Search Result
Results for "
ganoderic acid
" in MedChemExpress (MCE) Product Catalog:
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
-
- HY-N6036
-
|
|
Others
|
Cancer
|
|
Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress .
|
-
-
- HY-N2006
-
|
|
EBV
HIV Protease
|
Infection
Inflammation/Immunology
|
|
Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) .
|
-
-
- HY-N11638
-
|
|
Apoptosis
|
Cancer
|
|
Ganoderic acid R is a potent anticancer agent. Ganoderic acid R inhibits the growth by inducing apoptosis on tumor cell line. Ganoderic acid R possesses significant cytotoxicity on a multidrug resistance (MDR) tumor cell line (KB-A-1/Dox) and a sensitive tumor cell line (KB-A-1) .
|
-
-
- HY-N6036R
-
|
|
Others
|
Cancer
|
|
Ganoderic acid F (Standard) is the analytical standard of Ganoderic acid F. This product is intended for research and analytical applications. Ganoderic acid F is a ganoderic acid. Ganoderic acid F exhibits antitumor and antimetastatic activities through inhibition of angiogenesis and alteration of proteins involving cell proliferation and/or cell death, carcinogenesis, oxidative stress, calcium signaling, and endoplasmic reticulum stress .
|
-
-
- HY-N11636
-
|
|
Apoptosis
|
Cancer
|
|
Ganoderic acid S is a positional isomer of ganoderic acids, that can be isolated from the fermented mycelia of Ganoderma lucidum. Ganoderic acid S can induce apoptosis in HeLa cells through the mitochondria pathway .
|
-
-
- HY-113898
-
-
-
- HY-N2006R
-
|
|
EBV
HIV Protease
|
Infection
Inflammation/Immunology
|
|
Ganoderic acid B (Standard) is the analytical standard of Ganoderic acid B. This product is intended for research and analytical applications. Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM) .
|
-
-
- HY-N11648
-
|
|
Apoptosis
Caspase
|
Inflammation/Immunology
Cancer
|
|
Ganoderic acid T1 is a deacetylated derivative of Ganoderic acid T. Ganoderic acid T1 attenuates antioxidant defense system and induces apoptosis of cancer cells. Ganoderic acid T1 decreases mitochondrial membrane potential and activates caspase-9 and caspase-3, to trigger apoptosis. Ganoderic acid T1 also increases the generation of intracellular ROS to produce pro-oxidant activities and cytotoxicity .
|
-
-
- HY-N1447R
-
|
|
Apoptosis
Autophagy
Endogenous Metabolite
|
Cancer
|
|
Ganoderic acid A (Standard) is the analytical standard of Ganoderic acid A. This product is intended for research and analytical applications. Ganoderic acid A can inhibit of the JAK-STAT3 signaling pathway, also inhibit proliferation, viability, ROS.
|
-
-
- HY-N1511R
-
|
|
Sirtuin
Apoptosis
|
Cancer
|
|
Ganoderic acid D (Standard) is the analytical standard of Ganoderic acid D. This product is intended for research and analytical applications. Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
|
-
-
- HY-N9312
-
|
|
Others
|
Inflammation/Immunology
|
|
Ganoderic acid J is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid J possesses anti-inflammatory anti-inflammatory activity .
|
-
-
- HY-N9350
-
|
|
Others
|
Cancer
|
|
Ganoderic acid ε is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid ε exhibits an ED50 of 12.2 μg/mL in Meth-A tumor cells
|
-
-
- HY-N1511
-
|
|
Sirtuin
Apoptosis
|
Cancer
|
|
Ganoderic acid D, a highly oxygenated tetracyclic triterpenoid, is the major active component of Ganoderma lucidum. Ganoderic acid D upregulates the protein expression of SIRT3 and induces the deacetylated cyclophilin D (CypD) by SIRT3. Ganoderic acid D inhibits the energy reprogramming of colon cancer cells including glucose uptake, lactate production, pyruvate and acetyl-coenzyme production in colon cancer cells . Ganoderic acid D induces HeLa human cervical carcinoma apoptosis .
|
-
-
- HY-129149
-
|
|
HMG-CoA Reductase (HMGCR)
|
Metabolic Disease
|
|
Ganoderic acid SZ is a natural product with 3-hydroxy-3-methylglutaryl-CoA reductase inhibitory activity. Ganoderic acid SZ shows stronger activity than the positive control atorvastatin in inhibiting HMG-CoA reductase. Ganoderic acid SZ exhibits significant inhibition of yeast-derived α-glucosidase with IC50 values achieved at very low concentrations. Ganoderic acid SZ also exhibits cytotoxicity against K562 cells with IC?? values in the range of 10-20 μM .
