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Results for "

nausea and vomiting

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (37) Autophagy (2) Calcium Channel (2) Cytochrome P450 (2) Dopamine Receptor (15) Drug Metabolite (1) Enterovirus (2) Flavivirus (1) Fungal (1) HCV Protease (1) Histamine Receptor (9) Influenza Virus (2) Isotope-Labeled Compounds (11) mAChR (1) NADPH Oxidase (1) Neurokinin Receptor (8)
By Research Areas:	Cancer (24) Cardiovascular Disease (5) Endocrinology (12) Infection (3) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (42)

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Natural
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Isotope-Labeled Compounds

Targets Recommended: Fat Mass and Obesity-associated Protein (FTO)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-12751A

Trimethobenzamide hydrochloride Ro 2-9578	Dopamine Receptor Influenza Virus	Others
Trimethobenzamide hydrochloride is a blocker of the D₂ receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

HY-B0071

Granisetron BRL 43694	5-HT Receptor	Neurological Disease
Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-167639

(S)-Ramosetron (S)-YM060 free base	5-HT Receptor	Metabolic Disease
(S)-Ramosetron ((S)-YM060 (free base)) is an orally active antagonist of the 5-hydroxytryptamine 5-HT₃ receptor. (S)-Ramosetron is promising for research of diseases related to nausea and vomiting, irritable bowel syndrome (IBS) .

HY-172514

(1R,2S,3R)-Aprepitant	Neurokinin Receptor	Cancer
(1R,2S,3R)-Aprepitant (Compound ent-4) is a competitive human neurokinin-1 (NK-1) receptor antagonist. (1R,2S,3R)-Aprepitant is promising for research of cancers and postoperative nausea and vomiting .

HY-A0125AS

Alizapride-13C,d3 hydrochloride	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease Cancer
Alizapride- ¹³C,d₃ (hydrochloride) is deuterium labeled Alizapride (hydrochloride). Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.

HY-A0018

Palonosetron	5-HT Receptor	Cardiovascular Disease Cancer
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV).

HY-14405

Casopitant GW679769	Neurokinin Receptor Cytochrome P450	Neurological Disease
Casopitant (GW679769) is a potent, selective, brain-penetrant and orally active neurokinin 1 (NK₁) receptor antagonist. Casopitant antagonizes the emetic effects of Substance P (HY-P0201). Casopitant is also a substrate and weak to moderate inhibitor of CYP3A4. Casopitant is indicated for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) .

HY-12751

Trimethobenzamide Ro 2-9578 free base	Dopamine Receptor	Neurological Disease
Trimethobenzamide (Ro 2-9578 free base) is a blocker of the D₂ receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting .

HY-101729

Anti-Heart Failure Agent 1	Others	Cardiovascular Disease
Anti-Heart Failure Agent 1 an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.

HY-12751S

Trimethobenzamide-d6 Ro 2-9578 free base D6	Isotope-Labeled Compounds Dopamine Receptor	Neurological Disease
Trimethobenzamide-d₆ is deuterium labeled Trimethobenzamide. Trimethobenzamide is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

HY-B0750

Dolasetron MDL-73147	5-HT Receptor	Others
Dolasetron(MDL-73147) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

HY-B0071A

Granisetron Hydrochloride BRL 43694A	5-HT Receptor	Neurological Disease Cancer
Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-14405A

Casopitant mesylate GW679769B	Neurokinin Receptor Cytochrome P450	Neurological Disease Cancer
Casopitant mesylate (GW679769B) is a potent, selective, brain permeable and orally active neurokinin 1 (NK1) receptor antagonist. Casopitant mesylate is a second in the class of antiemetics that acts to antagonise the emetogenic effect of Substance P (HY-P0201). Casopitant mesylate is also a substrate and a weak-to-moderate inhibitor of CYP3A4. Casopitant mesylate can be used for chemotherapy-induced nausea and vomiting (CINV) and postoperative nausea and vomiting (PONV) .

HY-B0019

Azasetron (Rac)-SENS-401 free base	5-HT Receptor	Neurological Disease
Azasetron ((Rac)-SENS-401 free base) is an antiemetic drug with 5-HT3 receptor antagonist activity. Azasetron is often used as a preventive measure for postoperative nausea and vomiting or chemotherapy-induced nausea and vomiting. Azasetron does not impair neutrophil chemotaxis or phagocytosis and does not scavenge O(-)(2) or H(2)O(2) generated by cell-free systems .

HY-B1164A

Bromopride hydrochloride	Dopamine Receptor	Neurological Disease
Bromopride hydrochloride is a prokinetic drug with antiemetic activity. Bromopride hydrochloride is used to suppress nausea and vomiting, especially in the management of upper gastrointestinal dysmotility. Bromopride hydrochloride, as a dopamine D2 receptor antagonist, is clinically used to suppress functional dyspepsia, gastric retention and vomiting caused by various reasons .

