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decomposition

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52

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2

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7

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1

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8

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3

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-W009350
    Diazolidinyl urea

    		Bacterial Infection
    Diazolidinyl urea is a broad-spectrum preservative commonly used in cosmetics. Diazolidinyl urea exerts antibacterial effects by decomposing and releasing formaldehyde. Diazolidinyl urea is effective against most contaminating microorganisms, especially Pseudomonas .
    Diazolidinyl urea
  • HY-114524
    (E)-4-Oxo-2-nonenal
    1 Publications Verification

    4-ONE

    		 TRP Channel Cardiovascular Disease
    (E)-4-Oxo-2-nonenal (4-ONE) is one of the major hemolytic decomposition products of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a major product of the FeII-mediated breakdown of lipid hydroperoxides. (E)-4-Oxo-2-nonenal is a potent transient receptor potential ankyrin 1 (TRPA1) agonist .
    (E)-4-Oxo-2-nonenal
  • HY-B0967
    Phthalylsulfacetamide

    		Bacterial Infection
    Phthalylsulfacetamide is a sulfa drug, after oral administration, slowly decompose in the intestine,and release sulfacetamide ,generating antibacterial effect.
    Phthalylsulfacetamide
  • HY-W066915
    Nortropine hydrochloride

    Nortropenol hydrochloride

    		 Drug Intermediate Others
    Nortropine hydrochloride can be isolated from the Convolvulus subhirsutus alkaloid and is an intermediate in the decomposition and reaction of tropine to produce succinic acid .
    Nortropine hydrochloride
  • HY-W087905
    2,3-Dimethyl-2,3-diphenylbutane

    		Biochemical Assay Reagents Others
    2,3-Dimethyl-2,3-diphenylbutane is a minor product formed during the thermal decomposition of dicumyl peroxide (DCP) in cumene, generated through radical coupling reactions. As an initiator capable of producing free radicals, 2,3-dimethyl-2,3-diphenylbutane promotes cross-linking or decomposition processes via initiating free radical reactions in fields such as polymer polymerization (e.g., modification of polyphenylene oxide processing), organic synthesis (e.g., DCP decomposition reactions), and coal processing (e.g., oxidation stabilization of coal tar pitch), thereby enhancing material properties or reaction efficiency .
    2,3-Dimethyl-2,3-diphenylbutane
  • HY-121345
    Homobaldrinal

    		Drug Metabolite Neurological Disease Cancer
    Homobaldrinal is a decomposition product of Valepotriate (HY-N0718). Homobaldrinal exhibits genotoxic activity in the Salmonella/microsome test .
    Homobaldrinal
  • HY-157376
    Casein Agar

    		Biochemical Assay Reagents Others
    Casein Agar can be used for casein decomposition test of Bacillus cereus. The composition of 1 liter of Casein Agar contains contains: 10.0 g casein, 3.0 g beef infusion powder, 5.0 g sodium chloride, 2.0 g dipotassium hydrogen phosphate and 15.0 g agar .
    Casein Agar
  • HY-155386
    Peroxynitrite sodium

    		Biochemical Assay Reagents Others
    Peroxynitrite sodium is a highly reactive nitroxide species that can decompose at physiological pH .
    Peroxynitrite sodium
  • HY-P2984
    Adenosine triphosphatase

    		Endogenous Metabolite Metabolic Disease
    Adenosine triphosphatase is an enzyme that catalyzes the decomposition of ATP into ADP and a free phosphate ion (Pi) .
    Adenosine triphosphatase
  • HY-120374
    V-PYRRO/NO

    		Biochemical Assay Reagents Metabolic Disease
    V-PYRRO/NO is a NO donor in vivo. Following hepatic metabolism, it spontaneously decomposes with a half-life of 3 seconds to liberate NO.
    V-PYRRO/NO
  • HY-P2726
    Aldolase, Rabbit muscle

    Fructose-diphosphate aldolase

    		 Endogenous Metabolite Metabolic Disease
    Aldolase, Rabbit muscle is a glycolytic enzyme and a component of the VATPase complex. Aldolase causes fructose 1, 6-diphosphate to decompose into dihydroxyacetone and glyceraldehyde 3-phosphate .
    Aldolase, Rabbit muscle
  • HY-121066
    Dehydrorotenone