|
-
-
- HY-N13411
-
-
-
- HY-N11639
-
|
|
Aldose Reductase
|
Metabolic Disease
|
|
Ganoderic acid Df is a lanostane-type triterpenoid, that can be isolated from the fruiting body of Ganoderma lucidum. Ganoderic acid Df potently inhibits aldose reductase, with an IC50 of 22.8 ± 0.6 μM .
|
-
-
- HY-N1517R
-
|
|
Aldose Reductase
|
Cancer
|
|
Ganoderic acid C2 (Standard) is the analytical standard of Ganoderic acid C2. This product is intended for research and analytical applications. Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM .
|
-
-
- HY-N2997
-
|
|
Others
|
Cancer
|
|
Ganoderic acid LM2 is a natural terpenoid isolated from the Fungus Ganoderma lucidum. Ganoderic acid LM2 possesses potential anti-tumor activity .
|
-
-
- HY-N3500
-
-
-
- HY-N1512
-
|
|
Others
|
Others
|
|
Ganoderic acid E is a triterpenoid found in Ganoderma lucidum .
|
-
-
- HY-N2999
-
|
|
Others
|
Others
|
|
Ganoderic acid I is a triterpenoid found in ganoderma lucidum .
|
-
-
- HY-N1517
-
|
|
Aldose Reductase
|
Cancer
|
|
Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses the potential anti-tumor bioactivity, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM .
|
-
-
- HY-N11645
-
|
GA-Mf
|
Apoptosis
|
Cancer
|
|
Ganoderic acid Mf is an antitumor triterpenoid. Ganoderic acid Mf causes cell cycle arrest in the G1 phase. Ganoderic acid Mf shows high selectivity between normal and cancer cells and induces cell apoptosis via mitochondria mediated pathway .
|
-
-
- HY-125713
-
|
|
Glycosidase
Enterovirus
|
Infection
|
|
Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating .
|
-
-
- HY-120140
-
-
-
- HY-N1513
-
|
|
AP-1
NF-κB
|
Cancer
|
|
Ganoderic acid H is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderic acid H suppresses growth and invasive behavior of breast cancer cells through the inhibition of transcription factors AP-1 and NF-kappaB signaling .
|
-
-
- HY-N11643
-
|
GA-Mk
|
Apoptosis
Reactive Oxygen Species
MMP
Caspase
|
Cancer
|
|
Ganoderic acid Mk (GA-Mk) is a triterpenoid acid, that can be isolated from the mycelia of Ganoderma lucidum. Ganoderic acid Mk is efficiently anti-proliferative and can induce apoptosis of HeLa cells by mitochondria-mediated pathway. Ganoderic acid Mk can be used for cervical cancer research .
|
-
-
- HY-N11591
-
|
|
Others
|
Others
|
|
Ganoderic acid T is a natural product that can be found in ganoderma lucidum .
|
-
-
- HY-129153
-
|
|
Others
|
Others
|
|
Ganoderic acid ζ is a triterpene that can be isolated from the spores of Ganoderma lucidum .
|
-
-
- HY-N2458
-
|
|
Others
|
Infection
|
|
Ganoderic acid G is a triterpene isolated from the surface part of gills of Ganoderma lucidum .
|
-
-
- HY-123100
-
|
|
Others
|
Others
|
|
Ganoderic acid N is a natural terpenoid isolated from the Fungus Ganoderma lucidum .
|
-
-
- HY-N2461
-
-
-
- HY-N1447
-
-
-
- HY-129148
-
|
GAAM1
|
Others
|
Cancer
|
|
Ganoderic acid AM1 (GAAM1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid AM1 shows cytotoxicity with an IC50 value of 19.8 µM for HeLa cells .
|
-
-
- HY-N3923
-
|
|
Others
|
Others
|
|
Ganoderic acid S1 (compound 4) is a natural product that can be found in ganoderma lucidum .
|
-
-
- HY-N8039
-
|
Ganodermic acid T-Q
|
Microtubule/Tubulin
|
Cancer
|
|
Ganoderic acid T-Q (Ganodermic acid T-Q) (compound 1) is a natural product that can be found in ganoderma lucidum. Ganoderic acid T-Q stimulates tubulin polymerization .
