cadmium

By Targets:	Bacterial (1) Biochemical Assay Reagents (2) CMV (1) Endogenous Metabolite (1) Fungal (1)
By Research Areas:	Cancer (1) Cardiovascular Disease (1) Infection (3) Inflammation/Immunology (1) Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-164689

Cadmium pyrithione	Others	Cancer
Cadmium pyrithione is a metal compound that inhibits protein deubiquitinase activity. Cadmium pyrithione treatment results in significant accumulation of ubiquitinated proteins in cancer cells and primary leukemia cells. Cadmium pyrithione strongly inhibits the activity of proteasome deubiquitinase (such as USP14 and UCHL5), but has a smaller inhibitory effect on 20S proteasome activity. The anticancer activity of Cadmium pyrithione is associated with the induction of apoptosis through caspase activation. Furthermore, Cadmium pyrithione inhibition inhibited proteasome function and suppressed tumor growth in animal xenograft models .

HY-W019976

Cadmium sulfate hydrate,99.995% trace metals basis	Biochemical Assay Reagents
Cadmium sulfate hydrate,99.995% trace metals basis is a kind of biochemical reagent.

HY-167538

*sn-Glycero-3-phosphocholine 1:1 cadmium* chloride adduct**	Biochemical Assay Reagents	Others
sn-Glycero-3-phosphocholine 1:1 cadmium chloride adduct is a biochemical reagent.

HY-114881

Frequentin NSC 246118	Fungal	Infection
Frequentin, a secondary metabolite produced by Penicillium janthinellum, is influenced by environmental conditions such as cadmium nitrate and sodium chloride concentrations. In cadmium nitrate-free medium, P. janthinellum produces cyclopenin, carlosic acid, erythroskyrin, kojic acid, and patulin. At 100 ppm cadmium nitrate, it produces cyclopenin, carlosic acid, frequentin, and islandicin. In the presence of sodium chloride, frequentin is produced at 2% and 3% concentrations. These findings indicate that frequentin production is sensitive to specific environmental stressors, highlighting its potential variability under different growth conditions .

HY-128370

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Ca-DTPA trisodium salt hydrate	CMV	Infection
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication .

HY-111054

N-methyl-N-dithiocarboxyglucamine MDCG	Endogenous Metabolite	Inflammation/Immunology
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound ¹⁰⁹Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication .

HY-N9515

Diallyl tetrasulfide	Others	Neurological Disease
Diallyl tetrasulfide is an orally active diallyl polysulfide that can be isolated from garlic. Diallyl tetrasulfide has high activities to inhibit lipid peroxidation. Diallyl tetrasulfide possesses cytoprotective and antioxidant activities against cadmium-induced cytotoxicity .

HY-N1115

Tubotaiwine (+)-Tubotaiwine; NSC 306222; Tubotaiwin	Others	Cardiovascular Disease
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling .

HY-W749867

Ca(Ⅱ)-EDTA disodium dihydrate Calcium disodium EDTA dihydrate	Bacterial	Infection Others
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .

HY-W134072

Tetrasodium glutamate diacetate	Others	Others
Tetrasodium glutamate diacetate is a biodegradable chelating agent with the activity of removing polyvalent metal ions from waste activated sludge. Tetrasodium glutamate diacetate can be used as a dietary ingredient to promote the production of volatile fatty acids. Tetrasodium glutamate diacetate has potential in soil heavy metal remediation and can effectively reduce the cadmium content in soil by combining it with marigold (Tagetes patula L.) .

Cat. No.	Product Name	Type

HY-W019976

Cadmium sulfate hydrate,99.995% trace metals basis	Enzyme Substrates
Cadmium sulfate hydrate,99.995% trace metals basis is a kind of biochemical reagent.

HY-167538

*sn-Glycero-3-phosphocholine 1:1 cadmium* chloride adduct**	Cell Assay Reagents
sn-Glycero-3-phosphocholine 1:1 cadmium chloride adduct is a biochemical reagent.

