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Results for "

oncostatin M

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Apoptosis (1) Bradykinin Receptor (1) Interleukin Related (4) STAT (2)
By Research Areas:	Cancer (4) Endocrinology (1) Inflammation/Immunology (4)
Oligonucleotides:	Aptamers (2)

Inhibitors & Agonists

Peptides

Inhibitory Antibodies

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-33354

Nitrochin 4-NQO	Apoptosis	Cancer
Nitrochin (4-NQO) is a chemical carcinogen. Nitrochin induces oncostatin-M (OSM) in esophageal cells. Nitrochin induces DNA damage, and induces apoptosis via a p53-dependent mitochondrial signaling pathway .

HY-148692

OSM-SMI-10B	STAT	Cancer
OSM-SMI-10B a derivative of OSM-SMI-10. OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) .

HY-P99519

Vixarelimab 1 Publications Verification KPL-716	Interleukin Related	Inflammation/Immunology
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash .

HY-103291

Sar-[D-Phe8]-des-Arg9-Bradykinin	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

HY-113790

ISX-1	Others	Others
ISX-1 is an isoxazole. ISX-1 has anti-adipogenic and pro-osteogenic activities. ISX-1 can be used for the research of osteopenia and osteoporosis .

HY-148695B

ADR58 sodium	Interleukin Related	Inflammation/Immunology
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

HY-148695C

Truncated ADR58 sodium	Interleukin Related	Inflammation/Immunology
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

HY-148693

OSM-SMI-8 NSC642624	Interleukin Related	Cancer
OSM-SMI-8 (NSC642624) is a potent *OSM (oncostatin* M)** antagonist. OSM-SMI-8 has the potential for the research of cancer .

HY-148692A

(E/Z)-OSM-SMI-10B	STAT	Cancer
(E/Z)-OSM-SMI-10B a derivative of OSM-SMI-10. (E/Z)-OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) .

Cat. No.	Product Name	Target	Research Area

HY-103291

Sar-[D-Phe8]-des-Arg9-Bradykinin	Bradykinin Receptor	Inflammation/Immunology Endocrinology
Sar-[D-Phe8]-des-Arg9-Bradykinin is a agonist of B1 receptor. Sar-[D-Phe8]-des-Arg9-Bradykinin selectively amplifies the contractile response when incubation with human recombinant interleukin-1 β (IL-1 β) in rabbit aortic rings .

Cat. No.	Product Name	Target	Research Area

HY-P99519

Vixarelimab 1 Publications Verification KPL-716	Interleukin Related	Inflammation/Immunology
Vixarelimab (KPL-716) is a human anti-oncostatin M (OSM) monoclonal antibody that binds to the beta chain of the OSM receptor and inhibits IL-31 and OSM signalling. Vixarelimab can be used in studies of inflammatory skin diseases such as atopic dermatitis and itchy nodular rash .

Species:	Human (9) Mouse (3) Cynomolgus (1) Canine (1)
Tag:	His (9) Tag Free (5) Avi (2)
Source:	HEK293 (9) E. coli (5)

Cat. No.	Compare	Product Name	Species	Source

HY-P74662

	OSM Protein, Human (HEK293) oncostatin M; OSM	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (HEK293) is the recombinant human-derived OSM protein, expressed by HEK293 , with tag free. The total length of OSM Protein, Human (HEK293) is 196 a.a., with molecular weight of ~31.6 kDa.

HY-P73331

	OSM Protein, Human (HEK293, His) oncostatin M; OSM	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (HEK293, His) is the recombinant human-derived OSM protein, expressed by HEK293 , with C-His labeled tag. The total length of OSM Protein, Human (HEK293, His) is 196 a.a., with molecular weight of 30-40 kDa.

HY-P7275

	OSM Protein, Mouse rMuOSM; oncostatin-M	Mouse	E. coli
	OSM Protein, Mouse is a gp130 cytokine family member, shows homeostatic and proinflammatory activities and can modify extracellular matrix.

HY-P70465

	OSM Protein, Human (His) 2 Publications Verification oncostatin-M; OSM	Human	E. coli
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (His) is the recombinant human-derived OSM protein, expressed by E. coli , with N-6*His labeled tag. The total length of OSM Protein, Human (His) is 196 a.a., with molecular weight of ~24 kDa.

HY-P7274

	OSM Protein, Mouse (HEK293) 1 Publications Verification rMuOSM; oncostatin-M	Mouse	HEK293
	OSM Protein, Mouse (HEK293) is a gp130 cytokine family member, shows homeostatic and proinflammatory activities and can modify extracellular matrix.

