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Results for "

R-110

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

1

Fluorescent Dye

3

Peptides

1

Inhibitory Antibodies

1

Antibodies

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-115887
    R110

    		Macrophage migration inhibitory factor (MIF) Cancer
    R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases .
    R110
  • HY-P99496
    Cendakimab

    RPC 4046; ABT 308; CC-93538

    		 Interleukin Related Inflammation/Immunology
    Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC50s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis) .
    Cendakimab
  • HY-D1311
    R110 azide, 6-isomer

    		Fluorescent Dye
    R110 azide, 6-isomer is an isomer of rhodamine dye with an azide group that labels DNA fragments. It enables visualization of the results of capillary electrophoresis genotyping experiments and gel shift experiments.
    R110 azide, 6-isomer
  • HY-P10322
    Z-IETD-R110

    		Fluorescent Dye Cancer
    Z-IETD-R110 is a fluorescent substrate of caspases. Z-IETD-R110 acts as a substrate for caspase-8. When caspase-8 is activated, it can recognize and cut Z-IETD-R110, releasing fluorophore, which can be detected by fluorescence microscopy. Z-IETD-R110 can be used to study oxidative stress-induced apoptosis, particularly in pancreatic acinar cells .
    Z-IETD-R110
  • HY-D1709
    Z-AA-R110-PEG

    		Biochemical Assay Reagents Others
    Z-AA-R110-PEG is a substrate for elastate.
    Z-AA-R110-PEG
  • HY-P4403
    Z-DEVD-R110

    (Z-Asp-Glu-Val-Asp)₂-Rhodamine 110

    		 Fluorescent Dye Apoptosis Caspase Others
    Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore .
    Z-DEVD-R110
  • HY-P10454
    (Z-IETD)2-Rh 110

    (Z-Ile-Glu-Thr-Asp)2-R110

    		 Caspase Others
    (Z-IETD)2-Rh 110 is a fluorescent substrate of caspase-8 (λex= 488 nm, λem= 523 nm), which can be used to detect the activity of caspase-8 and the process of apoptosis .
    (Z-IETD)2-Rh 110

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