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Results for "

SH groups

" in MedChemExpress (MCE) Product Catalog:

31

Inhibitors & Agonists

19

Fluorescent Dye

2

Biochemical Assay Reagents

5

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D2381

    Fluorescent Dye Others
    AF 488 maleimide is a thiol-reactive dye for labeling of protein SH groups, and it can be used to attach AF 488 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules. AF488 exhibits the λem and λex wavelength of 520 nm and 470 nm, respectively .
    AF 488 maleimide
  • HY-W087027

    Radionuclide-Drug Conjugates (RDCs) Cancer
    Maleimide-NOTA is a chelator for the labeling of peptides and antibodies. Maleimide-NOTA can react with cysteine .
    Maleimide-NOTA
  • HY-130911

    PROTAC Linkers Cancer
    Propargyl-PEG12-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG12-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-PEG12-SH
  • HY-135917

    PROTAC Linkers Cancer
    Propargyl-PEG6-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG6-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-PEG6-SH
  • HY-130910

    PROTAC Linkers Cancer
    Propargyl-PEG8-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG8-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-PEG8-SH
  • HY-130900

    PROTAC Linkers Cancer
    Propargyl-PEG3-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Propargyl-PEG3-SH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Propargyl-PEG3-SH
  • HY-D2497

    Fluorescent Dye Others
    Sulfo Cy7 bis-SH is a fluorescent dye that contains sulfonated Cyanine7 (Sulfo-CY7) fluorescent dye and thiol (-SH) functional group. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
    Sulfo Cy7 bis-SH
  • HY-135133

    Biochemical Assay Reagents Others
    S-Phenylsulfonylcysteine is a reagent for blocking thiol (-SH) groups on proteins and peptides .
    S-Phenylsulfonylcysteine
  • HY-D2530

    Fluorescent Dye Others
    Cy5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5-PEG-SH (MW 3400)
  • HY-D2532

    Fluorescent Dye Others
    Cy5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5-PEG-SH (MW 10000)
  • HY-D2529

    Fluorescent Dye Others
    Cy5-PEG-SH (MW 2000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5-PEG-SH (MW 2000)
  • HY-D2509

    Fluorescent Dye Others
    Cy3-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
    Cy3-PEG-SH (MW 1000)
  • HY-D2531

    Fluorescent Dye Others
    Cy5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5-PEG-SH (MW 5000)
  • HY-D2512

    Fluorescent Dye Others
    Cy3-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds .
    Cy3-PEG-SH (MW 5000)
  • HY-D2556

    Fluorescent Dye Others
    Cy5.5-PEG-SH (MW 1000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5.5-PEG-SH (MW 1000)
  • HY-D2557

    Fluorescent Dye Others
    Cy5.5-PEG-SH (MW 3400) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5.5-PEG-SH (MW 3400)
  • HY-D2559

    Fluorescent Dye Others
    Cy5.5-PEG-SH (MW 10000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5.5-PEG-SH (MW 10000)
  • HY-D2558

    Fluorescent Dye Others
    Cy5.5-PEG-SH (MW 5000) is a fluorescent labeling reagent that combines Cy5.5 (HY-D0924) fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) derivatives, and is suitable for molecular coupling. SH is highly reactive and can react with a variety of functional groups (such as maleimide) to form stable thioether bonds.
    Cy5.5-PEG-SH (MW 5000)
  • HY-D2510

    Fluorescent Dye Cancer
    Cy3-PEG-SH (MW 2000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 2000) is absorbed at 550nm and has high solubility and end-group substitution rate .
    Cy3-PEG-SH (MW 2000)
  • HY-D2513

    Fluorescent Dye Cancer
    Cy3-PEG-SH (MW 10000) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 10000) is absorbed at 550nm and has high solubility and end-group substitution rate .
    Cy3-PEG-SH (MW 10000)
  • HY-D2511

