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Results for "

pain suppressing

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Adrenergic Receptor (2) Aldehyde Dehydrogenase (ALDH) (2) Apoptosis (2) Bacterial (3) Biochemical Assay Reagents (1) Bradykinin Receptor (1) Calcium Channel (3) Cannabinoid Receptor (2) COX (2) Drug Metabolite (1) Endogenous Metabolite (3) ERK (1) Ferroptosis (3) Fungal (2) GABA Receptor (3) Histamine Receptor (3) Histone Methyltransferase (1) iGluR (1) Isotope-Labeled Compounds (2) MEK (1) NF-κB (5) NO Synthase (4) NOD-like Receptor (NLR) (4) P2X Receptor (1) PGE synthase (2) Phosphodiesterase (PDE) (1) Prostaglandin Receptor (1) Sigma Receptor (1) Sodium Channel (12)
By Research Areas:	Cancer (10) Cardiovascular Disease (4) Endocrinology (1) Infection (3) Inflammation/Immunology (13) Metabolic Disease (2) Neurological Disease (32)

By Targets:

Adrenergic Receptor (2)

Aldehyde Dehydrogenase (ALDH) (2)

Apoptosis (2)

Bacterial (3)

Biochemical Assay Reagents (1)

Bradykinin Receptor (1)

Calcium Channel (3)

Cannabinoid Receptor (2)

COX (2)

Drug Metabolite (1)

Endogenous Metabolite (3)

ERK (1)

Ferroptosis (3)

Fungal (2)

GABA Receptor (3)

Histamine Receptor (3)

Histone Methyltransferase (1)

iGluR (1)

Isotope-Labeled Compounds (2)

MEK (1)

NF-κB (5)

NO Synthase (4)

NOD-like Receptor (NLR) (4)

P2X Receptor (1)

PGE synthase (2)

Phosphodiesterase (PDE) (1)

Prostaglandin Receptor (1)

Sigma Receptor (1)

Sodium Channel (12)

By Research Areas:

Cancer (10)

Cardiovascular Disease (4)

Endocrinology (1)

Infection (3)

Inflammation/Immunology (13)

Metabolic Disease (2)

Neurological Disease (32)

Inhibitors & Agonists

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B2080A

Etidocaine hydrochloride 1 Publications Verification EDC hydrochloride	Others	Infection Others
Etidocaine (hydrochloride) is a long aminoamide local agent that can suppress or relieve pain .

HY-108068

Alphadolone acetate Alfadolone acetate; GR 2/1574	GABA Receptor	Neurological Disease
Alphadolone acetate (Alfadolone acetate) is a steroid agent that can suppress or relieve pain, with antinociception .

HY-W275039

Phenylquinone 2-Phenylbenzoquinone	Biochemical Assay Reagents	Neurological Disease
Phenylquinone (2-Phenylbenzoquinone) causes pain and induces writhing in mice, and is often used in experiments to test the effectiveness of analgesics or agent that can suppress or relieve pain .

HY-W016083

Anavenol β-Naphthoxyethanol	Others	Others
Anavenol (β-Naphthoxyethanol) is an agent that can suppress or relieve pain, used for horses .

HY-W005637

Orthocaine	Others	Neurological Disease
Orthocaine is a local agent that can suppress or relieve pain (extracted from patent WO2002089849A1) .

HY-19646

Zoliprofen 480156-S	Bradykinin Receptor Prostaglandin Receptor	Neurological Disease
Zoliprofen (480156-S), a new non-steroidal anti-inflammatory agent, has potent pain suppressing effect. Zoliprofen has strong antagonistic action against bradykinin, markedly inhibiting all bradykinin-induced edema and pain reactions. Zoliprofen weakly inhibits Arachidonic acid (HY-109590)-induced edema and pain reactions but also inhibits PGE2 synthesis of bovine vesicular gland microsomes .

HY-W694291

Clibucaine	Others	Others
Clibucaine is a piperidine derivative possessing local agent that can suppress or relieve pain. Clibucaine can be used as a local agent that can suppress or relieve pain .

