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Results for "

bio-conjugation

" in MedChemExpress (MCE) Product Catalog:

34

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6

Fluorescent Dye

8

Biochemical Assay Reagents

11

Click Chemistry

1

Oligonucleotides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-139014
    N-ε-propargyloxycarbonyl-L-lysine
    1 Publications Verification

    H-​L-​Lys(Poc)​-​OH

    		 Fluorescent Dye Cancer
    N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-ε-propargyloxycarbonyl-L-lysine
  • HY-128676
    N-ε-propargyloxycarbonyl-L-lysine hydrochloride
    1 Publications Verification

    H-​L-​Lys(Poc)​-​OH hydrochloride

    		 Amino Acid Derivatives Cancer
    N-ε-propargyloxycarbonyl-L-lysine (H-L-Lys(Poc)-OH) hydrochloride is a lysine-based unnatural amino acid (UAA). N-ε-propargyloxycarbonyl-L-lysine is widely used for bio-conjugation of fluorescent probes in diverse organisms from E. coli to mammalian cells even in animals . N-ε-propargyloxycarbonyl-L-lysine (hydrochloride) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    N-ε-propargyloxycarbonyl-L-lysine hydrochloride
  • HY-160155
    Cholesteryl-Teg azide

    		Biochemical Assay Reagents Others
    Cholesteryl-Teg azide is a cholesterol azide and can be used as a ligand for bioconjugation. Cholesteryl-Teg azide can modify RNA strands .
    Cholesteryl-Teg azide
  • HY-151752
    Mal-AMCHC-N-Propargylamide

    		ADC Linker Others
    Mal-AMCHC-N-Propargylamide is a click chemistry reagent containing an azide group. Mal-AMCHC-N-Propargylamide can be a bio-conjugation reagent for antibody-agent-conjugate synthesis using Click-Chemistry .
    Mal-AMCHC-N-Propargylamide
  • HY-D1403
    L-Biotin-NH-5MP

    		Fluorescent Dye Cancer
    L-Biotin-NH-5MP is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
    L-Biotin-NH-5MP
  • HY-D1406
    L-Biotin-NH-5MP-Br

    		Fluorescent Dye Others
    L-Biotin-NH-5MP-Br is a biotin-conjugated 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation .
    L-Biotin-NH-5MP-Br
  • HY-W800727
    BB1-acid

    		Biochemical Assay Reagents Others
    BB1-acid was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins.
    BB1-acid
  • HY-D1404
    5MP-Propargyl

    		Fluorescent Dye Others
    5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation . 5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    5MP-Propargyl
  • HY-D1407
    Br-5MP-Propargyl

    		Fluorescent Dye Others
    Br-5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP). 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation . Br-5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Br-5MP-Propargyl
  • HY-151636
    10-Undecynoyl-OSu

    		ADC Linker Others
    10-Undecynoyl-OSu is a click chemistry reagent. 10-Undecynoyl-OSu is used as a hydrophobic bioconjugation linker that can be further modified at the alkyne using Click-chemistry .
    10-Undecynoyl-OSu
  • HY-168939A
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 2000)
  • HY-168939
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 1000)
  • HY-111945
    Cys modifier 1

    		Fluorescent Dye Others
    Cys modifier 1 (compound 7) is a cysteine-selective protein modifier for protein bioconjugation. A fluorescent carbonylacrylic derivative bearing nitrobenzofurazan (λex=465nm and λem539 nm)[1].
    Cys modifier 1
  • HY-168939C
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 5000)
  • HY-W800726
    BB1-NHS ester

    		Biochemical Assay Reagents Others
    BB1-NHS ester is amine reactive at pH 7-9 to form a stable, irreversible amide bond. It was used in a unique chemselective "unclickable' bioconjugation strategy to site specifically modify proteins.
    BB1-NHS ester
  • HY-168939B
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400) is a derivative of polyethylene glycol, which can be used for bioconjugation, drug delivery, PEG hydrogel, crosslinker and surface functionalization .
    Poly(ethylene glycol) 2-mercaptoethyl ether acetic acid (Mn 3400)
  • HY-D1402
    5MP-Fluorescein

