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Results for "

cap analog

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Nucleoside Antimetabolite/Analog (2) DNA/RNA Synthesis (16) Endogenous Metabolite (3) Polo-like Kinase (PLK) (1)
By Research Areas:	Cancer (3) Infection (2)
Oligonucleotides:	mRNA (4) Cap Analogs (17) Cap 1 (7) Cap 0 (5)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Oligonucleotides

Targets Recommended: Nucleoside Antimetabolite/Analog

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-145974A

m7GpppAmpG ammonium m7G(5')ppp(5')(2'OMeA)pG ammonium	DNA/RNA Synthesis	Others
m7GpppAmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90% .

HY-141472

7-Methylguanosine 5'-diphosphate sodium 7-Methyl-GDP sodium; m7GDP sodium	Endogenous Metabolite	Others
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

HY-145969A

β-S-ARCA triammonium	Others	Cancer
β-S-ARCA (triammonium) is a mRNA 7-methylguanosine (m ⁷G) cap analog carrying a phosphorothioate (PS) moiety. mRNA incorporating β-S-ARCA (triammonium) can prolong cellular half-life and increase protein expression. β-S-ARCA (triammonium) can be used in research of mRNA-based anti-cancer vaccines .

HY-145974

m7GpppAmpG m7G(5')ppp(5')(2'OMeA)pG	DNA/RNA Synthesis	Others
m7GpppAmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90% .

HY-145977

m7GpppGmpG	DNA/RNA Synthesis	Others
m7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .

HY-145977A

m7GpppGmpG ammonium	DNA/RNA Synthesis	Others
m7GpppGmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .

HY-131736

3'-O-Bn-GTP 3'-O-Benzyl-5'-O-guanosine triphosphate	Others	Others
3'-O-Bn-GTP (CAP-164) is an analog of GTP. 3'-O-Bn-GTP has a higher stability against esterases .

HY-123702

CAP-53194	Polo-like Kinase (PLK)	Cancer
CAP-53194 is a selective Plk1 inhibitor with potential anticancer activity. CAP-53194 was identified by a high-throughput virtual screening approach using molecular docking, showing 100-fold selectivity for Plk1 over Plk2-4 and other cell cycle kinases. CAP-53194 is able to effectively exploit subtle differences between the binding sites of Plk1 and other Ser/Thr kinases, thereby enhancing their inhibitory effects. CAP-53194 meets the Lipinski compound analog criteria and passes other ADMET filters, indicating good compound compatibility. CAP-53194 belongs to a new class of potential Plk1 inhibitors suitable for subsequent compound development and testing .

HY-150144

Uracil-m7GpppAmpG ammonium	DNA/RNA Synthesis	Others
Uracil-m7GpppAmpG ammonium is a cap analog that can be used for mRNA synthesis.

HY-145913

m7GpppApG	DNA/RNA Synthesis	Others
m7GpppApG is a trinucleotide mRNA 5' cap analog that can be used for RNA synthesis in vitro .

HY-145913A

m7GpppApG triammonium	DNA/RNA Synthesis	Others
m7GpppApG triammonium is a trinucleotide mRNA 5' cap analog that can be used for RNA synthesis in vitro .

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA	DNA/RNA Synthesis Endogenous Metabolite	Others
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-145975

m7Gpppm6AmpG	DNA/RNA Synthesis	Others
m7Gpppm6AmpG is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG can be used for RNA synthesis in vitro .

HY-139101A

Guanosine 5'-triphosphate-5'-adenosine triammonium GpppA triammonium	DNA/RNA Synthesis Endogenous Metabolite	Others
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog .

HY-145975A

m7Gpppm6AmpG ammonium	DNA/RNA Synthesis	Others
m7Gpppm6AmpG ammonium is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro .

HY-158772

m7G(5')ppp(5')(2'OMeA)pU ammonium	DNA/RNA Synthesis	Others
m7G(5')ppp(5')(2'OMeA)pU ammonium is a cap analog that can be used for in vitro transcription of mRNA.

HY-139100

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA	DNA/RNA Synthesis	Infection
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-139098

7-Methyl-diguanosine triphosphate m7Gp3G	DNA/RNA Synthesis	Others
7-Methyl-diguanosine triphosphate (m7Gp3G) is a cap analog that can incorporated into mRNA. 7-Methyl-diguanosine triphosphate is involved in translation and mRNA degradation in mammalian cells .

HY-139100B

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium m7GpppA diammonium	DNA/RNA Synthesis	Infection
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-158819

m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium	DNA/RNA Synthesis	Others
m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium is a cap analog that can be used for in vitro transcription of mRNA.