HY-W749867

Ca(Ⅱ)-EDTA disodium dihydrate Calcium disodium EDTA dihydrate	Chelators
CaⅡ-EDTA disodium dihydrate (Calcium disodium EDTA dihydrate) is an orally active metal chelating reagent, exhibits bactericidal activities against periodontal pathogens Aggregatibacter actinomycetemcomitans, Prevotella intermedia and Porphyromonas gingivalis . CaⅡ-EDTA disodium dihydrate is effective chelating antidotes for lead- and cadmium poisoning .

Cat. No.	Product Name	Target	Research Area

HY-P2512A

Phytochelatin 2 (PC2) (TFA)	Peptides	Others
Phytochelatin 2 (PC2) TFA is a phytochelatin, an important heavy metal-binding peptide. Phytochelatin 2 (PC2) TFA can chelate metals, prevent metal toxicity, and maintain metal stability in the internal environment .

HY-P3322

Phytochelatin 5 PC 5	Peptides	Others
Phytochelatin 5 is metal-binding compound produced by plants. Phytochelatin 5 may reduce bioavailability of dietary toxic metals such as cadmium .

HY-P3323

Phytochelatin 6 PC 6	Peptides	Others
Phytochelatin 6 is metal-binding compound produced by plants. Phytochelatin 6 may reduce bioavailability of dietary toxic metals such as cadmium .

HY-P3322A

Phytochelatin 5 TFA PC 5 TFA	Peptides	Others
Phytochelatin 5 TFA is metal-binding compound produced by plants. Phytochelatin 5 TFA may reduce bioavailability of dietary toxic metals such as cadmium .

HY-P3323A

Phytochelatin 6 TFA PC 6 TFA	Peptides	Others
Phytochelatin 6 TFA is metal-binding compound produced by plants. Phytochelatin 6 TFA may reduce bioavailability of dietary toxic metals such as cadmium .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-114881

Frequentin NSC 246118	Structural Classification Microorganisms Antibiotics Source classification Other Antibiotics	Fungal
Frequentin, a secondary metabolite produced by Penicillium janthinellum, is influenced by environmental conditions such as cadmium nitrate and sodium chloride concentrations. In cadmium nitrate-free medium, P. janthinellum produces cyclopenin, carlosic acid, erythroskyrin, kojic acid, and patulin. At 100 ppm cadmium nitrate, it produces cyclopenin, carlosic acid, frequentin, and islandicin. In the presence of sodium chloride, frequentin is produced at 2% and 3% concentrations. These findings indicate that frequentin production is sensitive to specific environmental stressors, highlighting its potential variability under different growth conditions .

HY-111054

N-methyl-N-dithiocarboxyglucamine MDCG	Structural Classification Natural Products Classification of Application Fields Source classification Endogenous metabolite Inflammation/Immunology Disease Research Fields	Endogenous Metabolite
N-methyl-N-dithiocarboxyglucamine (MDCG) mobilizes and promotes excretion of metallothione-bound ¹⁰⁹Cd. N-methyl-N-dithiocarboxyglucamine shows effects on acute and chronic Cd intoxication .

HY-N9515

Diallyl tetrasulfide	Structural Classification Natural Products Source classification Allium sativum L. Plants Amaryllidaceae	Others
Diallyl tetrasulfide is an orally active diallyl polysulfide that can be isolated from garlic. Diallyl tetrasulfide has high activities to inhibit lipid peroxidation. Diallyl tetrasulfide possesses cytoprotective and antioxidant activities against cadmium-induced cytotoxicity .

HY-N1115

Tubotaiwine (+)-Tubotaiwine; NSC 306222; Tubotaiwin	Apocynaceae Structural Classification Alkaloids Other Alkaloids Source classification Hunteria zeylanica Plants	Others
Tubotaiwine ((+)-Tubotaiwine), an alkaloid, has beneficial effect on cadmium (Cd) induced hypertension in rats. Tubotaiwine regulates systolic, diastolic and mean arterial blood pressure of the Cd exposed rats. Tubotaiwine reduces arterial stiffness, inhibits of oxidative stress and increases vascular remodeling .

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