HY-105613

Metabutoxycaine	Others	Others
Metabutoxycaine is a local agent that can suppress or relieve pain .

HY-105631

Hydroxytetracaine Salicaine	Others	Neurological Disease
Hydroxytetracaine is a local agent that can suppress or relieve pain .

HY-156061

NAP-1	GABA Receptor	Neurological Disease Inflammation/Immunology
NAP-1 is a compound with agent that can suppress or relieve pain. effects. NAP-1 enhances the inhibitory current by binding to a specific site of GABAaR, resulting in a narcotic effect. NAP-1 can be used in research to develop clinical agent that can suppress or relieve pain .

HY-105584

Tolycaine	Others	Neurological Disease
Tolycaine is a local agent that can suppress or relieve pain. Tolycaine also induces a convulsive response in experimental animals .

HY-106495

Vadocaine OR K-242	Others	Neurological Disease
Vadocaine (OR K-242), an orally active antitussive compound, is a local agent that can suppress or relieve pain .

HY-B1656

Fomocaine P 652	Others	Cardiovascular Disease Neurological Disease
Fomocaine (P 652) is an orally active local agent that can suppress or relieve pain. Fomocaine shows antiarrhythmic activity .

HY-W011777S

Tricaine-d5 methanesulfonate MS-222-d₅	Isotope-Labeled Compounds	Neurological Disease
Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish .

HY-101437

Ralfinamide 1 Publications Verification FCE-26742A	Sodium Channel	Neurological Disease
Ralfinamide (FCE-26742A) is an orally available Na ⁺ blocker derived from α-aminoamide, with function of suppressing pain .

HY-101437A

Ralfinamide mesylate FCE-26742A mesylate	Sodium Channel	Neurological Disease
Ralfinamide mesylate (FCE-26742A mesylate) is an orally available Na ⁺ channel blocker derived from α-aminoamide, with function of suppressing pain .

HY-107915

Levonordefrin (-)-Cobefrin; (-)-α-Methylnoradrenaline; (-)-Nordefrin	Adrenergic Receptor	Others
Levonordefrin, a common alternative to levoepinephrine as a vasoconstrictor in dental local agent that can suppress or relieve pain, is usually used in fivefold higher concentrations. Levonordefrin is generally considered equivalent to epinephrine .

HY-148157

Amylocaine	Others	Others
Amylocaine is a local agent that can suppress or relieve pain of the ester type. Amylocaine can cause reversible insensitization near the area where it is administered. Amylocaine is used mostly in spinal anesthesia .

HY-107040

Etoxadrol NSC 288020; CL-1848C	iGluR	Others
Etoxadrol (CL-1848C) is a potent, high-affinity N-methyl-D-aspartic acid (NMDA) antagonist. Etoxadrol is used in the anaesthetic and anaesthesia research community to suppress or relieve pain .

HY-116457

Propanidid Sombrevin; Fabantol	GABA Receptor	Cardiovascular Disease Neurological Disease
Propanidid (Sombrevin; Fabantol) is a γ-aminobutyric acid type A (GABA_A) receptor agonist and a short-acting non-barbiturate general agent that can suppress or relieve pain. Propanidid can decrease the arterial pressure .

HY-B1726

Phenacaine Holocaine	Phosphodiesterase (PDE)	Metabolic Disease
Phenacaine (Holocaine) is a local agent that can suppress or relieve pain. Phenacaine inhibits the specific calmodulin-dependent stimulation of erythrocyte Ca ²⁺-ATPase and cyclic nucleotide phosphodiesterases from brain and heart .

HY-147306A

(S)-ZLc002	NO Synthase	Neurological Disease
(S)-ZLc002 is a S-enantiomer of ZLc-002. ZLc-002 is a selective inhibitor of nNOS-Capon coupling. ZLc-002 suppresses inflammatory nociception and chemotherapy-induced neuropathic pain .