HY-B1397C

Cyclizine hydrochloride	Histamine Receptor	Neurological Disease
Cyclizine hydrochloride, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine hydrochloride can be used for the research of nausea, vomiting, and dizziness .

HY-B0750B

Dolasetron Mesylate hydrate MDL-73147EF hydrate	5-HT Receptor	Others
Dolasetron Mesylate hydrate (MDL-73147EF hydrate) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

HY-B1397A

Cyclizine dihydrochloride	Histamine Receptor	Neurological Disease
Cyclizine dihydrochloride, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine dihydrochloride can be used for the research of nausea, vomiting, and dizziness .

HY-B0750A

Dolasetron Mesylate MDL-73147EF	5-HT Receptor	Cancer
Dolasetron Mesylate (MDL-73147EF) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy.

HY-B1397

Cyclizine	Histamine Receptor	Neurological Disease
Cyclizine, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine can be used for the research of nausea, vomiting, and dizziness .

HY-12751AR

Trimethobenzamide (hydrochloride) (Standard)	Dopamine Receptor Influenza Virus	Others
Trimethobenzamide (hydrochloride) (Standard) is the analytical standard of Trimethobenzamide (hydrochloride). This product is intended for research and analytical applications. Trimethobenzamide hydrochloride is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

HY-B1397B

Cyclizine lactate	Histamine Receptor	Neurological Disease
Cyclizine lactate, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine lactate can be used for the research of nausea, vomiting, and dizziness .

HY-B0002

Ondansetron hydrochloride 5+ Cited Publications GR 38032 hydrochloride; SN 307 hydrochloride	5-HT Receptor	Neurological Disease
Ondansetron hydrochloride (GR 38032 hydrochloride; SN 307 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.

HY-A0021R

Palonosetron (hydrochloride) (Standard)	5-HT Receptor	Cardiovascular Disease Cancer
Palonosetron (hydrochloride) (Standard) is the analytical standard of Palonosetron (hydrochloride). This product is intended for research and analytical applications. Palonosetron hydrochloride is a 5-HT3 antagonist that inhibits chemotherapy-induced nausea and vomiting (CINV).

HY-B0068

Azasetron hydrochloride 2 Publications Verification Y-25130 hydrochloride	5-HT Receptor	Neurological Disease
Azasetron (Y-25130) hydrochloride, a benzamide derivative, is a potent and selective 5-HT3 receptor antagonist. Azasetron is used in the study for Chemotherapy-induced nausea and vomiting (CINV) .

HY-14407

Fosaprepitant L-758298	Neurokinin Receptor	Neurological Disease Endocrinology Cancer
Fosaprepitant (L-785298) is a proagent of Aprepitant (HY-10052). Fosaprepitant is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) .

HY-A0021S

Palonosetron-d3 hydrochloride	5-HT Receptor	Cardiovascular Disease
Palonosetron-d₃ (hydrochloride) is the deuterium labeled Palonosetron hydrochloride. Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)[1][2].

HY-B0326

Alibendol	Others	Endocrinology
Alibendol can be taken orally. It has anti-spasmodic properties and promotes bile secretion, making it useful for research on digestive system issues like indigestion, nausea, vomiting, and constipation .

HY-121388

Ledol (+)-Ledol	Fungal	Infection
Ledol ((+)-Ledol) is an antifungal agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting .

HY-14407A

Fosaprepitant dimeglumine 2 Publications Verification MK-0517; L785298	Neurokinin Receptor	Neurological Disease Endocrinology Cancer
Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV) .

HY-B0750S1

Dolasetron-d5 MDL-73147-d₅	5-HT Receptor Isotope-Labeled Compounds	Cancer
Dolasetron-d₅ is deuterated labeled Dolasetron (HY-B0750). Dolasetron (MDL-73147) is a 5-HT3 receptor antagonist with potential for treatment of chemotherapy-induced nausea and vomiting.

HY-B1215

Dimenhydrinate	Histamine Receptor	Neurological Disease Endocrinology
Dimenhydrinate is an orally active H1-antihistamine consisting of Diphenhydramine (HY-B0303) and 8-Chlorotheophylline. Dimenhydrinate is used to prevent nausea, vomiting, dizziness, and vertigo associated with motion sickness .

HY-B0071R

Granisetron (Standard)	5-HT Receptor	Neurological Disease Cancer
Granisetron (Standard) is the analytical standard of Granisetron. This product is intended for research and analytical applications. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B1397S

Cyclizine-d3	Isotope-Labeled Compounds Histamine Receptor	Neurological Disease
Cyclizine-d₃ is deuterium labeled Cyclizine. Cyclizine, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine can be used for the research of nausea, vomiting, and dizziness .

