VTCN1

By Targets:	CD276/B7-H3 (3) CD3 (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Cancer (1) Inflammation/Immunology (4)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990059

Puxitatug	CD276/B7-H3	Cancer
Puxitatug is an immunoglobulin G1-κ, anti-[Homo sapiens VTCN1 (Vset domain containing T cell activation inhibitor 1, B7 family member H4, B7H4, B7-H4)] Homo sapiens monoclonal antibody ^[1].

HY-RS17471

Vtcn1 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)
Vtcn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vtcn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Vtcn1 Mouse Pre-designed siRNA Set A Vtcn1 Mouse Pre-designed siRNA Set A

HY-RS15721

VTCN1 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
VTCN1 Human Pre-designed siRNA Set A contains three designed siRNAs for VTCN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

VTCN1 Human Pre-designed siRNA Set A VTCN1 Human Pre-designed siRNA Set A

HY-P990918

Emiltatug	CD276/B7-H3	Inflammation/Immunology
HY-P990918 is an *VTCN1*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) ^[1].

HY-P990996

Felmetatug	CD276/B7-H3	Inflammation/Immunology
HY-P990996 is an *VTCN1*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) ^[1].

HY-P990953

Zubotamig Gen1047	CD3	Inflammation/Immunology
HY-P990953 is an *CD3E/VTCN1*-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody ^[1].

Cat. No.	Product Name	Target	Research Area

HY-P990341

*Anti-B7-H4/VTCN1* Antibody**	Inhibitory Antibodies	Inflammation/Immunology
Anti-B7-H4/VTCN1 Antibody is a CHO-expressed human antibody that targets *B7-H4/VTCN1. The Anti-B7-H4/VTCN1* Antibody contains a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for Anti-B7-H4/VTCN1 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-P990059

Puxitatug	CD276/B7-H3	Cancer
Puxitatug is an immunoglobulin G1-κ, anti-[Homo sapiens VTCN1 (Vset domain containing T cell activation inhibitor 1, B7 family member H4, B7H4, B7-H4)] Homo sapiens monoclonal antibody ^[1].

HY-P990918

Emiltatug	CD276/B7-H3	Inflammation/Immunology
HY-P990918 is an *VTCN1*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) ^[1].

HY-P990996

Felmetatug	CD276/B7-H3	Inflammation/Immunology
HY-P990996 is an *VTCN1*-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001) ^[1].

HY-P990953

Zubotamig Gen1047	CD3	Inflammation/Immunology
HY-P990953 is an *CD3E/VTCN1*-targeting Ig(G1 -κ_G1 -λ2) type chimeric human antibody ^[1].

Species:	Human (6) Rhesus Macaque (2) Mouse (3) Rat (1)
Tag:	His (8) Avi (3) Fc (4)
Source:	HEK293 (11) Sf9 insect cells (1)

Cat. No.	Compare	Product Name	Species	Source

HY-P74394

	B7-H4 Protein, Mouse (HEK293, His) 1 Publications Verification V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4	Mouse	HEK293
	The B7-H4 protein acts as a negative regulator and inhibits T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. Significant significance can be observed when expressed on tumor macrophages, cooperating with regulatory T cells (Tregs) to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-H4 Protein, Mouse (HEK293, His) is 228 a.a., with molecular weight of ~26.6 kDa.

HY-P74395

	B7-H4 Protein, Human (HEK293, His) V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4	Human	HEK293
	The B7-H4 protein acts as a negative regulator, inhibiting T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Human (HEK293, His) is the recombinant human-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P75485

	B7-H4 Protein, Rat (HEK293, His) V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4	Rat	HEK293
	The B7-H4 protein acts as a negative regulator, inhibiting T cell activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells (Tregs) to suppress tumor-associated antigen-specific T cell immunity and create an immunosuppressive microenvironment. B7-H4 Protein, Rat (HEK293, His) is the recombinant rat-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag. The total length of B7-H4 Protein, Rat (HEK293, His) is 228 a.a., with molecular weight of 42-65 kDa.

