid TMCA	GABA Receptor 5-HT Receptor	Neurological Disease
(E)-3,4,5-Trimethoxycinnamic acid (TMCA) is a cinnamic acid substituted by multi-methoxy groups. (E)-3,4,5-Trimethoxycinnamic acid is an orally active and potent GABA_A/BZ receptor agonist. (E)-3,4,5-Trimethoxycinnamic exhibits favourable binding affinity to 5-HT_2C and 5-HT_1A receptor, with IC₅₀ values of 2.5 and 7.6 μM, respectively. (E)-3,4,5-Trimethoxycinnamic acid shows anticonvulsant and sedative activity. (E)-3,4,5-Trimethoxycinnamic acid can be used for the research of insomnia, headache and epilepsy .

Polygalasaponin XXXI Onjisaponin F	Influenza Virus	Infection
Polygalasaponin XXXI (Onjisaponin F) is an effective adjuvant for intranasal administration of influenza Influenza hemagglutinin (HA) vaccine to protect influenza virus infection .

Rhamnetin 3-O-β-D-glucopyranoside	Others	Others
Rhamnetin 3-O-β-D-glucopyranoside is a flavonoid, that can be isolated from the roots of Polygala sibirica L. (Polygalaceae) .

Tenuifoliose C	Others	Neurological Disease
Tenuifoliose C is an oligosaccharide that can be isolated from Polygala tenuifolia, used in neural-related research .

Tenuifoliose K	Others	Others
Tenuifoliose K is an oligosaccharide and can be isolated from Polygala tenuifolia .

Tenuifoliose D	Others	Others
Tenuifoliose D is an oligosaccharide and can be isolated from Polygala tenuifolia .

Tenuifoliose B	Others	Neurological Disease
Tenuifoliose B is an oligosaccharide and can be isolated from Polygala tenuifolia. Tenuifoliose B exhibits neuroprotective activity against glutamate and serum deficiency .

Fallaxsaponin A	Others	Others
Fallaxsaponin A (compound 5) is a natural product isolated from Polygala root .

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