    		Fluorescent Dye Others
    5MP-Fluorescein (compound 3e) is a fluorescein dye base on 5-Methylene pyrrolone (5MP).5-Methylene pyrrolones are highly thiol-specific and tracelessly removable bioconjugation tools .
    5MP-Fluorescein
  • HY-151759
    Sulfo-Cy5-TCO

    		Fluorescent Dye Others
    Sulfo-Cy5-TCO is a click chemistry reagent containing a TCO group. Sulfo-Cy5-TCO is water soluble dye, which is highly reactive with tetrazines and methyltetrazines with the fastest bioconjugation speed .
    Sulfo-Cy5-TCO
  • HY-Y0623
    N-Hydroxysuccinimide

    HOSu; 1-Hydroxy-2,5-pyrrolidinedione

    		 Biochemical Assay Reagents Others
    N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is an activated ester commonly used in bioconjugation technologies such as protein labeling with fluorescent dyes and enzymes, chromatography supports, beads, nanoparticles, and microarrays Surface activation of glass slides, and chemically synthesized peptides .
    N-Hydroxysuccinimide
  • HY-W190925
    APN-C3-biotin

    		Biochemical Assay Reagents Others
    APN-C3-biotin is a heterobifunctional linker containing an APN moiety with exquisite chemoselectivity for cysteine and Biotin. The superior stability of APN-cysteine conjugates in aqueous media, human plasma, and living cells makes this new thiol-click reaction a promising methodology for applications in bioconjugation.
    APN-C3-biotin
  • HY-W591965
    t-Boc-aminooxy-pentane-amine

    		Biochemical Assay Reagents Others
    t-Boc-Aminooxy-pentane-amine is a linker containing an aminooxy group and a primary amine. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.
    t-Boc-aminooxy-pentane-amine
  • HY-172290
    Benzyl N1-[PEG1-NHS]-N6-(t-Boc)-L-lysinate

    		ADC Linker Cancer
    Benzyl N1-[PEG1-NHS] -N6-(t-Boc)-L-lysinate is a multifunctional ADC linker consisting of a terminal benzyl group, one PEG unit, an NHS ester, and a t-Boc-protected L-lysine, often used for bioconjugation and chemical modifications in R&D.
    Benzyl N1-[PEG1-NHS]-N6-(t-Boc)-L-lysinate
  • HY-W440905
    DSPE-PEG-Vinylsulfone (MW 2000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Vinylsulfone, MW 2000 is a phospholipid PEG which can self-assemble to form lipid bilayer in water. The polymer can be used to encapsulate therapeutics, such as nucleic acid (mRNA/DNA) or protein, in drug delivery system. The vinyl sulfone is reactive with thiol molecule via thiol-ene reaction for bioconjugation. Reagent grade, for research use only.
    DSPE-PEG-Vinylsulfone (MW 2000)
  • HY-W800649
    Aminooxy-PEG2-amine hydrochloride

    		Biochemical Assay Reagents Others
    Aminooxy-PEG2-amine hydrochloride is an aqueous soluble crosslinker. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond, if a reductant is used, it will form a hydroxylamine linkage. The amino group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term.
    Aminooxy-PEG2-amine hydrochloride
  • HY-W440907
    DSPE-PEG-Vinylsulfone (MW 5000)

    		Biochemical Assay Reagents Others
    DSPE-PEG-Vinylsulfone, MW 5000 is a viniyl sulfone PEG lipid which can be used for bioconjugation with cysteine or other thiol molecule through thiol-ene reaction. The polymer is a self-assembling reagetn which forms lipid bilayer in water and can be used as drug carrier to delivery therapeutic agents, such as mRNA or DNA vaccine. Reagent grade, for research use only.
    DSPE-PEG-Vinylsulfone (MW 5000)
  • HY-W441011
    DSPE-NHS

    		Biochemical Assay Reagents Liposome Neurological Disease Inflammation/Immunology Cancer
    DSPE-NHS is a bioconjugation phospholipid molecule with two hydrophobic lipid tails. DSPE-NHS is a self-assembling reagent which forms lipid bilayer in aqueous solution. The NHS-ester is reactive with N-terminal of protein/peptide or other amine molecule to form a stable amide linkage. DSPE-NHS labels antibodies. DSPE-NHS can be used to prepare liposomes as agent nanocarrier .
    DSPE-NHS
  • HY-W190766
    dPEG(R)8-SATA