    		Others Others
    Dehydrorotenone is a rotenone analog that is resistant to alkali decomposition. When treated with alkaline solution or alkaline solution containing zinc, dehydrorotenone can absorb 2 molecules of water and convert into acid solution.
    Dehydrorotenone
  • HY-118116
    bicyclo-PGE2

    bicyclo-PGEM; bicyclo-Prostaglandin E2

    		 Drug Metabolite Others
    bicyclo-PGE2 (bicyclo-PGEM) is a stable decomposition product of PGE2 and 13, 14-dihydro-15-ketone PGE2 .
    bicyclo-PGE2
  • HY-W011816
    1,2-Hexadecanediol

    		Biochemical Assay Reagents Others
    1,2-Hexadecanediol is a reducing agent. 1,2-Hexadecanediol facilitates the decomposition of the metal-organic precursor, forms an intermediate Co 2+Fe 3+-oleate complex .
    1,2-Hexadecanediol
  • HY-Y1422
    Triacylglycerol lipase

    Alkaline lipase

    		 Lipase Metabolic Disease
    Triacylglycerol lipase is an enzyme catalyzing the hydrolysis of triacylglycerol. Triacylglycerol lipase promotes fat decomposition, providing energy and lipid precursors for cells. Triacylglycerol lipase is used in the research of metabolic diseases such as diabetes and obesity .
    Triacylglycerol lipase
  • HY-113110
    Cysteinylglycine

    		Endogenous Metabolite Neurological Disease Cancer
    Cysteinylglycine is a dipeptide produced by the decomposition of extracellular glutathione catalyzed by γ-glutamyl transpeptidase. Cysteinylglycine is a highly reactive metabolite. Cysteinylglycine is currently mainly used in neurodegenerative diseases and breast cancer research .
    Cysteinylglycine
  • HY-N13024
    Radulone A

    		Fungal Infection
    Radulone A is a secondary metabolite, which can be isolated from the wood decomposing fungus Granulobasidium vellereum. Radulone A inhibits spore germination of Phlebiopsis gigantea, Coniophora puteana and Heterobasidion occidentale, with concentrations of 10 µM, 500 µM and 100 µM, respectively .
    Radulone A
  • HY-E70005D
    Collagenase IV, Clostridium histolytica
    1 Publications Verification

    Collagenase, Type IV

    		 MMP Others
    Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin.
    Collagenase IV, Clostridium histolytica
  • HY-165097
    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

    15(S)-HpETE-SAPC; 15(S)-Hydroperoxyeicostetraenoic acid-SAPC

    		 Reactive Oxygen Species (ROS) Others
    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC (15(S)-HpETE-SAPC) is a compound studied for the cytotoxicity of phosphatidylcholine hydroperoxides. Its cytotoxicity is exerted through the decomposition of hydroperoxides to produce toxic compounds.
    1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
  • HY-W040240
    (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one

    		Endogenous Metabolite Metabolic Disease
    (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one is an endogenous metabolite generated by the thermal decomposition of β-D-glucopyranose and further isomerization .
    (3S,4R,5S)-1,3,4,5,6-Pentahydroxyhexan-2-one
  • HY-W010056
    Diethyl fumarate
    1 Publications Verification

    		 Biochemical Assay Reagents Neurological Disease Inflammation/Immunology
    Diethyl fumarate is a decomposition product of Malathion 9 (a pesticide) and reactant in the Diels-Alder reaction. Diethyl fumarate is a reputed skin irritant. Diethyl fumarate can causes non-immunologic contact urticaria on skin. Diethyl fumarate and Curcumin (HY-N0005) hybridize to exert neuroprotective effects .
    Diethyl fumarate
  • HY-157359
    Bacterial Organophosphorus Medium

    		Biochemical Assay Reagents Others
    Bacterial Organophosphorus Medium can be used to determine the efficiency of phosphorus bacteria in decomposing organic phosphorus in phosphorus bacteria fertilizers. Bacterial Organophosphorus Medium ingredients include glucose, ammonium sulfate, yeast extract, sodium chloride, potassium chloride, magnesium sulfate, ferrous sulfate, manganese sulfate, lecithin, calcium carbonate, agar .
    Bacterial Organophosphorus Medium
  • HY-113110R
    Cysteinylglycine (Standard)