    Fluorescent Dye Cancer
    Cy3-PEG-SH (MW 3400) (Cy3-PEG-Thiol) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-SH (MW 3400) is absorbed at 550nm and has high solubility and end-group substitution rate .
    Cy3-PEG-SH (MW 3400)
  • HY-W698574

    Biochemical Assay Reagents
    Dansylamidoethyl mercaptan is a molecule that reacts with -SH groups of proteins and other sulfhydryl-containing molecules and has activity for detecting SS bonds in proteins.
    Dansylamidoethyl mercaptan
  • HY-139143

    FAAH Others
    WWL154, an analog of JZL184 that maintains the SH-reactive p-nitrophenyl carbamate group, is a FAAH-4 inhibitor .
    WWL154
  • HY-D0122

    Fluorescent Dye Others
    6-Iodoacetamidofluorescein, a sulphhydryl-specific fluorescent dye, and can be used to selectively label the -SH groups of nuclear matrix polypeptides and proteins .
    6-Iodoacetamidofluorescein
  • HY-D2448

    Fluorescent Dye Cancer
    Cy3-PEG-Thiol (Cy3-PEG-SH) is a near infrared fluorescent labeling reagent that combines Cy3 fluorescent dye, polyethylene glycol (PEG) and sulfhydryl (SH) polyethylene glycol derivatives, and is suitable for molecular coupling. Cy3-PEG-Thiol is absorbed at 550nm and has high solubility and end-group substitution rate .
    Cy3-PEG-Thiol
  • HY-D1869

    Fluorescent Dye Others
    800CW maleimide is an infrared dye that can be used for labeling molecules that contain free sulfhydryl (–SH) groups (Ex: 778 nm; Em: 796 nm). 800CW maleimide binds to plasma proteins .
    800CW maleimide
  • HY-156377

    Drug-Linker Conjugates for ADC Cancer
    Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .
    Biotin-PEG7-Maleimide
  • HY-W440896

    Liposome Others
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-146691

    Monoamine Oxidase Neurological Disease
    hMAO-B-IN-2 (compound 6j) is an orally active, potent, selective and BBB penetrated and competitive reversible hMAO-B inhibitor, with an IC50 of 4 nM. hMAO-B-IN-2 shows low toxicity and good neuroprotective effects in SH-SY5Y cell. hMAO-B-IN-2 can be used for alzheimer’s disease research . hMAO-B-IN-2 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    hMAO-B-IN-2
  • HY-D2763

    Fluorescent Dye Others
    BP Fluor 532 maleimide is a photostable, bright yellow-fluorescent dye with pH insensitive emission from pH 4 to pH 10. The excitation of BP Fluor 532 is ideally suited for the frequency-doubled Nd:YAG laser line. BP Fluor 532 dye can be conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, and is often used for the generation of stable signals in imaging and flow cytometry. Maleimide is the most popular sulfhydryl-reactive group for conjugating the dye to a thiol group on a protein, oligonucleotide thiophosphate, or low molecular weight ligand. The maleimide group specifically and efficiently reacts with reduced thiols (sulfhydryl groups, –SH) at pH 6.5 to 7.5 to form a stable thioether bond. The resulting conjugates exhibit brighter fluorescence and greater photostability than the conjugates of many other spectrally similar fluorophores.
    BP Fluor 532 maleimide
  • HY-113817

    Phosphatase Inflammation/Immunology
    SHIP1 activator 1 is an SH3 domain-containing inositol 5-phosphatase regulator with SHIP1 activating activity. SHIP1 activator 1 retains its SHIA-1 activating ability by removing unnecessary functional groups. SHIP1 activator 1 is able to activate SHIP1 in vitro, inhibit Akt phosphorylation in MOLT-4 cells, and show dose-dependent activity in a mouse model of inflammation. SHIP1 activator 1 is an important chemical tool for evaluating the potential of SHIP1 activators as inhibitors of hematopoietic diseases involving abnormal PI3K cell signaling .
    SHIP1 activator 1