HY-121103

Aclantate	Histone Methyltransferase	Inflammation/Immunology
Aclantate is a nonsteroidal anti-inflammatory drug with anti-inflammatory and analgesic activity. Aclantate is mainly used to relieve various types of pain and reduce inflammatory responses. Aclantate can be used to suppress rheumatoid arthritis and other related diseases .

HY-B0653A

Levobupivacaine hydrochloride 2 Publications Verification (S)-(-)-Bupivacaine monohydrochloride	Sodium Channel Ferroptosis	Cardiovascular Disease Neurological Disease Cancer
Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local agent that can suppress or relieve pain. Levobupivacaine hydrochloride exerts agent that can suppress or relieve pain. and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer .

HY-B0653

Levobupivacaine (S)-(-)-Bupivacaine	Sodium Channel Ferroptosis	Neurological Disease Cancer
Levobupivacaine ((S)-(-)-Bupivacaine) is a long-acting amide local agent that can suppress or relieve pain. Levobupivacaine exerts agent that can suppress or relieve pain. and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer .

HY-B0516

Articaine hydrochloride Hoe-045	Sodium Channel NF-κB NOD-like Receptor (NLR)	Neurological Disease
Articaine hydrochloride (Hoe-045) is an amide agent that can suppress or relieve pain, containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway .

HY-151451

Cav 3.2 inhibitor 2	Calcium Channel	Neurological Disease
Cav 3.2 inhibitor 2 is a Ca_v3.2 T-type Ca ²⁺ channels inhibitor with an IC₅₀ of 0.09339 μM under -80mV holding potential. Cav 3.2 inhibitor 2 potently suppresses T-channel-dependent somatic and visceral pain in mice. Cav 3.2 inhibitor 2 can be used for the research of intractable pain .

HY-118756

Anirolac RS37326	Endogenous Metabolite	Inflammation/Immunology
Anirolac (RS37326) is a nonsteroidal anti-inflammatory agent with analgesic activity. Anirolac showed analgesic efficacy comparable to that of naproxen in suppressing moderate or severe postpartum uterine pain. Anirolac induced significantly higher analgesia scores than placebo within 6 hours, especially at the 100 mg dose. Anirolac effectively relieved pain and showed a stronger analgesic effect than placebo in every assessment .

HY-147306

ZLc-002	Others	Neurological Disease
ZLc-002 is a selective inhibitor of nNOS-Capon coupling. ZLc-002 suppresses inflammatory nociception and chemotherapy-induced neuropathic pain. ZLc-002 can be used for the research of anxiety disorder and inflammation .

HY-B0364A

Dyclonine hydrochloride 1 Publications Verification Dyclocaine hydrochloride	Bacterial Fungal Aldehyde Dehydrogenase (ALDH)	Infection Cancer
Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC₅₀ of 35 μM for ALDH2 and 76 μM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local agent that can suppress or relieve pain. that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain .

HY-B0516A

Articaine Hoe-045 free base	NF-κB NOD-like Receptor (NLR) Sodium Channel	Inflammation/Immunology
Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway .

HY-A0140

Drotaverine	Others	Neurological Disease
Drotaverine is a selective phosphodiesterase 4 inhibitor with angina relief activity. Drotaverine is used to suppress angina, including pain in the gastrointestinal tract and biliary tract. Drotaverine may also cause compound-induced priapism, a side effect of sustained penile erection .

HY-107915R

Levonordefrin (Standard)	Adrenergic Receptor	Others
Levonordefrin (Standard) is the analytical standard of Levonordefrin. This product is intended for research and analytical applications. Levonordefrin, a common alternative to levoepinephrine as a vasoconstrictor in dental local agent that can suppress or relieve pain, is usually used in fivefold higher concentrations. Levonordefrin is generally considered equivalent to epinephrine .

HY-110036

GW-405833 L768242	Cannabinoid Receptor	Neurological Disease Inflammation/Immunology
GW-405833 (L768242) is a potent, selective cannabinoid receptor 2 (CB₂) agonist with an EC₅₀ of 50.7 nM. GW-405833 also behaves as a noncompetitive CB₁ antagonist. GW-405833 suppresses inflammatory and neuropathic pain .