    		Endogenous Metabolite Neurological Disease Cancer
    Cysteinylglycine (Standard) is the analytical standard of Cysteinylglycine. This product is intended for research and analytical applications. Cysteinylglycine is a dipeptide produced by the decomposition of extracellular glutathione catalyzed by γ-glutamyl transpeptidase. Cysteinylglycine is a highly reactive metabolite. Cysteinylglycine is currently mainly used in neurodegenerative diseases and breast cancer research .
    Cysteinylglycine (Standard)
  • HY-172548
    Docosahexaenoyl-L-carnitine chloride

    		Endogenous Metabolite Metabolic Disease
    Docosahexaenoyl-L-carnitine chloride is a long-chain acylcarnitine composed of Docosahexaenoic acid (HY-B2167) and L-carnitine (HY-B0399). Docosahexaenoyl-L-carnitine chloride is transported into mitochondria for β -oxidation and decomposition under the action of carnitine palmitoyltransferase I (CPT I) and others. Docosahexaenoyl-L-carnitine chloride is promising for research of diseases related to fatty acid metabolism .
    Docosahexaenoyl-L-carnitine chloride
  • HY-131697
    FeTPPS

    		NO Synthase Apoptosis Inflammation/Immunology
    FeTPPS, a 5,10,15,20-tetrakis (4-sulfonatophenyl) porphyrin iron III chloride peroxynitrite decomposition catalyst, possesses evident neuroprotective effects in a experimental model of spinal cord damage . FeTPPS acts as a peroxynitrite scavenger and anti-nitrating agent in vivo. FeTPPS reduces nitric oxide (NO) production and apoptosis process .
    FeTPPS
  • HY-B1335
    Pentetic acid

    Diethylenetriaminepentaacetic acid; DTPA

    		 Fluorescent Dye Others
    Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide .
    Pentetic acid
  • HY-P2753
    Sucrose phosphorylase

    SP

    		 Endogenous Metabolite Others Cancer
    Sucrose phosphorylase is a bacterial transglucosidase that catalyzes the conversion of sucrose and phosphate into α-D-glucose-1-phosphate and D-fructose. The glucosylated Sucrose phosphorylase can also be hydrolyzed into α-D-glucose, or transfer the glucoyl to the hydroxyl group of the receptor, and then decomposed into new α-D-glucoside products. The enzymatic activity of base phosphorylase to substrate and product is weak .
    Sucrose phosphorylase
  • HY-167629
    Gibberellenic acid

    		Phytohormone Drug Intermediate Others
    Gibberellenic acid is an intermediate gibberellin compound with a tetracyclic diterpenoid skeleton, and can be generated by thermal decomposition of Gibberellic acid (GA3, HY-N1964) in aqueous solution. Gibberellenic acid is thermally unstable in water and can further convert into allogibberic acid (approximately 80%) and 9-epiallogibberic acid (approximately 10%). It plays an important role in the degradation pathway and structural elucidation of Gibberellins .
    Gibberellenic acid
  • HY-135849C
    Catalase, trichoderma reesei

    		Reactive Oxygen Species (ROS) Cancer
    Catalase, Trichoderma reesei, is a catalase enzyme that catalyzes the decomposition of hydrogen peroxide (H2O2) into water (H2O) and oxygen (O2). Catalase is mainly present in peroxisomes and shuttles between the cytoplasm and peroxisomes, thereby protecting cells from oxidative damage. Abnormal activity or expression of catalase is closely related to the occurrence and development of cancer .
    Catalase, trichoderma reesei
  • HY-Y0525
    AAPH

