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Results for "

SLE

" in MedChemExpress (MCE) Product Catalog:

17

Inhibitors & Agonists

1

Biochemical Assay Reagents

3

Peptides

8

Inhibitory Antibodies

3

Natural
Products

1

Recombinant Proteins

2

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P99219
    Sifalimumab

    MEDI-545; MDX 1103

    		 IFNAR Inflammation/Immunology
    Sifalimumab (MEDI-545) is an anti-IFNα monoclonal antibody. Sifalimumab suppresses the abnormal immune activity by binding to multiple interferon-alpha (IFNα) subtypes. Sifalimumab can be used in systemic lupus erythematosus (SLE) research .
    Sifalimumab
  • HY-P99529
    Valziflocept

    BAX1810; TAK-752

    		 Fc Receptor (FcR) Inflammation/Immunology
    Valziflocept (BAX1810; TAK-752) is a recombinant soluble human FcγRIIb receptor that targets Fc and FcγR. FcγRs bind and neutralize pathogenic IgG, thus forming a "decoy" or "scavenger" receptor that can reduce the severity of autoimmune diseases. Valziflocept can be used in studies of autoimmune diseases such as systemic lupus erythematosus (SLE) .
    Valziflocept
  • HY-P99168
    Anifrolumab
    2 Publications Verification

    		 IFNAR Inflammation/Immunology
    Anifrolumab is a type I interferon (IFN) receptor antagonist, a human monoclonal antibody. Anifrolumab blocks the activity of type I interferon. Anifrolumab can be used in systemic lupus erythematosus (SLE) research .
    Anifrolumab
  • HY-P9952
    Belimumab
    2 Publications Verification

    LymphoStat B

    		 TNF Receptor CD20 Inflammation/Immunology Cancer
    Belimumab (LymphoStat B) is a humanized IgG1λ monoclonal antibody against B-lymphocyte stimulator (BLyS) protein. Belimumab antagonizes BLyS activity in autoimmune diseases and B-lymphocyte malignancies. Belimumab can be used for systemic lupus erythematosus (SLE) research .
    Belimumab
  • HY-P99325
    Toralizumab

    IDEC-131; Anti-Human CD40 ligand Recombinant Antibody

    		 TNF Receptor Inflammation/Immunology
    Toralizumab (IDEC-131) is a humanized monoclonal antibody (mAb) against CD40L (CD154) comprised of human gamma 1 heavy chains and human kappa light chains. Toralizumab binds specifically to human CD40L on T cells, thereby preventing CD40 signaling. Toralizumab, a immunosuppressive agent, has the potential for active systemic lupus erythematosus (SLE) research .
    Toralizumab
  • HY-76082
    L-Pyroglutamic acid
    2 Publications Verification

    		 Endogenous Metabolite Inflammation/Immunology
    L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE) .
    L-Pyroglutamic acid
  • HY-P99842A
    Dapirolizumab

    		TNF Receptor Inflammation/Immunology
    Dapirolizumab is a monoclonal antibodi against CD40 ligand. Dapirolizumab targets CD40L, blocks its interaction with CD40 receptors, and inhibits adaptive immune activation. Dapirolizumab attenuates systemic lupus erythematosus .
    Dapirolizumab
  • HY-150740
    ODN 21595

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 21595 is a Guanine-Modified TLR7 and TLR9 inhibitor. ODN 21595 inhibits the release of IFN-α and IL-6 with no cytotoxic. ODN 21595 reduces the expression of CD86 and HLA-DR. ODN 21595 has the potential for the research of systemic lupus erythematosus (SLE) .
    ODN 21595
  • HY-150740A
    ODN 21595 sodium

    		Toll-like Receptor (TLR) Inflammation/Immunology
    ODN 21595 sodium is a Guanine-Modified TLR7 and TLR9 inhibitor. ODN 21595 sodium inhibits the release of IFN-α and IL-6 with no cytotoxic. ODN 21595 sodium reduces the expression of CD86 and HLA-DR. ODN 21595 sodium has the potential for the research of systemic lupus erythematosus (SLE) .
    ODN 21595 sodium
  • HY-76082A
    L-Pyroglutamic acid sodium

    		Biochemical Assay Reagents Endogenous Metabolite Inflammation/Immunology
    Sodium L-pyroglutamate is a biochemical reagent that can be used as a biological material or organic compound for life science related research. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE) .
    L-Pyroglutamic acid sodium
  • HY-76082R
    L-Pyroglutamic acid (Standard)

    		Endogenous Metabolite Inflammation/Immunology
    L-Pyroglutamic acid (Standard) is the analytical standard of L-Pyroglutamic acid. This product is intended for research and analytical applications. L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid standard can be used as a biomarker for systemic lupus erythematosus (SLE) .
    L-Pyroglutamic acid (Standard)
  • HY-P99893
    Rozibafusp alfa

    AMG-570

    		 CD28 TNF Receptor Others
    Rozibafusp alfa (AMG-570) is a humanized IgG2-κ monoclonal antibody targets ICOSL and BAFF. Prezalumab demonstrates beneficial activities on the arthritis of systemic lupus erythematosus. Prezalumab can be used for the research of sjogren's syndrome cutaneous lupus erythematosus, psoriasis and systemic lupus erythematosus (SLE) .
    Rozibafusp alfa
  • HY-105037
    Forigerimod

    IPP-201101

    		 Autophagy Inflammation/Immunology
    Forigerimod (IPP-201101) is a CD4 T-cell modulator. Forigerimod is a 21-amino-acid fragment of U1 small nuclear ribonucleoprotein 70 kDa that is phosphorylated at Ser140. Forigerimod can potently inhibit autophagy. Forigerimod can be used for the research of autoimmune disorders, such as systemic lupus erythematosus (SLE) .
    Forigerimod
  • HY-105037A
    Forigerimod TFA

    IPP-201101 TFA

    		 Autophagy Inflammation/Immunology
    Forigerimod TFA (IPP-201101 TFA) is a CD4 T-cell modulator. Forigerimod TFA is a 21-amino-acid fragment of U1 small nuclear ribonucleoprotein 70 kDa that is phosphorylated at Ser140. Forigerimod TFA can potently inhibit autophagy. Forigerimod can be used for the research of autoimmune disorders, such as systemic lupus erythematosus (SLE) .
    Forigerimod TFA
  • HY-P3560
    Edratide

    TV 4710

    		 Apoptosis Inflammation/Immunology
    Edratide (TV 4710) is a synthetic peptide of 19 amino acid based on the complementarity-determining region 1 (CDR1) of a human anti-DNA antibody that expresses a major idiotype denoted 16/6 Id. Edratide reduces the rates of apoptosis (Apoptosis) and down-regulates of caspase-8 and caspase-3, up-regulates Bcl-xL. Edratide has the potential for the research of systemic lupus erythematosus (SLE) .
    Edratide
  • HY-147390
    MIF098

    		Macrophage migration inhibitory factor (MIF) Inflammation/Immunology
    MIF098 is a macrophage migration inhibitory factor (MIF) antagonist. MIF098 inhibits proliferation, migration and fibrosis of pulmonary smooth muscle cells. MIF098 can be used for immunoinflammation-related disease research .
    MIF098
  • HY-P99414
    Prezalumab

    AMG 557

    		 CD28 Inflammation/Immunology
    Prezalumab (AMG 557) is a monoclonal antibody targeting ICOSL that has synergistic anti-inflammatory activity with CD28 antibody inhibitors .
    Prezalumab

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