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antiarrhythmic properties

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (1) Akt (5) Calcium Channel (3) GSK-3 (1) Isotope-Labeled Compounds (1) LRRK2 (1) Monoamine Oxidase (1) Phosphodiesterase (PDE) (1) PI3K (5) Sodium Channel (1) Thyroid Hormone Receptor (1)
By Research Areas:	Cancer (6) Cardiovascular Disease (15) Neurological Disease (2)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-105454

Recainam Wy-42362	Others	Cardiovascular Disease
Recainam (Wy-42362) is an orally active anti-arrhythmic agent with Class I electrophysiological properties. Recainam suppresses complex ventricular arrhythmias. Racainam exhibits a good pharmacokinetic character in Sprague Dawley rats .

HY-15293B

JTV-519 hemifumarate K201 hemifumarate	Calcium Channel	Cardiovascular Disease
JTV-519 hemifumarate (K201 hemifumarate) is a Ca ²⁺-dependent blocker of sarcoplasmic reticulum Ca ²⁺-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties .

HY-N0728

α-Linolenic acid 4 Publications Verification	PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-116119

BDF 9148	Sodium Channel	Cardiovascular Disease
BDF 9148 is a sodium-channel activator with antiarrhythmic properties that produces a significant CAMP-independent positive inotropic effect in left ventricular myocardium from failing human hearts. BDF 9148 is promising for research of myocardial failure .

HY-19679

Quinacainol PK 10139	Others	Cardiovascular Disease
Quinacainol is a Class I antiarrhythmic drug with antiarrhythmic activity. Quinacainol improves arrhythmias by affecting the electrophysiological properties of the heart. Quinacainol is 5 to 10 times more effective for arrhythmia than Quinidine (HY-150123). Quinacainol can be used to study cardiac electrophysiology .

HY-106207

Celivarone SSR149744C	Others	Cardiovascular Disease
Celivarone (SSR149744C) is a orally active noniodinated benzofuran derivative with antiarrhythmic properties. Celivarone has the potential for atrial fibrillation and in ventricular arrhythmias research .

HY-105454A

Recainam hydrochloride Wy-42362 hydrochloride	Others	Cardiovascular Disease
Recainam (Wy-42362) hydrochloride is an orally active anti-arrhythmic agent with Class I electrophysiological properties. Recainam suppresses complex ventricular arrhythmias. Racainam hydrochloride exhibits a good pharmacokinetic character in Sprague Dawley rats .

HY-15293

JTV-519 K201	Calcium Channel	Cardiovascular Disease
JTV-519 (K201) is a Ca ²⁺-dependent blocker of sarcoplasmic reticulum Ca ²⁺-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties .

HY-15293A

JTV-519 free base K201 free base	Calcium Channel	Cardiovascular Disease
JTV-519 free base (K201 free base) is a Ca ²⁺-dependent blocker of sarcoplasmic reticulum Ca ²⁺-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties .

HY-N0728A

α-Linolenic acid sodium ALA; C18:3 (9Z,12Z,15Z); C18:3 n-3	Akt PI3K	Cardiovascular Disease Cancer
α-Linolenic acid sodium, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid sodium can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid sodium possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

HY-40294

Indazole	Monoamine Oxidase GSK-3 LRRK2	Cardiovascular Disease Neurological Disease Cancer
Indazole, also called isoindazole, a heterocyclic aromatic organic compound. Its derivatives display a broad variety of biological activities including anti-inflammatory, antibacterial, anti-HIV, antiarrhythmic, antifungal and antitumour properties. Indazole and its derivatives can be used for research of cancer, neurological disorders, cardiovascular diseases, gastrointestinal diseases .

HY-N0728S2

α-Linolenic acid-d14	PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S

α-Linolenic acid-d5	PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S3

α-Linolenic acid-13C18	Isotope-Labeled Compounds PI3K Akt	Cardiovascular Disease Cancer
α-Linolenic acid- ¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-120026

KB130015 KB015	Thyroid Hormone Receptor	Neurological Disease
KB130015 (KB015) is an orally active and potent ThRα and ThRβ (Thyroid Hormone Receptor) inhibitor, with IC₅₀ values of 4.5 and 5.1 μM, respectively. KB130015 has antiarrhythmic properties. KB130015 markedly slows the kinetics of inactivation of Na ⁺ channels. KB130015 opens large-conductance Ca ²⁺-activated K ⁺ channels and relaxes vascular smooth muscle .

HY-117181

UK-1745	Phosphodiesterase (PDE) Adrenergic Receptor	Cardiovascular Disease
UK-1745 is a cardiotonic agent with vasodilating and antiarrhythmic properties. It increases intracellular levels of cyclic adenosine monophosphate (cAMP) in cardiomyocytes by inhibiting phosphodiesterase III, thereby enhancing myocardial contractility. Additionally, UK-1745 exhibits β-adrenergic receptor blocking activity, which helps reduce the oxygen consumption of the heart and prevent calcium overload. These characteristics make UK-1745 a promising candidate for research in congestive heart failure .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N0728

α-Linolenic acid 4 Publications Verification	Cardiovascular Disease Structural Classification Natural Products Classification of Application Fields Source classification Plants Endogenous metabolite Microorganisms Labiatae Disease markers Erigeron breviscapus (Vant.) Hand.-Mazz. Disease Research Fields Cardiovascular System Disorder	PI3K Akt
α-Linolenic acid, isolated from Perilla frutescens, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer .

Cat. No.	Product Name	Chemical Structure

HY-N0728S2

α-Linolenic acid-d14
α-Linolenic acid-d₁₄ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S

α-Linolenic acid-d5
α-Linolenic acid-d₅ is the deuterium labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

HY-N0728S3

α-Linolenic acid-13C18
α-Linolenic acid- ¹³C₁₈ is the ¹³C labeled α-Linolenic acid. α-Linolenic acid, isolated from seed oils, is an essential fatty acid that cannot be synthesized by humans. α-Linolenic acid can affect the process of thrombotic through the modulation of PI3K/Akt signaling. α-Linolenic acid possess the anti-arrhythmic properties and is related to cardiovascular disease and cancer[1].

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antiarrhythmic properties

Inhibitors & Agonists

NaturalProducts

Isotope-Labeled Compounds

Natural
Products