    S-Acetyl-dPEG(R)8-NHS ester; Polyethylene glycol

    		 Biochemical Assay Reagents
    dPEG(R)8-SATA (S-Acetyl-dPEG(R)8-NHS ester) is a bioconjugation reagent with excellent biocompatibility and high selectivity. dPEG(R)8-SATA can be used to label and cross-link biomolecules and promote the interaction between biomolecules. dPEG(R)8-SATA plays an important role in bioimaging and compound delivery systems.
    dPEG(R)8-SATA
  • HY-151818
    12-Azido-dodecanoyl-OSu

    		ADC Linker Others
    12-Azido-dodecanoyl-OSu is a click chemistry reagent containing an azide group. 12-Azido-dodecanoyl-OSu can be used as a hydrophobic bioconjugation linker. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    12-Azido-dodecanoyl-OSu
  • HY-W190737
    NHS-S-S-dPEG4-biotin (cleavable)

    		Biochemical Assay Reagents
    NHS-SS-dPEG4-biotin (cleavable) is a biodegradable crosslinker with efficient bioconjugation activity. NHS-SS-dPEG4-biotin (cleavable) can effectively connect biomolecules, optimize the efficiency of biolabeling, and be used in targeted compound delivery systems. NHS-SS-dPEG4-biotin (cleavable) can also play an important role in protein engineering and fluorescence imaging.
    NHS-S-S-dPEG4-biotin (cleavable)
  • HY-W800833
    Benzyl N-[2-(prop-2-enamido)ethyl]carbamate

    		Biochemical Assay Reagents Others
    Benzyl N-[2-(prop-2-enamido)ethyl]carbamate is a short aliphatic linker featuring a Cbz-protected amine and an acrylamide. Acrylamide is a Michael acceptor which is a good Michael acceptor which can be used in thiol-based bioconjugation or polymerization. Meanwhile, the Cbz protecting group can be removed using Pd-C hydrogenation to reveal a free amine that can participate in a wide variety of reactions such as couplings or reductive amination.
    Benzyl N-[2-(prop-2-enamido)ethyl]carbamate
  • HY-118112
    4-N-Maleimidobenzoicacid-NHS

    		Biochemical Assay Reagents Others
    4-N-Maleimidobenzoicacid-NHS is a PEG linker that finds utility in bioconjugation endeavors and protein labeling ventures. Specifically designed for selective reaction with thiol groups, the maleimide group establishes covalent linkages, thereby facilitating the coupling of proteins, peptides, or diverse molecules to thiol-bearing biomolecules. The NHS ester is able to react specifically and efficiently with primary amines (e.g. the side chain of lysine residues or aminosilane-coated surfaces) at neutral or slightly basic conditions to form a covalent bond.
    4-N-Maleimidobenzoicacid-NHS
  • HY-151692
    18-Azido-stearic acid

    		ADC Linker Others
    18-Azido-stearic acid is a click chemistry reagent containing an azide group. 18-Azido-stearic acid can be used as a hydrophobic bioconjugation linker (using N-Myristoyltransferase) that can be further modified at the azido-position using Click-chemistry . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    18-Azido-stearic acid
  • HY-151640
    Fmoc-DAP-N3

    		ADC Linker Others
    Fmoc-DAP-N3 is a click chemistry reagent containing an azide group. Fmoc-DAP-N3 is a short, linear spacer molecule with Fmoc protected amino function. Fmoc-DAP-N3 can be used in click conjugation and amid bond formation either with small molecules or for bioconjugation with proteins and antibodies . It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
    Fmoc-DAP-N3
  • HY-151655
    11-Azidoundecanoic acid

    		ADC Linker Others
    11-Azidoundecanoic acid is a click chemistry reagent containing an azide group. 11-Azidoundecanoic acid acts as a hydrophobic bioconjugation linker that can be further modified at the azido-position using Staudinger ligation or Click-chemistry. 11-Azidoundecanoic acid is substrate of lipoic acid ligase (LpIA) for labeling . 11-Azidoundecanoic acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    11-Azidoundecanoic acid

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