HY-P700805

	OSM Protein, Mouse (HEK293, His) oncostatin M; OSM; MGC20461; oncostatin-M	Mouse	HEK293
	OSM protein is a multifunctional growth regulator that effectively inhibits the proliferation of tumor cell lines and regulates the production of cytokines, including IL-6, G-CSF, and GM-CSF produced by endothelial cells.It specifically binds to type II OSM receptors, forming a heterodimer composed of OSMR and IL6ST.OSM Protein, Mouse (HEK293, His) is the recombinant mouse-derived OSM protein, expressed by HEK293 , with C-His labeled tag.

HY-P70465G

	GMP OSM Protein, Human (His) oncostatin-M; OSM	Human	E. coli
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. GMP OSM Protein, Human (His) is the recombinant human-derived OSM protein, expressed by E. coli , with N-6*His labeled tag. The total length of GMP OSM Protein, Human (His) is 196 a.a., with molecular weight of ~28.0 kDa.

HY-P78502

	OSM Protein, Human (HEK293, His-Avi) oncostatin M; OSM; MGC20461	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (HEK293, His-Avi) is the recombinant human-derived OSM protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of OSM Protein, Human (HEK293, His-Avi) is 196 a.a., with molecular weight of 30-40 kDa.

HY-P703730

	Oncostatin M/OSM Protein, Cynomolgus (HEK293, His)	Cynomolgus	HEK293

HY-P703755

	Oncostatin M/OSM Protein Protein, Canine (HEK293, His)	Canine	HEK293

HY-P78187

	OSM Protein, Human (Biotinylated, HEK293, His-Avi) oncostatin M; OSM; MGC20461	Human	HEK293
	OSM protein is a multifunctional growth regulator with dual functions of inhibiting tumor cell lines and stimulating the proliferation of AIDS-KS cells. It coordinates the production of cytokines, including IL-6, G-CSF, and GM-CSF, and binds to type I and type II OSM receptors, forming heterodimers with LIFR/IL6ST and OSMR/IL6ST, respectively. OSM Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived OSM protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of OSM Protein, Human (Biotinylated, HEK293, His-Avi) is 196 a.a., with molecular weight of 30-40 kDa.

HY-P7052

	OSM Protein, Human (227a.a) 1 Publications Verification rHuOSM; OSM	Human	E. coli
	OSM Protein, Human (227a.a) is a polypeptide chain containing 227 amino acids. Oncostatin M is a cytokine belonging to the IL-6 family that has multiple functions in hematopoiesis, mesenchymal stem cell differentiation, liver regeneration, heart remodeling, nociception, inflammation and metabolism.

HY-P7052A

	OSM Protein, Human (209a.a) rHuOSM; OSM	Human	E. coli
	OSM Protein, Human (209a.a) is a polypeptide chain containing 209 amino acids. Oncostatin M is a cytokine belonging to the IL-6 family that has multiple functions in hematopoiesis, mesenchymal stem cell differentiation, liver regeneration, heart remodeling, nociception, inflammation and metabolism.

HY-P72500

	OSMR beta Protein, Human (HEK293, His) oncostatin-M-specific receptor subunit beta; IL-31R-beta; IL-31RB; OSMR; OSMRB	Human	HEK293
	The OSMR beta protein is critical in immune responses by binding to IL12RB1 to form the interleukin 23 receptor with IL-23R. It binds to IL23 and activates T cells, NK cells and potentially macrophages/myeloid cells through Jak-Stat signaling. OSMR beta Protein, Human (712a.a, HEK293, His) is the recombinant human-derived OSMR beta protein, expressed by HEK293 , with C-6*His labeled tag. The total length of OSMR beta Protein, Human (712a.a, HEK293, His) is 712 a.a., with molecular weight of ~132 kDa.

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HY-P83068

	Oncostatin M Antibody (YA2813) oncostatin-M (OSM)	WB	Human, Mouse, Rat
	Oncostatin M Antibody (YA2813) is a biotin-conjugated non-conjugated IgG antibody, targeting Oncostatin M, with a predicted molecular weight of 28 kDa (observed band size: 22 kDa). Oncostatin M Antibody (YA2813) can be used for WB experiment in human, mouse, rat background.

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Cat. No.	Product Name		Classification

HY-148695B

ADR58 sodium		Aptamers
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

HY-148695C

Truncated ADR58 sodium		Aptamers
ADR58 sodium is a highly potent and selective human oncostatin M (OSM) antagonist, which can prevent the binding of OSM to the gp130 receptor and specifically antagonize OSM-mediated signaling. ADR58 sodium can be used in the research of rheumatoid arthritis related diseases .

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