HY-21586B

7-Methyl-guanosine-5'-triphosphate sodium m7GTP sodium	Nucleoside Antimetabolite/Analog	Others
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

HY-157339

MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite	Nucleoside Antimetabolite/Analog	Others
MMT-2'-O-Methyl adenosine (n-bz) CED phosphoramidite (compound 1) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies .

HY-155337

eIF4E-IN-6	Others	Cancer
eIF4E-IN-6(compound 4b) is a GMP analogs synthesized to targeteIF4Eand restrain its binding to cap mRNA.eIF4E-IN-6shows cell cytotoxicity against Caco-2, HepG-2,and MCF-7 cells, withIC₅₀values of 31, 27, and 21 μM, respectively .

m7GpppAmpG ammonium m7G(5')ppp(5')(2'OMeA)pG ammonium	Gene Sequencing and Synthesis
m7GpppAmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90% .

3'-O-Me-m7G(5')ppp(5')A ARCA cap	Biochemical Assay Reagents
3'-O-Me-m7G(5')ppp(5')A (ARCA cap), anti-reverse cap analog, has a special RNA cap structure. Is a common feature of the mRNA of some RNA viruses and eukaryotes. RNA cap structures serve as signals for translation initiation .

m7Gpppm6AmpG ammonium	Gene Sequencing and Synthesis
m7Gpppm6AmpG ammonium is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro .

7-Methyl-guanosine-5'-triphosphate sodium m7GTP sodium	Gene Sequencing and Synthesis
7-Methyl-guanosine-5'-triphosphate (m7GTP) sodium is a guanosine 5'-phosphate. 7-Methyl-guanosine-5'-triphosphate sodium phosphorothioate analog is a potent cap-dependent translation inhibitor .

m7GpppGmpG ammonium	Gene Sequencing and Synthesis
m7GpppGmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .

Uracil-m7GpppAmpG ammonium	Gene Sequencing and Synthesis
Uracil-m7GpppAmpG ammonium is a cap analog that can be used for mRNA synthesis.

Guanosine 5'-triphosphate-5'-adenosine GpppA	Gene Sequencing and Synthesis
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA	Gene Sequencing and Synthesis
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

7-Methyl-diguanosine triphosphate m7Gp3G	Gene Sequencing and Synthesis
7-Methyl-diguanosine triphosphate (m7Gp3G) is a cap analog that can incorporated into mRNA. 7-Methyl-diguanosine triphosphate is involved in translation and mRNA degradation in mammalian cells .

7-Methylguanosine 5'-diphosphate sodium 7-Methyl-GDP sodium; m7GDP sodium	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	Endogenous Metabolite
7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues .

Guanosine 5'-triphosphate-5'-adenosine GpppA	Structural Classification Natural Products Classification of Application Fields Source classification Other Diseases Endogenous metabolite Disease Research Fields	DNA/RNA Synthesis Endogenous Metabolite
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

Cat. No.	Product Name		Classification

HY-145974A

m7GpppAmpG ammonium m7G(5')ppp(5')(2'OMeA)pG ammonium		Cap Analogs Cap 1
m7GpppAmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90% .

HY-153108

3'-O-Me-m7G(5')ppp(5')A ARCA cap		Cap Analogs
3'-O-Me-m7G(5')ppp(5')A (ARCA cap), anti-reverse cap analog, has a special RNA cap structure. Is a common feature of the mRNA of some RNA viruses and eukaryotes. RNA cap structures serve as signals for translation initiation .

HY-145969

β-S-ARCA		Cap Analogs Cap 0
β-S-ARCA is a mRNA 7-methylguanosine (m ⁷G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines .

HY-145974

m7GpppAmpG m7G(5')ppp(5')(2'OMeA)pG		Cap Analogs Cap 1
m7GpppAmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 90% .

HY-145977

m7GpppGmpG		Cap Analogs Cap 1
m7GpppGmpG is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .

HY-145977A

m7GpppGmpG ammonium		Cap Analogs Cap 1
m7GpppGmpG ammonium is a trinucleotide 5′ cap analog with the capping efficiencies for the obtained RNAs of 86% .

HY-150144

Uracil-m7GpppAmpG ammonium		Cap Analogs Cap 1
Uracil-m7GpppAmpG ammonium is a cap analog that can be used for mRNA synthesis.

HY-145913

m7GpppApG		Cap Analogs Cap 0
m7GpppApG is a trinucleotide mRNA 5' cap analog that can be used for RNA synthesis in vitro .

