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Isoforms Recommended: VDAC1
Results for "

VDAC1

" in MedChemExpress (MCE) Product Catalog:

9

Inhibitors & Agonists

1

Fluorescent Dye

1

Antibodies

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135885
    VBIT-12
    2 Publications Verification

    		 VDAC Neurological Disease
    VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1 [1].
    VBIT-12
  • HY-111217
    AKOS-22

    		VDAC Mitochondrial Metabolism Neurological Disease Cancer
    AKOS-22 is a potent mitochondrial protein VDAC1 (voltage-dependent anion channel 1) inhibitor (Kd=15.4 μM). AKOS-22 interacts with VDAC1 and inhibiting both VDAC1 oligomerization and apoptosis. AKOS-22 protects against mitochondrial dysfunction [1].
    AKOS-22
  • HY-129122
    VBIT-4
    5+ Cited Publications

    		 VDAC Cardiovascular Disease Neurological Disease
    VBIT-4 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 17 μM. VBIT-4, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases [1].
    VBIT-4
  • HY-108937
    NSC 15364
    5+ Cited Publications

    		 VDAC Apoptosis Cardiovascular Disease Neurological Disease
    NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis [1].
    NSC 15364
  • HY-D0086
    DIDS sodium salt
    Maximum Cited Publications
    13 Publications Verification

    MDL101114ZA

    		 VDAC RAD51 Cancer
    DIDS sodium salt (MDL101114ZA) is a dual inhibitor of ABCA1 and VDAC1. DIDS also inhibits RAD51, inhibiting RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research [1] .
    DIDS sodium salt
  • HY-RS15629
    VDAC1 Human Pre-designed siRNA Set A

    		Small Interfering RNA (siRNA) Others

    VDAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for VDAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

    VDAC1 Human Pre-designed siRNA Set A
    VDAC1 Human Pre-designed siRNA Set A
  • HY-135571
    VBIT-3

    		VDAC Cardiovascular Disease Neurological Disease
    VBIT-3 is an inhibitor of voltage-dependent anion channel 1 (VDAC1) oligomerization with a binding affinity (Kd) of 31.3 μM. VBIT-3, as an apoptosis inhibitor, can be used for therapeutic purposes in apoptosis-associated disorders, such as neurodegenerative and cardiovascular diseases [1].
    VBIT-3
  • HY-121693
    DIDS

    MDL101114ZA free base

    		 VDAC RAD51 Cancer
    DIDS is a dual inhibitor of ABCA1 and VDAC1. DIDS also inhibits RAD51, inhibiting RAD51-mediated homologous pairing and strand exchange reactions. DIDS inhibits anion exchange and binding to red blood cell membranes, inhibits the activation of caspase-3 and -9, and can be used in cancer research [1] .
    DIDS
  • HY-161027
    DHP-B

    		Apoptosis Cancer
    DHP-B possesses anti-cancer activity and induces apoptosis. DHP-B covalently binds to Cys96 of CPT1A, blocks FAO, and disrupts the mitochondrial CPT1A-VDAC1 interaction, leading to increased mitochondrial permeability and reduced oxygen consumption and energy metabolism in CRC cells. DHP-B can be isolated from the plant Peperomia dindygulensis [1].
    DHP-B

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