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multiprotein

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By Targets:	Histone Demethylase (1) Wnt (1)
By Research Areas:	Cancer (4) Inflammation/Immunology (1)

3

Inhibitors & Agonists

3

Peptides

1

Recombinant Proteins

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

JW67 1 Publications Verification	Wnt	Cancer
JW67 inhibits the canonical Wnt signaling with an IC₅₀ of 1.17μM . JW67 affects the multiprotein complex consisting of β-catenin/GSK-3β/AXIN/APC/CK1 that rapidly reduces active β-catenin with a subsequent downregulation of Wnt target genes. JW67 also inhibits colorectal cancer cell growth .

KMU-11342	Others	Inflammation/Immunology
KMU-11342 is a potent inhibitor of multi-protein kinase. KMU-11342 plays an important inhibitor of rheumatoid arthritis (RA) research .

H3K27(Me2) (15-34)	Histone Demethylase	Cancer
H3K27(Me2) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me) .

Cat. No.	Product Name	Target	Research Area

H3K27(Me3) (15-34)	Peptides	Cancer
H3K27(Me3) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me) .

H3K27(Me) (15-34)	Peptides	Cancer
H3K27(Me) (15-34), a histone peptide, is a repressive chromatin markderived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me) .

H3K27(Me2) (15-34)	Histone Demethylase	Cancer
H3K27(Me2) (15-34), a histone peptide, is a repressive chromatin mark derived from human histone. Polycomb Repressive Complex 2 (PRC2) is a multiprotein complex that catalyzes the methylation of H3K27(Me) .

Cat. No.	Compare	Product Name	Species	Source

	*EDF1/MBF1 Protein, Human (His)* rHuEndothelial differentiation-related factor 1/EDF1, His; Endothelial Differentiation-Related Factor 1; EDF-1; multiprotein-Bridging Factor 1; MBF1; EDF1	Human	E. coli
	The EDF1/MBF1 protein is a transcriptional coactivator that stimulates NR5A1, NR1H3/LXRA, and PPARG transcriptional activity. It enhances ATF1, ATF2, CREB1 and NR5A1 DNA binding. EDF1/MBF1 Protein, Human (His) is the recombinant human-derived EDF1/MBF1 protein, expressed by E. coli , with C-6*His labeled tag. The total length of EDF1/MBF1 Protein, Human (His) is 147 a.a., with molecular weight of 16 & 40 kDa, respectively.

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