jack bean

By Targets:	Antibiotic (1) Apoptosis (1) Bacterial (4) Biochemical Assay Reagents (1) Parasite (1) Reactive Oxygen Species (1) Urease (2)
By Research Areas:	Cancer (2) Infection (4) Inflammation/Immunology (1) Metabolic Disease (3)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2767

Urease, Jack bean	Bacterial	Others
Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids.

HY-P2149

Concanavalin A 4 Publications Verification	Antibiotic Apoptosis	Infection Inflammation/Immunology Cancer
Concanavalin A is a Ca ²⁺/Mn ²⁺-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury .

HY-W176199

DPPD-Q	Reactive Oxygen Species	Metabolic Disease
DPPD-Q is an oxidized derivative of the antioxidant and substituted p-phenylenediamine DPPD, which is found in tire wear particles and crumb rubber, particulate matter 2.5 (PM2.5), and wastewater influent and effluent. DPPD-Q inhibits jack bean urease by 91.4% at 5 µM .

HY-N1470

Plantagoside	Others	Metabolic Disease
Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC₅₀ of 5 μM .

HY-P2149A

Concanavalin A (agarose)	Biochemical Assay Reagents	Others
Concanavalin A (agarose) consists of Concanavalin A (HY-P2149) coupled to agarose. Concanavalin A is a tetrameric metalloprotein lectin isolated from Canavalia ensiformis (jack bean). Concanavalin A (agarose) is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. Concanavalin A (agarose) has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles .

HY-115939

Urease-IN-2	Bacterial Urease	Infection
Urease-IN-2 (compound 8g) is a non-competitive urease inhibitor with an IC₅₀ of 0.94 μM and a K_i of 1.6 μM. Urease-IN-2 inhibits the Jack bean urease (JBU) in a non-competitive manner .

HY-149775

Urease-IN-10	Bacterial Urease	Infection
Urease-IN-10 (Conjugate 4) is a competitive Urease inhibitor, with an IC₅₀ of 3.59±0.07 μM and a K_i of 7.45 μM. Urease-IN-10 is a conjugate consisting of Diclofenac (HY-15036) and Sulfanilamide (HY-B0242). Diclofenac-sulfanilamide inhibits the Jack bean urease(JBU) in a competitive manner .

HY-N1470R

Plantagoside (Standard)	Others	Metabolic Disease
Plantagoside (Standard) is the analytical standard of Plantagoside. This product is intended for research and analytical applications. Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC50 of 5 μM .

HY-N9746

(R)-4-Methoxydalbergione	Parasite	Infection
(R)-4-Methoxydalbergione is a urease inhibitor with IC₅₀s of 59.72 and 67.33 μM for Bacillus pasteurii urease and Jack bean urease. (R)-4-Methoxydalbergione also has antiplasmodial activity. (R)-4-Methoxydalbergione can be isolated from Ranunculus repens .

HY-161860

Antibacterial agent 233	Bacterial	Cancer
Antibacterial agent 233 (Compound 7c) exhibits inhibitory efficacy against Helicobacter pylori with MIC of 0.4-1.6 μg/mL. Antibacterial agent 233 inhibits jack bean urease (IC₅₀ is 0.27 μg/mL), changes the permeability of H. pylori cell membrane, causes the leakage of cellular contents. Antibacterial agent 233 exhibits metabolic stability in whole blood and artificial gastric fluid. Antibacterial agent 233 exhibits antitumor efficacy against U2OS in mice .

Cat. No.	Product Name	Type

HY-P2149

Concanavalin A 4 Publications Verification	Native Proteins
Concanavalin A is a Ca ²⁺/Mn ²⁺-dependent and mannose/glucose-binding plant lectin that can be found in jack bean. Concanavalin A can induce programmed cell death. Concanavalin A can be used to induce acute hepatic injury .

HY-P2149A

Concanavalin A (agarose)	Native Proteins
Concanavalin A (agarose) consists of Concanavalin A (HY-P2149) coupled to agarose. Concanavalin A is a tetrameric metalloprotein lectin isolated from Canavalia ensiformis (jack bean). Concanavalin A (agarose) is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. Concanavalin A (agarose) has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles .

Concanavalin A (agarose)

Native Proteins

Concanavalin A (agarose) consists of Concanavalin A (HY-P2149) coupled to agarose. Concanavalin A is a tetrameric metalloprotein lectin isolated from Canavalia ensiformis (jack bean). Concanavalin A (agarose) is used for the purification of glycoproteins, polysaccharides and glycolipids as it binds molecules containing α-D-mannopyranosyl, α-D-glucopyranosyl and sterically related residues. Concanavalin A (agarose) has also be used in other application areas including purification of enzyme-antibody conjugates, purification of IgM and separation of membrane vesicles .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1470

Plantagoside	Plantaginaceae Structural Classification Flavonoids Classification of Application Fields Flavonones Source classification Phenols Polyphenols Metabolic Disease Plantago asiatica L. Plants Disease Research Fields	Others
Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC₅₀ of 5 μM .

HY-N1470R

Plantagoside (Standard)	Plantaginaceae Structural Classification Flavonoids Flavonones Source classification Phenols Polyphenols Plantago asiatica L. Plants	Others
Plantagoside (Standard) is the analytical standard of Plantagoside. This product is intended for research and analytical applications. Plantagoside, isolated from the seeds of Plantago asiatica, is a specific and non-competitive inhibitor for jack bean α-mannosidase, with an IC50 of 5 μM .

HY-N9746

(R)-4-Methoxydalbergione	Structural Classification Natural Products Ranunculus repens L. Source classification Ranunculaceae Plants	Parasite
(R)-4-Methoxydalbergione is a urease inhibitor with IC₅₀s of 59.72 and 67.33 μM for Bacillus pasteurii urease and Jack bean urease. (R)-4-Methoxydalbergione also has antiplasmodial activity. (R)-4-Methoxydalbergione can be isolated from Ranunculus repens .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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