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halogenated

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (1) Antibiotic (2) Apoptosis (3) Bacterial (2) Biochemical Assay Reagents (4) Calcium Channel (1) Drug Derivative (2) Drug Intermediate (1) Drug Isomer (1) Fluorescent Dye (1) Glucocorticoid Receptor (3) Glutathione Peroxidase (1) HSV (1) Isotope-Labeled Compounds (1) Microtubule/Tubulin (1) Opioid Receptor (1) Oxidative Phosphorylation (2) p38 MAPK (2) Parasite (7) Potassium Channel (2) Raf (2)
By Research Areas:	Cancer (6) Infection (9) Inflammation/Immunology (3) Neurological Disease (4)

By Targets:

5-HT Receptor (1)

Antibiotic (2)

Apoptosis (3)

Bacterial (2)

Biochemical Assay Reagents (4)

Calcium Channel (1)

Drug Derivative (2)

Drug Intermediate (1)

Drug Isomer (1)

Fluorescent Dye (1)

Glucocorticoid Receptor (3)

Glutathione Peroxidase (1)

HSV (1)

Isotope-Labeled Compounds (1)

Microtubule/Tubulin (1)

Opioid Receptor (1)

Oxidative Phosphorylation (2)

p38 MAPK (2)

Parasite (7)

Potassium Channel (2)

Raf (2)

By Research Areas:

Cancer (6)

Infection (9)

Inflammation/Immunology (3)

Neurological Disease (4)

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-17596A

Closantel sodium Maximum Cited Publications 6 Publications Verification	Parasite	Infection
Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC₅₀ of 1.6 μM and a K_i of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .

HY-17596

Closantel Maximum Cited Publications 6 Publications Verification	Parasite	Infection
Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC₅₀ of 1.6 μM and a K_i of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .

HY-59299

3-Bromothiophene 3-Bromothiophene	Biochemical Assay Reagents	Others
3-Bromothiophene is a bromine atom-substituted 3-halogenated thiophene with electrochemical stability, small porosity, and high π-π* lowest transition energy. 3-Bromothiophene is often used as a conductive polymer monomer .

HY-13742

Ropidoxuridine IPdR	HSV	Cancer
Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors.

HY-17598

Rafoxanide 4 Publications Verification	Oxidative Phosphorylation Parasite p38 MAPK Raf Apoptosis	Infection Cancer
Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research .

HY-133647

Dibromoacetaldehyde	Others	Others
Dibromoacetaldehyde, a halogenated product, is a byproduct in drinking water and has genotoxicity .

HY-I0834

(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran	Microtubule/Tubulin	Cancer
(S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran (compound 2d), a halogenated Phenstatin analog, is a microtubule destabilizing agent. (S)-3-(4-(2-Chloro-5-iodobenzyl)phenoxy)tetrahydrofuran shows anticancer activities .

HY-17596AR

Closantel (sodium) (Standard)	Parasite	Infection
Closantel (sodium) (Standard) is the analytical standard of Closantel (sodium). This product is intended for research and analytical applications. Closantel sodium is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel sodium is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC₅₀ of 1.6 μM and a Ki of 468 nM. Closantel sodium inhibits the O. volvulus L3 to L4 molt of developing .

HY-17596R

Closantel (Standard)	Parasite	Infection
Closantel (Standard) is the analytical standard of Closantel. This product is intended for research and analytical applications. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing .

HY-168350

Chlorphine	Opioid Receptor	Neurological Disease
Chlorphine is a neuroactive halogenated opioid analog .

HY-136824

Napyradiomycin A1	Bacterial Antibiotic	Infection Cancer
Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains .

HY-133629

1,1,1,3-Tetrachloroacetone	Drug Intermediate	Others
1,1,1,3-Tetrachloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133625

1,1-Dibromo-3-chloroacetone	Biochemical Assay Reagents	Others
1,1-Dibromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-131556

4-Iodoamphetamine hydrochloride p-Iodoamphetamine hydrochloride	5-HT Receptor	Neurological Disease
4-Iodoamphetamine (p-Iodoamphetamine) hydrochloride is a halogenated amphetamine featuring an iodine atom at the para position of the phenyl group. 4-Iodoamphetamine hydrochloride selectively induces serotonin release and inhibits reuptake by rat brain synaptosomes.

HY-133628

1,1,3-Tribromo-3-chloroacetone	Biochemical Assay Reagents	Others
1,1,3-Tribromo-3-chloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133626

1,1-Dibromo-3,3-dichloroacetone	Drug Derivative	Others
1,1-Dibromo-3,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-133627

1,3-Dibromo-1,3-dichloroacetone	Drug Derivative	Others
1,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant .

HY-125922

(22R)-Budesonide (22R)-BUD	Glucocorticoid Receptor Drug Isomer	Inflammation/Immunology
(22R)-Budesonide ((22R)-BUD) is the (22R)-enantiomer of Budesonide (HY-13580). (22R)-Budesonide is a non-halogenated glucocorticoid with high local anti-inflammatory activity .

HY-106673

Hydrocortisone buteprate 1 Publications Verification Hydrocortisone probutate; HBP	Glucocorticoid Receptor	Inflammation/Immunology
Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation .

HY-A0135

Enflurane	Potassium Channel	Neurological Disease
Enflurane, a volatile anaesthetic, is a potent inhibitor of high conductance Ca ²⁺-activated K+ channels of Chara australis. Enflurane is an internal standard in monitoring halogenated volatile anaesthetics by headspace gas chromatography-mass spectrometry .

HY-N6694

4-Bromo A23187	Calcium Channel Bacterial Apoptosis Antibiotic	Infection Cancer
4-Bromo A23187 is a halogenated analog of the highly selective calcium ionophore A-23187. 4-Bromo A23187, a calcium modulator, induces apoptosis in different cells, including HL-60 cells .

HY-D0169A

Phenol Red sodium salt 1 Publications Verification Phenolsulfonephthalein sodium salt	Fluorescent Dye Glutathione Peroxidase	Others
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye. Phenol Red sodium salt is also an antagonist of rat P2X1R. Phenol Red sodium salt enhances the halogenating activity of myeloperoxidase. Phenol Red sodium salt shows a distinct color change from pink to yellow in a positive pH reaction .

HY-17596S

Closantel-13C6	Isotope-Labeled Compounds Parasite	Infection
Closantel- ¹³C₆ is the ¹³C₆ labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

HY-106673R

Hydrocortisone buteprate (Standard)	Glucocorticoid Receptor	Inflammation/Immunology
Hydrocortisone buteprate (Standard) is the analytical standard of Hydrocortisone buteprate. This product is intended for research and analytical applications. Hydrocortisone buteprate (Hydrocortisone probutate) is a medium potent, non-halogenated double-ester of hydrocortisone with a favorable benefit/risk ratio for the treatment of inflammatory skin disorders. Hydrocortisone buteprate (Hydrocortisone probutate) is available as a 0.1% cream or ointment formulation .

HY-W011972

Bromocholine bromide	Biochemical Assay Reagents	Others
2-Bromo-N,N,N-trimethylethanaminium bromide is a quaternary ammonium salt consisting of a positively charged 2-bromo-N,N,N-trimethylethylamine cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a halogenating agent, for example in the bromination of olefins.

HY-17598R

Rafoxanide (Standard)	Oxidative Phosphorylation Parasite p38 MAPK Raf Apoptosis	Infection Cancer
Rafoxanide (Standard) is the analytical standard of Rafoxanide. This product is intended for research and analytical applications. Rafoxanide is a poent, orally active halogenated salicylaniline agent with antiparasitic activity. Rafoxanide interferes with energy metabolism in trematodes by uncoupling oxidative phosphorylation. Rafoxanide is also found to be a potent inhibitor of the BRAF V600E mutant protein, which is important in colorectal cancer. Rafoxanide can be used for the control of infestation with Hemonchus species or Fasciola species in sheep and cattle as well as Oestrus ovis in sheep. Rafoxanide can also be used for cancer research .

HY-B0718

Methoxyflurane DA-759	Potassium Channel	Neurological Disease
Methoxyflurane disrupts neuronal transmission by interfering with the release and re-uptake of neurotransmitters at post-synaptic terminals, or altering ionic conductance following receptor activation[1]. Methoxyflurane is an analgesic agent that provides rapid short-term analgesia. Methoxyflurane may shows a effective non-opioid treatment option for trauma pain .

Cat. No.	Product Name	Type

HY-D0169A

Phenol Red sodium salt 1 Publications Verification Phenolsulfonephthalein sodium salt	Dyes
Phenol red (Phenolsulfonephthalein) sodium salt is a pH indicator dye. Phenol Red sodium salt is also an antagonist of rat P2X1R. Phenol Red sodium salt enhances the halogenating activity of myeloperoxidase. Phenol Red sodium salt shows a distinct color change from pink to yellow in a positive pH reaction .

Cat. No.	Product Name	Type

HY-59299

3-Bromothiophene 3-Bromothiophene	Biochemical Assay Reagents
3-Bromothiophene is a bromine atom-substituted 3-halogenated thiophene with electrochemical stability, small porosity, and high π-π* lowest transition energy. 3-Bromothiophene is often used as a conductive polymer monomer .

HY-W011972

Bromocholine bromide	Biochemical Assay Reagents
2-Bromo-N,N,N-trimethylethanaminium bromide is a quaternary ammonium salt consisting of a positively charged 2-bromo-N,N,N-trimethylethylamine cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a halogenating agent, for example in the bromination of olefins.

Bromocholine bromide

Biochemical Assay Reagents

2-Bromo-N,N,N-trimethylethanaminium bromide is a quaternary ammonium salt consisting of a positively charged 2-bromo-N,N,N-trimethylethylamine cation and a negatively charged bromide anion. This compound is commonly used as a phase transfer catalyst in organic chemical reactions, facilitating the transfer of reactants between immiscible phases. It can also be used as a halogenating agent, for example in the bromination of olefins.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-136824

Napyradiomycin A1	Infection Quinones Microorganisms Classification of Application Fields Source classification Naphthalene Quinones Disease Research Fields Cancer	Bacterial Antibiotic
Napyradiomycin A1 is one enantioselective compound of napyradiomycins. napyradiomycins are an intriguing family of halogenated natural products with activity against several tumor cell lines as well as some bacterial strains .

Cat. No.	Product Name	Chemical Structure

HY-17596S

Closantel-13C6
Closantel- ¹³C₆ is the ¹³C₆ labeled Closantel. Closantel is a halogenated salicylanilide with a potent anti-parasitic activity. Closantel is a potent and highly specific Onchocerca volvulus chitinase (OvCHT1) inhibitor with an IC50 of 1.6 μM and a Ki of 468 nM. Closantel inhibits the O. volvulus L3 to L4 molt of developing.

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halogenated

Inhibitors & Agonists

Fluorescent Dye

Biochemical Assay Reagents

NaturalProducts

Isotope-Labeled Compounds

Natural
Products