HY-P78073

	B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi) B7H4; B7-H4; B7S1; B7h.5; B7x; FLJ22418; VTCN1; PRO1291	Human	HEK293
	The B7-H4 protein acts as a negative regulator, inhibiting T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived B7-H4 protein, expressed by HEK293 , with C-Avi, C-His labeled tag.

HY-P7641

	B7-H4 Protein, Mouse (HEK293, Fc) rMuB7-H4, C-Fc; V-set domain containing T-cell activation inhibitor 1; B7 homolog 4; Protein B7S1; B7-H4;	Mouse	HEK293
	B7-H4 Protein, Mouse (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.

HY-P7640

	B7-H4 Protein, Human (HEK293, Fc) rHuB7-H4, C-Fc; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1	Human	HEK293
	B7-H4 Protein, Human (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.

HY-P77541

	B7-H4 Protein, Human (Biotinylated, HEK293, His) V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4	Human	HEK293
	The B7-H4 protein acts as a negative regulator, inhibiting T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Human (Biotinylated, HEK293, His) is the recombinant human-derived B7-H4 protein, expressed by HEK293 , with C-His labeled tag.

HY-P74393

	B7-H4 Protein, Mouse (sf9, His) V-set domain containing T-cell activation inhibitor 1; VTCN1; Protein B7S1; B7-H4	Mouse	Sf9 insect cells
	The B7-H4 protein acts as a negative regulator and inhibits T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. Significant significance can be observed when expressed on tumor macrophages, cooperating with regulatory T cells (Tregs) to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Mouse (sf9, His) is the recombinant mouse-derived B7-H4 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of B7-H4 Protein, Mouse (sf9, His) is 228 a.a., with molecular weight of ~26.6 kDa.

HY-P78390

	B7-H4 Protein, Human (HEK293, His-Avi) B7H4; B7-H4; B7S1; B7h.5; B7x; FLJ22418; VTCN1; PRO1291	Human	HEK293
	The B7-H4 protein acts as a negative regulator, inhibiting T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Human (HEK293, His-Avi) is the recombinant human-derived B7-H4 protein, expressed by HEK293 , with C-His, C-Avi labeled tag.

HY-P72341

	B7-H4 Protein, Human (Biotinylated, HEK293, Fc-Avi) B7S1; B7x; VTCN1; B7h.5; B7S1VCTN1; B7XPRO1291; FLJ22418; Protein B7S1; T cell costimulatory molecule B7x; V-set domain containing T cell activation inhibitor 1	Human	HEK293
	The B7-H4 protein acts as a negative regulator, inhibiting T cell-mediated immune responses, including activation, proliferation, cytokine production, and cytotoxicity. When expressed on tumor macrophages, it cooperates with regulatory T cells to suppress tumor-associated antigen-specific T cell immunity. B7-H4 Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived B7-H4 protein, expressed by HEK293 , with C-Avi, C-hFc labeled tag.

HY-P7642

	B7-H4 Protein, Rhesus macaque (HEK293, His) rRhB7-H4, His; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1	Rhesus Macaque	HEK293
	B7-H4 Protein, Rhesus macaque (HEK293, His) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.

HY-P7643

	B7-H4 Protein, Rhesus macaque (HEK293, Fc) rRhB7-H4, C-Fc; B7-H4; Protein B7S1; T cell costimulatory molecule B7x; V-set domain-containing T-cell activation inhibitor 1	Rhesus Macaque	HEK293
	B7-H4 Protein, Rhesus macaque (HEK293, Fc) may participate in negative regulation of cell-mediated immunity in peripheral tissues. Cell-associated B7-H4 could also inhibit T cell response. B7-H4 acts as a morphogenic factor for cancer cells.

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Cat. No.	Product Name		Classification

HY-RS17471

Vtcn1 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Vtcn1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Vtcn1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS15721

VTCN1 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
VTCN1 Human Pre-designed siRNA Set A contains three designed siRNAs for VTCN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

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