Search Result

Results for "

citalopram

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (3) Autophagy (2) Cytochrome P450 (3) Isotope-Labeled Compounds (8) Serotonin Transporter (13)
By Research Areas:	Cancer (7) Neurological Disease (18)

Inhibitors & Agonists

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-121203

*Citalopram* Maximum Cited Publications 6 Publications Verification	Serotonin Transporter	Neurological Disease Cancer
Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission .

HY-B1287

Citalopram hydrobromide Maximum Cited Publications 6 Publications Verification (±)-citalopram hydrobromide; Lu 10-171	Serotonin Transporter Autophagy	Neurological Disease Cancer
Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC₅₀ of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC₅₀ of 14 nM. Antidepressant effect .

HY-121203S

Citalopram-d4 hydrobromide	Isotope-Labeled Compounds Serotonin Transporter	Neurological Disease
Citalopram-d₄ (hydrobromide) is the deuterium labeled Citalopram hydrobromide. Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI)[1].

HY-110289

*(R)-Citalopram* oxalate**	Serotonin Transporter 5-HT Receptor	Neurological Disease
(R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram; HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism .

HY-121203R

Citalopram (Standard)	Serotonin Transporter	Neurological Disease Cancer
Citalopram (Standard) is the analytical standard of Citalopram. This product is intended for research and analytical applications. Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission .

HY-121203S3

Citalopram-d6	Isotope-Labeled Compounds	Others
Citalopram-d₆ is the deuterium labeled Citalopram[1].

HY-121203S4

Citalopram-d3 hydrochloride	Serotonin Transporter Isotope-Labeled Compounds	Neurological Disease Cancer
Citalopram-d₃ hydrochloride is deuterated labeled Citalopram (HY-121203). Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission .

HY-B1287R

Citalopram hydrobromide (Standard) (±)-citalopram hydrobromide(Standard); Lu 10-171 (Standard)	Serotonin Transporter Autophagy	Neurological Disease Cancer
Citalopram (hydrobromide) (Standard) is the analytical standard of Citalopram (hydrobromide). This product is intended for research and analytical applications. Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC₅₀ of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC₅₀ of 14 nM. Antidepressant effect .

HY-121203S1

Citalopram-d6 oxalate	Isotope-Labeled Compounds	Others
Citalopram-d6 oxalate is the deuterium labeled Citalopram oxalate .

HY-121203A

Citalopram oxalate	Others	Neurological Disease
Citalopram oxalate is a serotonin uptake inhibitor that serves as an antidepressant, effectively reducing ethanol uptake in alcoholics and offering a preferable option for depressed patients experiencing tardive dyskinesia compared to tricyclic antidepressants, which may worsen this condition.

HY-110289R

*(R)-Citalopram* oxalate (Standard)**	Serotonin Transporter 5-HT Receptor	Neurological Disease
(R)-Citalopram (oxalate) (Standard) is the analytical standard of (R)-Citalopram (oxalate). This product is intended for research and analytical applications. (R)-Citalopram oxalate is an anticonvulsant, antidepressant and muscle relaxant. (R)-Citalopram oxalate is at least 20-fold weaker than S-citalopram (Escitalopram; HY-14258) as inhibitor of the 5-HT transporter (SERT). (R)-Citalopram oxalate functionally antagonises S-citalopram in vivo and in vitro. (R)-Citalopram oxalate has an effect on the association of Escitalopram with the high affinity primary site, and on its dissociation from the 5-HT transporter, via an allosteric mechanism .

HY-110289S1

*(R)-Citalopram-d4 oxalate*	Isotope-Labeled Compounds	Others
(R)-Citalopram-d₄ (oxalate) is deuterium labeled (R)-Citalopram Oxalate.

HY-14258

Escitalopram 3 Publications Verification (S)-citalopram; (S)-(+)-citalopram	Serotonin Transporter	Neurological Disease
Escitalopram ((S)-Citalopram), the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a K_i of 0.89 nM. Escitalopram has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram is an antidepressant for the research of major depression .

HY-143931S

*N-Desmethyl citalopram-d4 oxalate*	Isotope-Labeled Compounds	Others
N-Desmethyl citalopram-d₄ (oxalate) is the deuterium labeled N-Desmethyl citalopram oxalate[1].

HY-14258A

Escitalopram oxalate 3 Publications Verification (S)-citalopram oxalate; (S)-(+)-citalopram oxalate	Serotonin Transporter	Neurological Disease Cancer
Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a K_i of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression .

HY-14258AR

Escitalopram oxalate (Standard) (S)-citalopram oxalate (Standard); (S)-(+)-citalopram oxalate (Standard)	Serotonin Transporter	Neurological Disease Cancer
Escitalopram (oxalate) (Standard) is the analytical standard of Escitalopram (oxalate). This product is intended for research and analytical applications. Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a K_i of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression .

HY-14258AS1

Escitalopram-d4 oxalate (S)-citalopram-d₄ oxalate; (S)-(+)-citalopram-d₄ oxalate	Isotope-Labeled Compounds Serotonin Transporter	Neurological Disease
Escitalopram-d₄ (oxalate) is deuterium labeled Escitalopram (oxalate). Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2].

HY-113739

Desmethylcitalopram hydrochloride DCIT hydrochloride	Cytochrome P450	Neurological Disease
Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC₅₀s of 39.5 and 53.5 μM .

HY-113739A

(S)-Desmethylcitalopram (S)-DCIT	Cytochrome P450	Neurological Disease
(S)-Desmethylcitalopram is the isomer of Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6，-2C19 with IC₅₀s of 39.5 and 53.5 μM .

HY-113739S1

Desmethylcitalopram-d4 hydrochloride DCIT-d₄ hydrochloride	Cytochrome P450 Isotope-Labeled Compounds	Neurological Disease
Desmethylcitalopram-d₄ hydrochloride is deuterated labeled Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC₅₀s of 39.5 and 53.5 μM .

HY-14258AS

Escitalopram-d6 oxalate	Serotonin Transporter	Neurological Disease
Escitalopram-d₆ (oxalate) is the deuterium labeled Escitalopram oxalate. Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2].

HY-160921

Capeserod SL65.0155 free base	5-HT Receptor	Neurological Disease
Capeserod (SL65.0155 free base) is an agonist for serotonin receptor (5-HT receptor), with a K_i of 0.6 nM for 5-HT₄ receptor. Capeserod enhances expression of phopshorilated cAMP-response element binding protein (p-CREB), vascular endothelium growth factor (VEGF), brain-derived neurotrophic factor (BDNF) and B cell lymphoma-2 (Bcl-2) proteins in hippocampus, and exhibits antidepressant-like efficacy in Wistar rats models .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-14258

Escitalopram 3 Publications Verification (S)-citalopram; (S)-(+)-citalopram	Natural Products Source classification Endogenous metabolite	Serotonin Transporter
Escitalopram ((S)-Citalopram), the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a K_i of 0.89 nM. Escitalopram has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram is an antidepressant for the research of major depression .

Cat. No.	Product Name	Chemical Structure

HY-121203S

Citalopram-d4 hydrobromide
Citalopram-d₄ (hydrobromide) is the deuterium labeled Citalopram hydrobromide. Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI)[1].

HY-121203S3

Citalopram-d6
Citalopram-d₆ is the deuterium labeled Citalopram[1].

HY-121203S4

Citalopram-d3 hydrochloride
Citalopram-d₃ hydrochloride is deuterated labeled Citalopram (HY-121203). Citalopram is a racemate mixture of the active S(+)-enantiomer (Escitalopram; HY-14258) and R(-)-enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission .

HY-121203S1

Citalopram-d6 oxalate
Citalopram-d6 oxalate is the deuterium labeled Citalopram oxalate .

HY-110289S1

*(R)-Citalopram-d4 oxalate*
(R)-Citalopram-d₄ (oxalate) is deuterium labeled (R)-Citalopram Oxalate.

HY-143931S

*N-Desmethyl citalopram-d4 oxalate*
N-Desmethyl citalopram-d₄ (oxalate) is the deuterium labeled N-Desmethyl citalopram oxalate[1].

HY-14258AS1

Escitalopram-d4 oxalate
Escitalopram-d₄ (oxalate) is deuterium labeled Escitalopram (oxalate). Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2].

Escitalopram-d4 oxalate

Escitalopram-d₄ (oxalate) is deuterium labeled Escitalopram (oxalate). Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2].

HY-113739S1

Desmethylcitalopram-d4 hydrochloride
Desmethylcitalopram-d₄ hydrochloride is deuterated labeled Desmethylcitalopram hydrochloride (HY-113739). Desmethylcitalopram (DCIT) hydrochloride is the active metabolite of Citalopram (HY-121203). Desmethylcitalopram has antidepressant effects. Desmethylcitalopram also inhibits cytochrome P450-2D6, -2C19 with IC₅₀s of 39.5 and 53.5 μM .

HY-14258AS

Escitalopram-d6 oxalate
Escitalopram-d₆ (oxalate) is the deuterium labeled Escitalopram oxalate. Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2].

Escitalopram-d6 oxalate

Escitalopram-d₆ (oxalate) is the deuterium labeled Escitalopram oxalate. Escitalopram ((S)-Citalopram) oxalate, the S-enantiomer of racemic Citalopram, is a selective serotonin reuptake inhibitor (SSRI) with a Ki of 0.89 nM. Escitalopram oxalate has ∼30 fold higher binding affinity than its R(-)-enantiomer and shows selectivity over both dopamine transporter (DAT) and norepinephrine transporter (NET). Escitalopram oxalate is an antidepressant for the research of major depression[1][2].

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks