2. Immunology/Inflammation
  3. Macrophage migration inhibitory factor (MIF)
  4. R110

R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases.

For research use only. We do not sell to patients.

R110 Chemical Structure

R110 Chemical Structure

CAS No. : 1985622-33-0

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 396 In-stock
Solution
10 mM * 1 mL in DMSO USD 396 In-stock
Solid
5 mg USD 360 In-stock
10 mg USD 570 In-stock
25 mg USD 1150 In-stock
50 mg USD 1850 In-stock
100 mg USD 2980 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

R110 is a potent, competitive inhibitor of macrophage migration inhibitory factor 2 (MIF2) tautomerase with an IC50 of 15 μM. R110 has the potential for the research of cancer diseases[1].

IC50 & Target

IC50: 15 μM (MIF2)[1]
Molecular Weight

308.83

Formula

C15H17ClN2OS
CAS No.
Appearance

Solid

Color

Off-white to light yellow

SMILES

O=C(C1=C(N)SC(C2=CC=C(Cl)C=C2)=C1)NCCCC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (161.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2380 mL 16.1901 mL 32.3803 mL
5 mM 0.6476 mL 3.2380 mL 6.4761 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.2380 mL 16.1901 mL 32.3803 mL 80.9507 mL
5 mM 0.6476 mL 3.2380 mL 6.4761 mL 16.1901 mL
10 mM 0.3238 mL 1.6190 mL 3.2380 mL 8.0951 mL
15 mM 0.2159 mL 1.0793 mL 2.1587 mL 5.3967 mL
20 mM 0.1619 mL 0.8095 mL 1.6190 mL 4.0475 mL
25 mM 0.1295 mL 0.6476 mL 1.2952 mL 3.2380 mL
30 mM 0.1079 mL 0.5397 mL 1.0793 mL 2.6984 mL
40 mM 0.0810 mL 0.4048 mL 0.8095 mL 2.0238 mL
50 mM 0.0648 mL 0.3238 mL 0.6476 mL 1.6190 mL
60 mM 0.0540 mL 0.2698 mL 0.5397 mL 1.3492 mL
80 mM 0.0405 mL 0.2024 mL 0.4048 mL 1.0119 mL
100 mM 0.0324 mL 0.1619 mL 0.3238 mL 0.8095 mL
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R110 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

R1101985622-33-0R 110R-110Macrophage migration inhibitory factor (MIF)MIF2cancerInhibitorinhibitorinhibit

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