    2,2'-Azodiisobutyramidine dihydrochloride

    		 Reactive Oxygen Species (ROS) Inflammation/Immunology
    AAPH (2,2'-Azodiisobutyramidine dihydrochloride) has an effect of radical generation. AAPH induces oxidative stress and erythrocyte hemolysis . AAPH decomposes at 37℃ to generate an alkyl radical, is used as an initiator. In the presence of oxygen, these alkyl radicals will be converted to peroxyl radicals that can cause lipid peroxidation and loss of erythrocyte membrane integrity, which could ultimately lead to hemolysis .
    AAPH
  • HY-D1746
    EDTA-AM

    EDTA acetoxymethyl ester; Ethylenediaminetetraacetic acid acetoxymethyl ester

    		 Biochemical Assay Reagents Mitosis Others
    EDTA-AM (ethylenediaminetetraacetic acid, acetoxymethyl ester) is the membrane-permeant form of the metal chelator EDTA (HY-Y0682). Live cells passively load EDTA-AM by incubating with EDTA-AM. Once internalized, cytoplasmic esterase decomposes AM esters, releasing the active ligand EDTA, which isolates metal ions within the cell. EDTA-AM induces an arrest of mitotic progression and chromosome decondensation .
    EDTA-AM
  • HY-P2860A
    Acetylcholinesterase, Electric eel

    		Cholinesterase (ChE) Neurological Disease
    Acetylcholinesterase, Electric eel is a cholinergic enzyme that is mainly found in neuromuscular junctions and cholinergic chemical synapses and is often used in biochemical research. Acetylcholinesterase, Electric eel can catalyze the decomposition or hydrolysis of acetylcholine and some other choline esters that act as neurotransmitters into acetic acid and choline. The main function of Acetylcholinesterase, Electric eel is to terminate neuronal transmission and signal conduction between synapses to prevent ACh diffusion and activation of nearby receptors .
    Acetylcholinesterase, Electric eel
  • HY-158614
    1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol

    16:0-12-PAHSA-18:1-TG; TG(16:0/12-PAHSA/18:1)

    		 Endogenous Metabolite Others
    1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol (16:0-12-PAHSA-18:1-TG) is a FAHFAs-containing triglyceride that can be synthesized from isotope-labeled FAHFAs, whose decomposition can regulate intracellular FAHFAs levels, and is the major reservoir of FAHFAs in cells and tissues, revealing the activity of a new branch of TG and FAHFAs metabolism.
    1-Palmitoyl-2-12-PAHSA-3-oleoyl-sn-glycerol
  • HY-W145116
    [Ru(phen)3]Cl2

    		Biochemical Assay Reagents
    [Ru(phen)3]Cl2 is an important photocatalyst with photosensitivity and has the activity of promoting reactions in the fields of organic synthesis and photoelectrochemistry. [Ru(phen)3]Cl2 can drive chemical reactions under light conditions and shows good catalytic performance. [Ru(phen)3]Cl2's applications include photocatalytic water decomposition and synthesis of complex organic molecules.
    [Ru(phen)3]Cl2
  • HY-108717B
    Proteinase K (NGS grade)

    Protease K (NGS grade)

    		 Ser/Thr Protease Others
    Proteinase K (Protease K) (NGS grade) (EC 3.4.21.64) is a serine protease with high enzyme activity and broad substrate specificity. Proteinase K can preferentially decompose ester bonds and peptide bonds adjacent to the C-terminus of hydrophobic amino acids, sulfur-containing amino acids, and aromatic amino acids, and is often used to degrade proteins to produce short peptides. This product is NGS grade, no Nickase residue, and nucleic acid residue ≤5pg/mg .
    Proteinase K (NGS grade)
  • HY-W112021
    2,5-DMBQ

    2,5-Dimethoxybenzoquinone

    		 Biochemical Assay Reagents Others
    2,5-DMBQ (2,5-Dimethoxybenzoquinone) serves as an extracellular reductant. 2,5-DMBQ is involved in a crucial redox cycle, namely the extracellular hydroquinone-quinone redox cycle. In this cycle, 2,5-DMBQ is capable of reducing extracellular Fe ³⁺ and generating H2O2. 2,5-DMBQ plays a pivotal role in the biodegradation mechanism of brown rot fungal, assisting the fungi in decomposing and utilizing organic matter .
    2,5-DMBQ
  • HY-W749825
    Pentetic acid-13C5