HY-139101

Guanosine 5'-triphosphate-5'-adenosine GpppA		Cap Analogs
Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog .

HY-145975

m7Gpppm6AmpG		Cap Analogs Cap 1
m7Gpppm6AmpG is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG can be used for RNA synthesis in vitro .

HY-139101A

Guanosine 5'-triphosphate-5'-adenosine triammonium GpppA triammonium		Cap Analogs
Guanosine 5'-triphosphate-5'-adenosine (GpppA) triammonium, a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine triammonium is a fluorescent substrate analog .

HY-145975A

m7Gpppm6AmpG ammonium		Cap Analogs Cap 1
m7Gpppm6AmpG ammonium is a trinucleotide mRNA 5’ cap analogs. m7Gpppm6AmpG ammonium can be used for RNA synthesis in vitro .

HY-158772

m7G(5')ppp(5')(2'OMeA)pU ammonium		Cap Analogs
m7G(5')ppp(5')(2'OMeA)pU ammonium is a cap analog that can be used for in vitro transcription of mRNA.

HY-139100

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine m7GpppA		Cap Analogs Cap 0
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-139098

7-Methyl-diguanosine triphosphate m7Gp3G		Cap Analogs Cap 0
7-Methyl-diguanosine triphosphate (m7Gp3G) is a cap analog that can incorporated into mRNA. 7-Methyl-diguanosine triphosphate is involved in translation and mRNA degradation in mammalian cells .

HY-139100B

N7-Methyl-guanosine-5'-triphosphate-5'-adenosine diammonium m7GpppA diammonium		Cap Analogs Cap 0
N7-Methyl-guanosine-5'-triphosphate-5'-adenosine (m7GpppA) diammonium is a dinucleotide cap analog that can be used for in vitro RNA transcription .

HY-158819

m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium		Cap Analogs
m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium is a cap analog that can be used for in vitro transcription of mRNA.

HY-164059

LZCap AG(3'Acm) mCherry mRNA		mRNA
mCherry is a red fluorescent protein the derived from Discosoma sp.. mCherry has excitation/emission wavelengths of 587 nm/610 nm. LZCap AG(3'Acm) mCherry mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog from a linear template. LZCap AG(3'Acm) generates a Cap1 structure mRNA post-transcription, providing more efficient and stable expression compared to Cap0 and other commercially available Cap1 structures. LZCap AG(3'Acm) mCherry mRNA contains poly A, optimized 5'UTR, and 3'UTR structures to improve mRNA stability and promote translation efficiency, resulting in enhanced expression. Upon entering cells, LZCap AG(3'Acm) mCherry mRNA expresses red fluorescence, suitable for experiments related to mRNA delivery, translation efficiency, transfection efficiency, and in vivo imaging.

HY-164060

LZCap AG(3'Acm) RLuc mRNA		mRNA
Renilla luciferase (RLuc) is a novel luciferase enzyme with a size of 36 kD. RLuc catalyzes the oxidation reaction of coelenterazine under oxygen to emit fluorescence (maximum wavelength 480 nm). LZCap AG(3'Acm) RLuc mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog from a linear template. This mRNA is suitable for experiments related to mRNA delivery, translation efficiency, transfection efficiency, and in vivo imaging.

HY-164058

LZCap AG(3'Acm) RFP mRNA		mRNA
Red fluorescent protein (RFP) is a protein isolated from the Pacific anemone (Discosoma sp.) that can emit red fluorescence under ultraviolet light. RFP can be excited by the 488 nm or 532 nm laser line and is optimally detected at 588 nm. LZCap AG(3'Acm) RFP mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog. This mRNA is suitable for experiments related to mRNA delivery, translation efficiency, transfection efficiency, and in vivo imaging.

HY-164061

LZCap AG(3'Acm) GLuc mRNA		mRNA
Gaussia luciferase (GLuc) is the smallest known naturally secreted luciferase enzyme (20 kD) in vivo. When conducting fluorescence reporter experiments with Gaussia luciferase, detection can be directly performed using cell culture supernatant. This luciferase enzyme catalyzes the oxidation of coelenterazine to emit light (480 nm) without requiring ATP. LZCap AG(3'Acm) GLuc mRNA is synthesized and purified in a one-step transcription process using T7 RNA polymerase and LZCap AG(3'Acm) cap analog from a linear template. This mRNA is suitable for experiments related to mRNA delivery, translation efficiency, and transfection efficiency.

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cap analog

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