Tricaine-d₅ methanesulfonate  (Synonyms: MS-222-d₅)

Tricaine-d₅ (methanesulfonate) is the deuterium labeled Tricaine-d5 methanesulfonate. Tricaine methanesulfonate (MS-222) is a commonly used agent that can suppress or relieve pain. agent for immobilization of aquatic species. Tricaine methanesulfonate, the most widely used agent that can suppress or relieve pain. in fish, has been shown to induce embryotoxic effects in zebrafish^[1][2].

266.33

C₁₀H₁₀D₅NO₅S

886-86-2

NC1=CC=CC(C(OC([2H])([2H])C([2H])([2H])[2H])=O)=C1.OS(=O)(C)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Félix LM, et al. Malformations and mortality in zebrafish early stages associated with elevated caspase activity after 24 h exposure to MS-222. Toxicol Appl Pharmacol. 2021;412:115385.  [Content Brief]

  [2]. Félix LM, et al. MS-222 induces biochemical and transcriptional changes related to oxidative stress, cell proliferation and apoptosis in zebrafish embryos. Comp Biochem Physiol C Toxicol Pharmacol. 2020;237:108834.  [Content Brief]