    Diethylenetriaminepentaacetic acid-13C5; DTPA-13C5

    		 Isotope-Labeled Compounds Fluorescent Dye Others
    Pentetic acid- 13C5 (Diethylenetriaminepentaacetic acid- 13C5) is the 13C-labeled Pentetic acid (HY-B1335). Pentetic acid (Diethylenetriaminepentaacetic acid) is an orally active compound with biodegradability used to construct magnetic adsorbent, which can simultaneously remove heavy metal and dye from complex wastewater. Pentetic acid can form strong metal complexes, which prevents metal ions from catalysing the decomposition of peroxygen chemicals, especially hydrogen peroxide .
    Pentetic acid-13C5
  • HY-B1158
    Imidazolidinyl urea

    		Bacterial Mas-related G-protein-coupled Receptor (MRGPR) Interleukin Related Infection
    Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells .
    Imidazolidinyl urea
  • HY-106784A
    (E)-Ajoene

    		Fungal Apoptosis Neurological Disease
    (E)-Ajoene is a oxygenated ajoene and organosulfur compound, which can be acquired via allicin decomposing. The polysulfides from garlic can be converted by human red blood cells into hydrogen sulfide (H2S) and allyl glutathione. (E)-Ajoene has been proved to show neuroprotective effects against ischemic damage. (E)-Ajoene is orally active to inhibit lipid peroxidation. (E)-Ajoene increases the number of cresyl violet-positive neurons and decreases the number of reactive gliosis in the CA1 region .
    (E)-Ajoene
  • HY-129516
    A-70874

    		Cholecystokinin Receptor Metabolic Disease
    A-70874 is a tyrosine-free tetrapeptide analog of cholecystokinin (30-33) (CCK-4). A-70874 is an agonist that stimulates pancreatic amylase release and a partial agonist that stimulates pancreatic phosphoinositide decomposition. A-70874 has an IC50 of 4.9 nM for the guinea pig pancreatic CCK receptor. Cholecystokinin (CCK) receptors are divided into CCK-A (digestive tract) and CCK-B (brain). A-70874 has an affinity of 1.6 μM for the CCK-B/gastrin receptor .
    A-70874
  • HY-15906
    AMPPD
    1 Publications Verification

    Lumi-Phos Plus; Lumigen PPD; PPD

    		 Phosphatase Others
    AMPPD (Lumi-Phos Plus; Lumigen PPD) is a chemiluminescent substrate for alkaline phosphatase (APase). AMPPD is hydrolyzed by APase to generate an unstable dioxetane intermediate, and the intermediate releases a chemiluminescent signal when it decomposes. The luminescent signal of AMPPD can be detected by highly sensitive equipment, thereby achieving quantitative analysis of the target molecule. AMPPD can be used in ultrasensitive enzyme-linked immunosorbent assays (such as quantitative detection of human tissue kininogen), chemiluminescent detection of proteins and nucleic acids, and other fields .
    AMPPD
  • HY-164117
    BNN6

    		Reactive Oxygen Species (ROS) Apoptosis Cancer
    BNN6 is a thermoresponsive nitric oxide (NO) donor that often works by binding to a carrier. BNN6 decomposes under the heat stimulation generated by photothermal action, releasing high concentrations of NO, which exerts anti-tumor activity by inducing tumor cell apoptosis and inhibiting their repair. BNN6 can be used to synthesize the multifunctional biosensor BNN6-BiTiS3-iRGD, which exerts a synergistic anti-cancer effect with photothermal therapy (PTT) .
    BNN6
  • HY-135078
    2,5-Deoxyfructosazine

    NSC 270912

    		 DNA/RNA Synthesis Others
    2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC50=~1.25 mM).
    2,5-Deoxyfructosazine
  • HY-B1158R
    Imidazolidinyl urea (Standard)