HY-132348S

Granisetron-d3	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Granisetron-d₃ is the deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy[1][2].

HY-14405B

(R)-Casopitant (R)-GW679769	Neurokinin Receptor	Cancer
(R)-Casopitant ((R)-GW679769) is the isomer of Casopitant (HY-14405). Casopitant is a NK(1)-receptor antagonist. Casopitant can be used for the research of chemotherapy-induced nausea and vomiting .

HY-B0071AR

Granisetron (Hydrochloride) (Standard) BRL 43694A (Standard)	5-HT Receptor	Neurological Disease Cancer
Granisetron (Hydrochloride) (Standard) is the analytical standard of Granisetron (Hydrochloride). This product is intended for research and analytical applications. Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B0002BS

Ondansetron-d5 GR 38032-d₅; SN 307-d₅	5-HT Receptor	Neurological Disease
Ondansetron-d₅ is the deuterium labeled Ondansetron. Ondansetron (GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.

HY-17382A

Metoclopramide hydrochloride hydrate 2 Publications Verification	5-HT Receptor Dopamine Receptor	Endocrinology
Metoclopramide hydrochloride hydrate is a potent antagonist of 5-HT₃ and dopamine D2 receptor, with IC₅₀s of 308 nM and 483 nM, respectively. Metoclopramide hydrochloride hydrate can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis .

HY-17382

Metoclopramide 2 Publications Verification	5-HT Receptor Dopamine Receptor	Endocrinology
Metoclopramide is a potent antagonist of 5-HT₃ and dopamine D2 receptor, with IC₅₀s of 308 nM and 483 nM, respectively. Metoclopramide can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis .

HY-B0002S

Ondansetron-d3 hydrochloride	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease
Ondansetron-d₃ (hydrochloride) is the deuterium labeled Ondansetron hydrochloride. Ondansetron hydrochloride (GR 38032 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[1][2].

HY-B0071S1

Granisetron-d4 BRL 43694-d₄	Isotope-Labeled Compounds	Neurological Disease Cancer
Granisetron-d₄ (BRL 43694-d₄) is deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B0071S2

Granisetron-d6 BRL 43694-d₆ (Standard)	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease Cancer
Granisetron-d₆ (BRL 43694-d₆) is deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B0071AS

Granisetron-d6 Hydrochloride BRL 43694A-d₆	Isotope-Labeled Compounds 5-HT Receptor	Neurological Disease Cancer
Granisetron-d₆ (Hydrochloride) (BRL 43694A-d₆) is deuterium labeled Granisetron (Hydrochloride). Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-17382B

Metoclopramide hydrochloride	5-HT Receptor Dopamine Receptor	Neurological Disease
Metoclopramide hydrochloride is a potent and orally active antagonist of 5-HT₃ and dopamine D2 receptor, with IC₅₀s of 308 nM and 483 nM, respectively. Metoclopramide hydrochloride can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis .

HY-118209

L 646462	Dopamine Receptor 5-HT Receptor	Neurological Disease
L-646462 is an antagonist of dopamine and 5-HT, with selectivity for the peripheral system (the central/peripheral activity ratio of L-646462 is 143). L-646462 can be used in research related to nausea, vomiting, and associated neurological disorders .

HY-B0002BS1

Ondansetron-d3 GR 38032-d₃; SN 307-d₃	5-HT Receptor	Neurological Disease
Ondansetron-d₃ is the deuterium labeled Ondansetron[1]. Ondansetron(GR 38032;SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2].

HY-B0002S1

Ondansetron-d6 hydrochloride GR 38032-d₆ hydrochloride; SN 307-d₆ hydrochloride	5-HT Receptor	Neurological Disease
Ondansetron-d₆ (hydrochloride) is the deuterium labeled Ondansetron hydrochloride[1]. Ondansetron hydrochloride is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2][3][4][5][6][7].

HY-14407AS

Fosaprepitant-d4 dimeglumine MK-0517-d₄; L785298-d₄	Isotope-Labeled Compounds Neurokinin Receptor	Neurological Disease Endocrinology Cancer
Fosaprepitant-d₄ (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1].

HY-B0002A

Ondansetron hydrochloride dihydrate 5+ Cited Publications GR 38032 hydrochloride dihydrate; SN 307 hydrochloride dihydrate	5-HT Receptor	Neurological Disease Cancer
Ondansetron (GR 38032) hydrochloride dehydrate is an orally active, highly selective and competitive 5-HT₃ receptor antagonist (crosses the blood-brain barrier). Ondansetron hydrochloride dehydrate can be used in studies of preventing nausea and vomiting associated with cancer chemotherapy, radiation therapy and surgery .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-121388

Ledol (+)-Ledol	Structural Classification Terpenoids Sesquiterpenes Source classification Plants Ericaceae Rhododendron tomentosum Harmaja	Fungal
Ledol ((+)-Ledol) is an antifungal agent that can be isolated from the essential oil fractions of Rhododendron tomentosum. Ledol is also the expectorant and antitussive agent, which is simultaneously responsible for adverse reactions such as dizziness, nausea and vomiting .