|
-
-
- HY-129152
-
|
|
Influenza Virus
|
Infection
|
|
Ganoderic acid T-N, a triterpenoid, is a H5N1 and H1N1 influenza neuraminidase (NA) inhibitor with IC50s of 2.7 μM and 42 μM, respectively. Ganoderic acid T-Q shows cytotoxicity against MCF7 cells (CC50=24.4 μM) .
|
-
-
- HY-N13717
-
|
|
Others
|
Others
|
|
Ganoderic acid GS-3 is a lanostane-type triterpenoid compound that can be isolated from Ganoderma sinense .
|
-
-
- HY-N10934
-
|
|
HIV Protease
|
Infection
|
|
Ganoderic acid GS-1, a highly oxygenated lanostane-type triterpenoid, has anti-HIV-1 protease activities with an IC50 of 58 μM .
|
-
-
- HY-129151
-
|
|
Others
|
Inflammation/Immunology
|
|
Ganoderic acid C1, a natural compound that could be isolated from G. lucidum, suppresses TNF-α production by murine macrophages (RAW 264.7 cells) .
|
-
-
- HY-129150
-
|
|
Influenza Virus
|
Infection
|
|
Ganoderic acid TR is a broad-spectrum inhibitor against influenza neuraminidases (NAs), particularly H5N1 and H1N1 neuraminidases. The IC50 values of 10.9 and 4.6 μM, respectively .
|
-
-
- HY-N1517A
-
|
|
Aldose Reductase
|
Cancer
|
|
(Rac)-Ganoderic acid C2 is the racemate of Ganoderic acid C2 (HY-N1517). Ganoderic acid C2 is a bioactive triterpenoid in Ganoderma lucidum. Ganoderic acid C2 possesses anti-tumor, antihistamine, anti-aging and cytotoxic effects. Ganoderic acid C2 exhibits high inhibitory activity against the rat lens aldose reductase (RLAR) with an IC50 of 3.8 µM[ .
|
-
-
- HY-N8588
-
|
|
Others
|
Others
|
|
Methyl ganoderate C6 is a ganoderic acid. Methyl ganoderate C6 can be used for the research of various biochemical .
|
-
-
- HY-N11640
-
|
|
Others
|
Neurological Disease
|
|
Methyl Ganoderic acid B is a triterpenoid, that can be isolated from Ganoderma lucidum. Methyl Ganoderic acid B has nerve growth factor-like neuronal survival-promoting effects .
|
-
-
- HY-N10930
-
|
|
Bacterial
|
Infection
|
|
7-Oxo-ganoderic acid Z, a terpenoid, is a nature product that could be isolated from Resina Commiphora. 7-Oxo-ganoderic acid Z has Anti-Mycobacterium tuberculosis activity .
|
-
-
- HY-N3501
-
-
-
- HY-107259
-
|
23S-Hydroxy-3,7,11,15-tetraoxo-lanost-8,24E-diene-26-oic
|
Others
|
Others
|
|
23S-Hydroxyl-11,15-dioxo-ganoderic acid DM is a compound isolated from the fruit bodies of Ganoderma lucidum .
|
-
-
- HY-N11646
-
|
|
Bacterial
|
Infection
|
|
Ganorbiformin B is a lanostane triterpenoid. Ganorbiformin B shares the same lanostane skeleton with known ganoderic acids. The C-3 epimer of ganoderic acid T exhibits potent antimycobacterial activity against Mycobacterium tuberculosis H37Ra .
|
-
-
- HY-162450
-
|
|
PROTACs
MDM-2/p53
Apoptosis
|
Cancer
|
Antitumor agent-150 (V10), an anti-breast cancer agent, is a PROTAC-based MDM2 protein degrader (Red: Ganoderic acid A; Black: 4O-PEG linker; Blue: VHL ligand) .
|
-
-
- HY-N11644
-
|
|
Others
|
Cancer
|
|
Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid, also known as ganoderic acid 24. Lanosta-7,9(11),24-trien-3α-hydroxy-26-oic acid shows high cytotoxicity against cancer cells, such as human lung cancer cells CH27, melanoma cells M21, and oral cancer cells HSC-3 .
|
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
Your information is safe with us. * Required Fields.
Inquiry Information
- Product Name:
- Cat. No.:
- Quantity:
- MCE Japan Authorized Agent:
