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Results for "

anti-aggregation

" in MedChemExpress (MCE) Product Catalog:

16

Inhibitors & Agonists

6

Natural
Products

1

Click Chemistry

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-N6661
    Verbenone

    (-)-Verbenone

    		 Others Infection
    Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis . Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones .
    Verbenone
  • HY-17482
    Difenpiramide

    Z-876

    		 Others Inflammation/Immunology
    Difenpiramide (Z-876) is a bisphenylalcanoic derivative with marked anti-inflammatory, analgesic, antipyretic and uricosuric properties. Difenpiramide has platelet anti-aggregation activity .
    Difenpiramide
  • HY-118752
    Fentiazac

    		COX Inflammation/Immunology
    Fentiazac, alkanoic acid derivative, is an orally active non-steroidal anti-inflammatory agent, with analgesic, antipyretic and platelet anti-aggregation activity. Fentiazac can be used to research inflammatory diseases such as rheumatoid arthritis, osteoarthritis and tendinitis .
    Fentiazac
  • HY-N0375
    18α-Glycyrrhetinic acid
    1 Publications Verification

    		 Proteasome NF-κB Apoptosis Neurological Disease Inflammation/Immunology Cancer
    18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis .
    18α-Glycyrrhetinic acid
  • HY-146314
    MAO-B-IN-9

    		Monoamine Oxidase Amyloid-β Neurological Disease
    MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects . MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    MAO-B-IN-9
  • HY-N12360
    2,3-Dehydrosilybin A

    		Amyloid-β Neurological Disease
    2,3-Dehydrosilybin A is a pro-longevity and anti-aggregation compound .
    2,3-Dehydrosilybin A
  • HY-N12360R
    2,3-Dehydrosilybin A (Standard)

    		Amyloid-β Neurological Disease
    2,3-Dehydrosilybin A (Standard) is the analytical standard of 2,3-Dehydrosilybin A. This product is intended for research and analytical applications. 2,3-Dehydrosilybin A is a pro-longevity and anti-aggregation compound .
    2,3-Dehydrosilybin A (Standard)
  • HY-N6661R
    Verbenone (Standard)

    		Others Infection
    Verbenone (Standard) is the analytical standard of Verbenone. This product is intended for research and analytical applications. Verbenone ((-)-Verbenone) is a natural terpene in leaves of the tree, Verbena officinalis . Verbenone has anti-aggregation pheromone and interrupts the attraction of bark beetles to their aggregation pheromones .
    Verbenone (Standard)
  • HY-19255
    FK-788

    		Prostaglandin Receptor Others
    FK-788 is a PGI(2) and IP agonist with a strong anti-aggregation effect, with an IC50 of 18 nM and a high binding affinity for the human recombinant IP receptor, with a Ki value of 20 nM .
    FK-788
  • HY-N0375R
    18α-Glycyrrhetinic acid (Standard)

    		Proteasome NF-κB Apoptosis Neurological Disease Inflammation/Immunology Cancer
    18α-Glycyrrhetinic acid (Standard) is the analytical standard of 18α-Glycyrrhetinic acid. This product is intended for research and analytical applications. 18α-Glycyrrhetinic acid, a diet-derived compound, is an inhibitor of NF-kB and an activator of proteasome, which serves as pro-longevity and anti-aggregation factor in a multicellular organism. 18α-Glycyrrhetinic acid induces apoptosis .
    18α-Glycyrrhetinic acid (Standard)
  • HY-146005
    Tau-aggregation and neuroinflammation-IN-1

    		Microtubule/Tubulin Neurological Disease Inflammation/Immunology
    Tau-aggregation and neuroinflammation-IN-1 is a potent tau-aggregation and neuroinflammation inhibitor. Tau-aggregation and neuroinflammation-IN-1 exhibits remarkable inhibitory activities against AcPHF6 and full-length tau aggregation. Tau-aggregation and neuroinflammation-IN-1 has a low cytotoxicity and reduced NO release in LPS-stimulated BV2 cells. Tau-aggregation and neuroinflammation-IN-1 can reverse okadaic acid-induced memory impairment in rats .
    Tau-aggregation and neuroinflammation-IN-1
  • HY-159941
    tau-0N4R-IN-1

    		α-synuclein Neurological Disease
    tau-0N4R-IN-1 (Compound 6T) is an BBB-penetrable inhibitor of tau 0N4R oligomerization. tau-0N4R-IN-1 effectively inhibits the fibrosis of tau 0N4R, 2N3R, and 2N4R, exhibits an anti-seeding effect on tau in vitro, reduces the oligomerization of α-syn dose-dependently, and prevents formation of α-syn inclusions. tau-0N4R-IN-1 is stable in mouse microsomes and reduces Aβ plaques in brain tissues from AD patients. tau-0N4R-IN-1 has good pharmacokinetic properties in mice .
    tau-0N4R-IN-1
  • HY-147668
    α-Synuclein inhibitor 6

    		α-synuclein Neurological Disease
    α-Synuclein inhibitor 6 (compound 3ge) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.70 μM and inhibition ratio at 30 μM of 94.4% .
    α-Synuclein inhibitor 6
  • HY-147666
    α-Synuclein inhibitor 4

    		α-synuclein Neurological Disease
    α-Synuclein inhibitor 4 (compound 3gh) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 0.98 μM and inhibition ratio at 30 μM of 91.2% .
    α-Synuclein inhibitor 4
  • HY-147669
    α-Synuclein inhibitor 7

    		α-synuclein Neurological Disease
    α-Synuclein inhibitor 7 (compound 3gf) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.95 μM and inhibition ratio at 30 μM of 85.8% .
    α-Synuclein inhibitor 7
  • HY-147667
    α-Synuclein inhibitor 5

    		α-synuclein Neurological Disease
    α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3% .
    α-Synuclein inhibitor 5