HY-N7541R

Antrodin A (Standard)	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	HCV Protease
Metoclopramide (Standard) is the analytical standard of Metoclopramide. This product is intended for research and analytical applications. Metoclopramide is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. Metoclopramide can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis .

HY-B2065

Scopolamine hydrochloride (-)-Scopolamine hydrochloride; Hyoscine hydrochloride	Alkaloids Structural Classification Other Alkaloids Source classification Atropa belladonna Linn. Solanaceae Plants	mAChR 5-HT Receptor
Scopolamine hydrochloride is a non-selective and high affinity (≤1 nM) muscarinic antagonist that is used for the prevention of post-operative nausea and vomiting. Scopolamine readily passes the blood brain barrier. Scopolamine also reversibly inhibits 5-HT3 receptor-responses with an IC₅₀ of 2.09 μM . Scopolamine induces Alzheimer's disease-like pathology through alteration of cholinergic system .

Cat. No.	Product Name	Chemical Structure

HY-B0002BS

Ondansetron-d5
Ondansetron-d₅ is the deuterium labeled Ondansetron. Ondansetron (GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.

HY-B0002S

Ondansetron-d3 hydrochloride
Ondansetron-d₃ (hydrochloride) is the deuterium labeled Ondansetron hydrochloride. Ondansetron hydrochloride (GR 38032 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[1][2].

HY-A0125AS

Alizapride-13C,d3 hydrochloride
Alizapride- ¹³C,d₃ (hydrochloride) is deuterium labeled Alizapride (hydrochloride). Alizapride hydrochloride is a dopamine receptor antagonist with prokinetic and antiemetic effects which can also be used in the treatment of nausea and vomiting, including postoperative nausea and vomiting.

HY-12751S

Trimethobenzamide-d6
Trimethobenzamide-d₆ is deuterium labeled Trimethobenzamide. Trimethobenzamide is a blocker of the D2 receptor. Trimethobenzamide is an antiemetic used to prevent nausea and vomiting.

HY-A0021S

Palonosetron-d3 hydrochloride
Palonosetron-d₃ (hydrochloride) is the deuterium labeled Palonosetron hydrochloride. Palonosetron hydrochloride is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV)[1][2].

HY-B0750S1

Dolasetron-d5
Dolasetron-d₅ is deuterated labeled Dolasetron (HY-B0750). Dolasetron (MDL-73147) is a 5-HT3 receptor antagonist with potential for treatment of chemotherapy-induced nausea and vomiting.

HY-B1397S

Cyclizine-d3
Cyclizine-d₃ is deuterium labeled Cyclizine. Cyclizine, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine can be used for the research of nausea, vomiting, and dizziness .

HY-132348S

Granisetron-d3
Granisetron-d₃ is the deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy[1][2].

HY-B0071S1

Granisetron-d4
Granisetron-d₄ (BRL 43694-d₄) is deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B0071S2

Granisetron-d6
Granisetron-d₆ (BRL 43694-d₆) is deuterium labeled Granisetron. Granisetron (BRL 43694) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B0071AS

Granisetron-d6 Hydrochloride
Granisetron-d₆ (Hydrochloride) (BRL 43694A-d₆) is deuterium labeled Granisetron (Hydrochloride). Granisetron (Hydrochloride) (BRL 43694A) is a serotonin 5-HT3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy.

HY-B0002BS1

Ondansetron-d3
Ondansetron-d₃ is the deuterium labeled Ondansetron[1]. Ondansetron(GR 38032;SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2].

HY-B0002S1

Ondansetron-d6 hydrochloride
Ondansetron-d₆ (hydrochloride) is the deuterium labeled Ondansetron hydrochloride[1]. Ondansetron hydrochloride is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy[2][3][4][5][6][7].

HY-14407AS

Fosaprepitant-d4 dimeglumine
Fosaprepitant-d₄ (dimeglumine) is deuterium labeled Fosaprepitant (dimeglumine). Fosaprepitant dimeglumine (MK-0517) is a proagent of Aprepitant (HY-10052). Fosaprepitant dimeglumine is a neurokinin-1 receptor antagonist, which is development for the prevention of chemotherapy-induced nausea and vomiting (CINV)[1].

HY-17382S

Metoclopramide-d3
Metoclopramide-d₃ is deuterium labeled Metoclopramide. Metoclopramide is a potent antagonist of 5-HT3 and dopamine D2 receptor, with IC50s of 308 nM and 483 nM, respectively. Metoclopramide can be used for the research of nausea and vomiting, gastro-oesophageal reflux, and gastroparesis[1][2].

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