HY-B0516R

Articaine (hydrochloride) (Standard) Hoe-045 (Standard)	Sodium Channel NF-κB NOD-like Receptor (NLR)	Neurological Disease
Articaine (hydrochloride) (Standard) is the analytical standard of Articaine (hydrochloride). This product is intended for research and analytical applications. Articaine hydrochloride (Hoe-045) is an amide agent that can suppress or relieve pain， containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-?B activation and the NLRP3 inflammasome pathway .

HY-124996

(Rac)-ZLc-002	NO Synthase	Neurological Disease Inflammation/Immunology Cancer
(Rac)-ZLc-002, an inhibitor of nNOS interaction with nitric oxide synthase 1 adaptor protein (NOS1AP), suppresses inflammatory nociception and chemotherapy-induced neuropathic pain and synergizes with Paclitaxel (HY-B0015) to reduce tumor cell viability .

HY-108903A

Hyaluronidase, Ovine testes 5 Publications Verification	Endogenous Metabolite	Metabolic Disease
Hyaluronidase, Ovine testes is an enzyme responsible for catalyzing the degradation of hyaluronic acid. It is used to improve the absorption and dispersion of gastrointestinal fluids, drugs, and contrast agents. Hyaluronidase, Ovine testes can enhance the diffusion or delivery of local agent (LA) that can suppress or relieve pain or immunoglobulins (Igs) .

HY-B0653AS

Levobupivacaine-d9 hydrochloride (S)-(–)-Bupivacaie-d₉(hydrochloride)	Isotope-Labeled Compounds Ferroptosis Sodium Channel	Cardiovascular Disease Neurological Disease Cancer
Levobupivacaine-d₉ ((S)-(–)-Bupivacaie-d₉) hydrochloride is deuterium labeled Levobupivacaine (hydrochloride). Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local agent that can suppress or relieve pain. Levobupivacaine hydrochloride exerts agent that can suppress or relieve pain. and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer .

HY-13988

AT-56	PGE synthase	Inflammation/Immunology
AT-56 is a potent, selective and orally active inhibitor of lipocalin-type prostaglandin D synthase (L-PGDS), with an IC₅₀ of 95 μM and K_i of 75 μM. AT-56 could selectively suppress the drowsiness or pain reaction mediated by L-PGDS-catalyzed PGD₂ .

HY-W671745

Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside	Others	Others
Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside (MFLNH I) (compound 5) can be isolated from the seed kernel of Entada rheedei. Entada rheedei is a medicinal plant from Thailand that is used to suppress stomach pain .

HY-110036A

GW405833 hydrochloride L768242 hydrochloride	Cannabinoid Receptor	Neurological Disease
GW-405833 (L768242) hydrochloride is a potent, selective cannabinoid receptor 2 (CB₂) agonist with an EC₅₀ of 50.7 nM. GW-405833 hydrochloride also behaves as a noncompetitive CB₁ antagonist. GW-405833 hydrochloride suppresses inflammatory and neuropathic pain .

HY-N1478

Gardenoside	P2X Receptor	Neurological Disease
Gardenoside is a natural compound found in Gardenia fruits, with hepatoprotective properties. Gardenoside suppresses the pain of chronic constriction injury by regulating the P2X3 and P2X7 receptors. Gardenoside has an inhibitory effect on free fatty acids (FFA)-induced cellular steatosis .

HY-W357818

Glycinexylidide GX	Sodium Channel ERK MEK NF-κB Drug Metabolite	Cancer
Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease .

HY-B0364AR

Dyclonine (hydrochloride) (Standard)	Bacterial Fungal Aldehyde Dehydrogenase (ALDH)	Infection Cancer
Dyclonine (hydrochloride) (Standard) is the analytical standard of Dyclonine (hydrochloride). This product is intended for research and analytical applications. Dyclonine (Dyclocaine) hydrochloride is an orally effective ALDH covalent inhibitor (crosses blood-brain barrier), with an IC_{50_{of 35 μM for ALDH2 and 76 μM for ALDH3A1. Dyclonine hydrochloride has sensitizing activities for targeted cancer cells and antibacterial. Dyclonine hydrochloride is also a local agent that can suppress or relieve pain. that blocks the transmission of various nerve impulses or stimuli and inhibits the sensation of touch and pain .}}

HY-B0516AR

Articaine (Standard)	NF-κB NOD-like Receptor (NLR) Sodium Channel	Inflammation/Immunology
Articaine (Standard) is the analytical standard of Articaine. This product is intended for research and analytical applications. Articaine (Hoe-045 free base) is an amide agent that can suppress or relieve pain. containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine ameliorates LPS-induced acute kidney injury via inhibition of NF-κB activation and the NLRP3 inflammasome pathway .

HY-B0971

Pheniramine maleate Prophenpyridamine maleate; Tripoton maleate; Pheniramine maleate	Histamine Receptor Apoptosis	Inflammation/Immunology Endocrinology
Pheniramine (Prophenpyridamine; Tripoton) maleate is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine maleate displays antitumor effect and induces leukemia cells apoptosis. Pheniramine maleate is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-B0971A

Pheniramine Prophenpyridamine; Tripoton; Pheniramine solution	Histamine Receptor Apoptosis	Inflammation/Immunology Cancer
Pheniramine (Prophenpyridamine;Tripoton) is a first-generation histamine H1 receptor antagonist, acts on the central nervous system (CNS) with sedative and hypnotic effect. Pheniramine displays antitumor effect and induces leukemia cells apoptosis. Pheniramine is also a safe and effective local agent that can suppress or relieve pain, with antipruritic effects .

HY-169430

AGU654	PGE synthase
AGU654 (Compound 44) is a selective mPGES-1 inhibitor with an IC₅₀ of 2.9 nM against mPGES-1. AGU654 inhibits mPGES-1 to block the pathway converting arachidonic acid into prostaglandin E2 (PGE2) by COX-1/2, thereby alleviating inflammatory responses, pain, and fever. In activated human monocyte-derived macrophages and human whole blood models, AGU654 selectively suppresses bacterial exotoxin-induced PGE2 production while preserving the production of other prostaglandins. In guinea pig models, AGU654 significantly alleviates fever, inflammation, and inflammatory pain, exhibiting excellent anti-inflammatory, analgesic, and antipyretic effects. AGU654 holds promise as a strategy for studying inflammatory diseases and pain .

HY-Y0258A

Benzocaine hydrochloride 1 Publications Verification	Bacterial Sodium Channel	Neurological Disease
Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain, that acts on voltage-gated Na ⁺ channels at a common receptor, with an IC₅₀ value of 0.8 mM at +30 mV. Additionally, Benzocaine (hydrochloride) non-competitively inhibits Ca-ATPase binding with Ca ²⁺, with an IC₅₀ of 47.1 mM. Benzocaine (hydrochloride) can be used in research within the field of neuromuscular regulation .

HY-P5900

m3-Huwentoxin IV m3-HwTx-IV	Sodium Channel	Neurological Disease
m3-Huwentoxin IV (m3-HwTx-IV) is a potent Na_V inhibitor with IC₅₀s of 3.3, 6.8, 7.2, 8.4, 11.9 and 369 nM against hNa_V1.7, hNa_V1.6, hNa_V1.3, hNa_V1.1, hNa_V1.2 and hNa_V1.4, respectively in QPatch assay. m3-Huwentoxin IV dose-dependently suppresses spontaneous pain induced by the Na_V1.7 activator OD1 in a rodent pain model .

Cat. No.	Product Name	Type

HY-W357818

Glycinexylidide GX	Biochemical Assay Reagents
Glycinexylidide (GX) is the active metabolite of Lidocaine. Lidocaine is a local agent that can suppress or relieve pain, that inhibits sodium channels involving complex voltage and dependence. Lidocaine also reduces the growth, migration and invasion of gastric cancer cells. Glycinexylidide has research potential for use in anesthesia, cancer, and cardiovascular disease .