    		Reference Standards Bacterial Mas-related G-protein-coupled Receptor (MRGPR) Interleukin Related Infection
    Imidazolidinyl urea (Standard) is the analytical standard of Imidazolidinyl urea. This product is intended for research and analytical applications. Imidazolidinyl urea is a commonly used antibacterial preservative in cosmetics and pharmaceuticals that releases formaldehyde through decomposition. Imidazolidinyl urea can also be used in the preparation of multifunctional hydrogels for the care of infectious wounds. Imidazolidinyl urea has broad-spectrum antibacterial activity, which mainly inhibits the reproduction of gram-negative bacteria and gram-positive bacteria, and restricts the growth of yeast and mold to a certain extent. Imidazolidinyl urea can induce non-histaminergic allergy by MRGPRX2 activation of mast cells .
    Imidazolidinyl urea (Standard)
  • HY-W251598I
    Sodium bicarbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500

    Sodium hydrogen carbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500

    		 Bacterial Others
    Sodium bicarbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500 is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .
    Sodium bicarbonate, meets analytical specification of Ph. Eur., BP, USP, FCC, E500
  • HY-W251598B
    Sodium bicarbonate, for molecular biology

    Sodium hydrogen carbonate for molecular biology; Soda bicarbonate for molecular biology

    		 Bacterial Others
    Sodium bicarbonate, for molecular biology (Sodium hydrogen carbonate for molecular biolog; Soda bicarbonate for molecular biolog) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .
    Sodium bicarbonate, for molecular biology
  • HY-W241345
    DOTA-bis(tert-butyl)ester

    		Radionuclide-Drug Conjugates (RDCs) Cancer
    DOTA-bis(tert-butyl)ester is a DOTA-based metal chelator that can bind to radionuclides and is used to prepare radionuclide conjugates (RDCs). DOTA-bis(tert-butyl)ester can be conjugated with different salts to form different metal chelators, such as (HY-B1244) hydrochloride to obtain DOTA-MN2. DOTA-MN2 can be reacted with [67]Ga-citrate to obtain radiolabeling. When (67)Ga-DOTA-MN2 is incubated in phosphate buffer solution or mouse plasma for 24 hours, it does not undergo significant decomposition. In the biodistribution experiment of NFSa tumor mice, it has high tumor uptake and rapid plasma clearance, and is a good material for SPECT and PET studies.
    DOTA-bis(tert-butyl)ester
  • HY-D0093
    Ethidium homodimer
    3 Publications Verification

    EthD-1

    		 DNA Stain Others
    Ethidium homodimer (EthD-1) is a high-affinity fluorescent nucleic acid dye commonly used to stain mammals, bacteria, yeast, and fungi. Ethidium homodimer binds to DNA or RNA, enhancing fluorescence more than 30 times. The Ethidium homodimer has a strong positive charge, so it cannot cross cell membranes and stain living cells; But the Ethidium homodimer can cross the disordered region of the dead cell membrane to reach the nucleus and embed the DNA double strand to produce red fluorescence. Therefore, Ethidium homodimer is a relatively sensitive nucleic acid stain that can accurately detect nucleic acids in solution or in decomposing cells. Ethidium homodimer binds DNA, Ex/Em=528/617 nm .
    Ethidium homodimer
  • HY-W251598S
    Bicarbonate-13C sodium

    		Reference Standards Bacterial Others
    Bicarbonate- 13C sodium is the 13C-labeled Sodium bicarbonate (HY-Y0756). Sodium bicarbonate is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .
    Bicarbonate-13C sodium
  • HY-W251598C
    Sodium bicarbonate, for cell culture

    Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture

    		 Bacterial Others
    Sodium bicarbonate, for cell culture (Sodium hydrogen carbonate for cell culture; Soda bicarbonate for cell culture) is an inorganic salt that is neutral to slightly alkaline and easily decomposes when exposed to moisture in the air. Sodium bicarbonate, for cell culture can maintain the pH of the culture medium, thereby affecting the expression of inducible nitric oxide synthase (iNOS) and nitric oxide (NO) production in macrophages and reversing the acidosis of the tumor microenvironment. Sodium bicarbonate is widely used in the fields of food, medicine, cosmetics, etc. Its main uses include buffers, flavoring agents, disinfectants, pharmaceuticals, and proton gradient regulators. Sodium bicarbonate is also commonly used as an antacid to inhibit gastrointestinal diseases, neutralize gastric acid, and reduce gastric discomfort .
    Sodium bicarbonate, for cell culture

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