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Results for "

SRF

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) CCR (1) CD47 (1) Interleukin Related (2) Microtubule/Tubulin (1) Mitochondrial Metabolism (1) NTPDase (1) Ras (8) ROCK (1) Small Interfering RNA (siRNA) (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (4) Inflammation/Immunology (1) Metabolic Disease (2) Neurological Disease (1)
Oligonucleotides:	Human Pre-designed siRNA Sets (1) siRNAs (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-118748

Suprafenacine SRF	Microtubule/Tubulin	Cancer
Suprafenacine is a cell permeable, tubulin-destabilizing molecule which bind microtubules at the colchicine-binding site and inhibit polymerization. Suprafenacine can induce G2/M cell cycle arrest and apoptosis, and can be used for cancer research .

HY-P990024

Casdozokitug SRF-388	Interleukin Related	Cancer
Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27 .

HY-P99533

Urabrelimab SRF-231; SRF231	CD47 Interleukin Related	Cancer
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .

HY-P990068

Perenostobart SRF617	NTPDase	Cancer
Perenostobart is a human immunoglobulin G4-kappa, anti-ENTPD1/CD39 monoclonal antibody. Perenostobart is an immunostimulant and antineoplastic .

HY-153078

*MRTF/SRF-IN-1*	Ras	Cancer
MRTF/SRF-IN-1 (example 41) is an inhibitor of both myocardin-related transcription factor and serum response factor (MRTF/SRF). MRTF/SRF-IN-1 can be used for research for preventing cancer and fibrosis .

HY-120855

CCG-100602 1 Publications Verification	Ras	Cardiovascular Disease
CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF .

HY-108361

CCG-203971 1 Publications Verification	Ras	Inflammation/Immunology Cancer
CCG-203971 is a second-generation *Rho/MRTF/SRF* pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC₅₀ =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC₅₀ of 4.2 μM. Potential anti-metastasis Agent .

HY-RS13760

SRF Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SRF Human Pre-designed siRNA Set A contains three designed siRNAs for SRF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SRF Human Pre-designed siRNA Set A SRF Human Pre-designed siRNA Set A

HY-P991061

CHS-114 SRF-114	CCR	Cancer
CHS-114 (SRF-114) is a fully human IgG1 antibody that targets CCR8. CHS-114 has the potential for the study of head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-130011

CCG-232964	ROCK Ras	Neurological Disease Cancer
CCG-232964 is an orally active inhibitor of *Rho/MRTF/SRF*. CCG-232964 inhibits LPA-induced CTGF gene expression .

HY-13991

CCG-1423 Maximum Cited Publications 12 Publications Verification	Ras Apoptosis	Cancer
CCG-1423 is an inhibitor of *Rho/MRTF/SRF* pathway. CCG-1423 shows activities in several cancer cells. CCG-1423 is a promising lead compound for the development of novel pharmacologic tools, and it can be used for the research of cancer and diabetes .

HY-111432

CCG-232601	Ras	Others
CCG-232601 (compound 8f) is a potent and orally active *Rho/MRTF/SRF* transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma .

HY-162904

BPU17	Mitochondrial Metabolism	Cardiovascular Disease
BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent .

HY-162969

MRTF-A-IN-2	Ras	Cardiovascular Disease Metabolic Disease
MRTF-A-in-2 (Compound 16) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging .

HY-162968

MRTF-A-IN-1	Ras	Cardiovascular Disease Metabolic Disease
MRTF-A-in-1 (Compound 14) is MRTF-A inhibitor. MRTF-A-in-1 can inhibit cell proliferation and induce HCC cell aging .

Cat. No.	Product Name	Target	Research Area

HY-P990024

Casdozokitug SRF-388	Interleukin Related	Cancer
Casdozokitug (SRF-388) is an IgG1κ antibody targeting IL27 .

HY-P99533

Urabrelimab SRF-231; SRF231	CD47 Interleukin Related	Cancer
Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .

HY-P990068

Perenostobart SRF617	NTPDase	Cancer
Perenostobart is a human immunoglobulin G4-kappa, anti-ENTPD1/CD39 monoclonal antibody. Perenostobart is an immunostimulant and antineoplastic .

HY-P991061

CHS-114 SRF-114	CCR	Cancer
CHS-114 (SRF-114) is a fully human IgG1 antibody that targets CCR8. CHS-114 has the potential for the study of head and neck squamous cell carcinoma (HNSCC). The isotype control for CHS-114 can refer to Human IgG1 kappa, Isotype Control (HY-P99001) .

Cat. No.	Compare	Product Name	Species	Source

HY-P71821

	PTK7 Protein, Human (P.pastoris, His) CCK 4; CCK-4; Colon carcinoma kinase 4; Inactive tyrosine-protein kinase 7; Serum response factor; SRF; Tyrosine-protein kinase-like 7	Human	P. pastoris
	The PTK7 protein is an inactive tyrosine kinase that plays a key role in both non-canonical and canonical Wnt signaling pathways. Effects include cell adhesion, migration, polarity, proliferation, actin cytoskeleton reorganization, and apoptosis. PTK7 Protein, Human (P.pastoris, His) is the recombinant human-derived PTK7 protein, expressed by P. pastoris , with N-6*His labeled tag.

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Cat. No.	Compare	Product Name	Application	Reactivity

HY-P83523

	General Transcription Factor II I Antibody (YA3268) GTF2I; BAP135; WBSCR6; General transcription factor II-I; GTFII-I; TFII-I; Bruton tyrosine kinase-associated protein 135; BAP-135; BTK-associated protein 135; SRF-Phox1-interacting protein; SPIN; Williams-Beuren syndrome chromosomal region	WB, IHC-F, IHC-P, ICC/IF	Human
	General Transcription Factor II I Antibody (YA3268) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3268), targeting General Transcription Factor II I, with a predicted molecular weight of 112 kDa (observed band size: 135/138 kDa). General Transcription Factor II I Antibody (YA3268) can be used for WB, IHC-F, IHC-P, ICC/IF experiment in human background.

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SRF Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
SRF Human Pre-designed siRNA Set A contains three designed siRNAs for SRF gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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