Cat. No.	Product Name	Target	Research Area

HY-P2428

RI-61	Peptides	Neurological Disease
RI-61 is a compound that has activity in suppressing migraine, cluster headache, new daily persistent headache and cyclical vomiting syndrome. RI-61 has shown significant efficacy in relieving the symptoms of these disorders. RI-61 helps relieve pain and other related symptoms by modulating the action of neurotransmitters .

HY-P5900

m3-Huwentoxin IV m3-HwTx-IV	Sodium Channel	Neurological Disease
m3-Huwentoxin IV (m3-HwTx-IV) is a potent Na_V inhibitor with IC₅₀s of 3.3, 6.8, 7.2, 8.4, 11.9 and 369 nM against hNa_V1.7, hNa_V1.6, hNa_V1.3, hNa_V1.1, hNa_V1.2 and hNa_V1.4, respectively in QPatch assay. m3-Huwentoxin IV dose-dependently suppresses spontaneous pain induced by the Na_V1.7 activator OD1 in a rodent pain model .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-N1478

Gardenoside	Structural Classification Iridoids Terpenoids Source classification Rubiaceae Plants Gardenia jasminoides Ellis	P2X Receptor
Gardenoside is a natural compound found in Gardenia fruits, with hepatoprotective properties. Gardenoside suppresses the pain of chronic constriction injury by regulating the P2X3 and P2X7 receptors. Gardenoside has an inhibitory effect on free fatty acids (FFA)-induced cellular steatosis .

HY-N0396

Harpagoside 1 Publications Verification	Structural Classification Iridoids Classification of Application Fields Terpenoids Pedaliaceae Plants Harpagophytum procumbens Inflammation/Immunology Disease Research Fields	COX NO Synthase
Harpagoside can be obtained by Harpagophytum procumbens, which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ) .

HY-W671745

Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside	Structural Classification Polysaccharides Petasites formosanus Kitam. Leguminosae Source classification Plants Saccharides	Others
Entadamide A 2'-O-(6''-O-β-D-glucopyranosyl)-β-D-glucopyranoside (MFLNH I) (compound 5) can be isolated from the seed kernel of Entada rheedei. Entada rheedei is a medicinal plant from Thailand that is used to suppress stomach pain .

HY-N0396R

Harpagoside (Standard)	Structural Classification Iridoids Terpenoids Pedaliaceae Plants Harpagophytum procumbens	COX NO Synthase
Harpagoside (Standard) is the analytical standard of Harpagoside. This product is intended for research and analytical applications. Harpagoside can be obtained by Harpagophytum procumbens, which has anti-inflammatory, anti-cancer, protective activity, and efficacy. Harpagoside has an inhibitory effect on COX-1 and COX-2 active, and suppresses NO production. Harpagoside inhibits HepG2 cell lipid polysaccharide, which is a protein that is expressed horizontally and selectively, and has anti-inflammatory and latent pain effects. Harpagoside has the ability to protect the body, and has a degenerative effect on the β-oxidation (Aβ) .

Cat. No.	Product Name	Chemical Structure

HY-W011777S

Tricaine-d5 methanesulfonate
Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish .

HY-B0653AS

Levobupivacaine-d9 hydrochloride

Levobupivacaine-d₉ ((S)-(–)-Bupivacaie-d₉) hydrochloride is deuterium labeled Levobupivacaine (hydrochloride). Levobupivacaine hydrochloride ((S)-(-)-Bupivacaine monohydrochloride) is a long-acting amide local agent that can suppress or relieve pain. Levobupivacaine hydrochloride exerts agent that can suppress or relieve pain. and analgesic effects through reversible blockade of neuronal sodium channel. Levobupivacaine hydrochloride can inhibit impulse transmission and conduction in cardiovascular and other tissues, possessing certain cardiac and CNS toxicity. Levobupivacaine hydrochloride is metabolized by hepatic cytochrome P450 (CYP450) enzymes in vivo. Levobupivacaine hydrochloride can also induce ferroptosis by miR-489-3p/SLC7A11 signaling in gastric cancer .

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