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Results for "

nervous system inhibition

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Natural
Products

2

Isotope-Labeled Compounds

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B1111
    Amitraz

    BTS-27419

    		 Adrenergic Receptor Monoamine Oxidase Parasite Infection Endocrinology
    Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
    Amitraz
  • HY-N1501
    Beta-asarone
    2 Publications Verification

    		 Others Neurological Disease Inflammation/Immunology
    Beta-asarone is a major ingredient of Acorus tatarinowii Schott, penetrates blood brain barrier, with the properties of immunosuppression, central nervous system inhibition, sedation, and hypothermy. Beta-asarone protects against Parkinson’s disease .
    Beta-asarone
  • HY-B1111S1
    Amitraz-d3

    BTS-27419-d3

    		 Isotope-Labeled Compounds Adrenergic Receptor Monoamine Oxidase Parasite Infection Endocrinology
    Amitraz-d3 is the deuterium labeled Amitraz. Amitraz is a non-systemic acaricide and insecticide, with alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis.
    Amitraz-d3
  • HY-B1120S
    Temephos-d12

    Temefos-d12

    		 Parasite Infection
    Temephos-d12 is the deuterium labeled Temephos[1]. Temefos is an organophosphate larvicide, used to treat water infested with disease-carrying insects including mosquitoes, midges, and black fly larvae. Temefos affects the central nervous system through inhibition of cholinesterase, results in death before reaching the adult stage[2][3].
    Temephos-d12
  • HY-129278
    Lunarine

    		Parasite Infection Cardiovascular Disease Neurological Disease
    Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM .
    Lunarine
  • HY-122026
    PF-04802367

    PF-367

    		 GSK-3 Neurological Disease
    PF-04802367 (PF-367) is a highly selective GSK-3 inhibitor with an IC50 of 2.1 nM based on a recombinant human GSK-3β enzyme assay and 1.1 nM based on ADP-Glo assay. PF-04802367 shows desirable central nervous system (CNS) properties and potency. PF-04802367 is equally effective at inhibition of the two known GSK-3 isoforms (GSK-3α and GSK-3β) with IC50 values of 10.0 and 9.0 nM in mobility shift assays, respectively .
    PF-04802367
  • HY-B0900
    Anethole
    1 Publications Verification

    Anise camphor; p-Propenylanisole; Isoestragole

    		 Apoptosis Fungal Bacterial MMP NF-κB Infection Neurological Disease Inflammation/Immunology Cancer
    Anethole is a type of orally active aromatic compound that is widely found in nature and used as a flavoring agent. Anethole possesses anticancer, anti-inflammatory, antioxidant, antibacterial, antifungal, anesthetic, estrogenic, central nervous system depressant, hypnotic, insecticidal, and gastroprotective effects. Anethole can be used in the study of oxidative stress-related skin diseases and prostate cancer .
    Anethole

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