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Results for "

pathogenic fungi

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (8) Bacterial (3) Beta-lactamase (1) CXCR (2) Cytochrome P450 (1) Drug Isomer (1) Endogenous Metabolite (1) Fluorescent Dye (1) Fungal (30)
By Research Areas:	Cancer (2) Infection (30) Inflammation/Immunology (2) Neurological Disease (2)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-43520

BODIPY-FL	Fluorescent Dye	Others
BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. BODIPY-FL-labeled sphingolipid analogs can be used to investigate sphingolipid internalization, transport, and endocytosis in mouse embryonic stem cells. BODIPY-FL-labeled monoterpenes can quickly penetrate bacteria, mammalian, and fungal cells, allowing for the detection of characteristics of a broad spectrum of Gram-positive and Gram-negative bacteria, as well as pathogenic fungi. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

HY-168188

CYP51-IN-21	Cytochrome P450	Infection
CYP51-IN-21 (Compound A33) is a potent CYP51 inhibitor. CYP51-IN-21 shows excellent antifungal activities against pathogenic fungi and drug-resistant strains. CYP51-IN-21 inhibits the formation of fungal biofilm .

HY-155279

Antifungal agent 73	Fungal	Infection
Antifungal agent 73 (compound A32) is an antifungal agent for azole-resistant candidiasis. Antifungal agent 73 disrupts the fungal cell wall and cell membrane. Antifungal agent 73 shows potent in vivo antifungal activity against pathogenic fungi and fluconazole-resistant strains .

HY-N2573A

Corydalmine hydrochloride L-Corydalmine hydrochloride; TLZ-16-CL	Fungal CXCR	Infection Neurological Disease
Corydalmine hydrochloride inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine hydrochloride acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine hydrochloride alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .

HY-N8474

Pyrenocine A	Others	Others
Pyrenocine A is an acyl phytotoxin isolated from plant pathogenic fungi .

HY-B2056

Triforine CELA W 524	Fungal	Infection Inflammation/Immunology
Triforine (CELA W 524), a systemic fungicide, was shown to display a moderate to distinct fungitoxic activity in vitro towards several pathogenic and non-pathogenic fungi .

HY-N14818

O-Acetylbenzeneamidinocarboxylic acid	Fungal	Infection
O-Acetylbenzeneamidinocarboxylic acid is a fungal metabolite that shows inhibitory to variety of plant pathogenic fungi .

HY-B2056R

Triforine (Standard)	Fungal	Infection Inflammation/Immunology
Triforine (Standard) is the analytical standard of Triforine. This product is intended for research and analytical applications. Triforine (CELA W 524), a systemic fungicide, was shown to display a moderate to distinct fungitoxic activity in vitro towards several pathogenic and non-pathogenic fungi .

HY-120753

Rimocidin	Fungal	Infection
Rimocidin, a polyene macrolide, is an antifungal compound. Rimocidin shows broad‐spectrum antifungal activity against multiple plant‐pathogenic fungi .

HY-19584

Variotin	Fungal	Infection
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .

HY-106371

Siccanin	Antibiotic Fungal	Infection
Siccanin is a succinate dehydrogenase (SDH) inhibitor (IC₅₀=0.9 μM) with species-selective activity. Siccanin also is a antibiotic against pathogenic fungi .

HY-N10311

Neosartoricin B	Fungal	Infection
Neosartoricin B is the secondary metabolite, which can be produced by Aspergillus nidulans. Neosartoricin B may regulate immunomodulatory effects with the host during infection and colonization by pathogenic fungi .

HY-N12201

Funiculosin	Antibiotic Fungal	Infection
Funiculosin is a neutral lipophilic antibiotic that inhibits DNA and RNA viruses. Funiculosin also has antifungal activity. Funiculosin inhibits infections caused by pathogenic fungi in primary chicken embryo fibroblasts .

HY-118699

Indole-3-thio carboxamide	Fungal	Infection
Indole-3-thio carboxamide is an antifungal agent. Indole-3-thio carboxamide is a biotransformation product of Camalexin (HY-119502) by plant pathogenic fungi Botrytis cinerea .

HY-148968

Metham sodium Carbathion	Fungal	Infection
Metham sodium (Carbathion) is a broad-spectrum soil microbial suppressant. Metham sodium controls soil-borne pests and weeds. Metham sodium inhibits weed seeds, plant-parasitic nematodes, plant pathogenic *fungi* and soil insects .

HY-N1300

Shizukanolide F	Fungal	Infection Cancer
Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic *fungi* and anti-metastasis breast cancer .

HY-N11528

Eugenitol 7-Noreugenitin	Others	Infection
Eugenitol (Compound 3) is an antifungal metabolite isolated and purified from Diaporthe eucalyptorum. Eugenitol has inhibitory effect on four plant pathogenic fungi (Alternaria solani, Botrytis cinerea, Fusarium solani and Gibberella saubinettii) .

HY-W774934

Isopyrazam	Fungal
Isopyrazam is a plant protection product with fungal activity. Isopyrazam exhibits excellent disease resistance on crops and effectively inhibits the growth of multiple plant pathogenic fungi. The application of Isopyrazam can significantly improve the yield and quality of crops.

HY-W020043

Pyribencarb	Fungal	Infection
Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome b. Pyribencarb is especially active against *Botrytis cinerea* and *Sclerotinia sclerotirum* .

HY-N10292

Chaetosemin J	Fungal Endogenous Metabolite	Infection
Chaetosemin J, an antifungal metabolite, exhibits inhibitory activity against plant pathogenic fungi Botrytis cinerea, Alternaria solani, Magnaporthe oryzae, and Gibberella saubinettii, with MIC values ranging from 12.5-25 μM .

HY-112176

Kanosamine hydrochloride 2 Publications Verification	Fungal Bacterial Antibiotic	Infection
Kanosamine hydrochloride is an antibiotic which inhibits the growth of plant-pathogenic oomycetes, certain *fungi* and a few bacterial species. Kanosamine inhibits Phytophthora medicaginis M2913 and Aphanomyces euteiches WI-98 with MICs of 25 and 60 μg/mL, respectively.

HY-N14763

3'-O-Decarbamoylirumamycin	Antibiotic Fungal	Infection
3'-O-Decarbamoylirumamycin is a 20-membered macrolide antibiotic produced by Streptomyces subflavus subsp.Irumaensis . 3'-O-Decarbamoylirumamycin has certain inhibitory effect on plant pathogenic fungi such as Piricularia oryzae, and Sclerotinia cinerea .

HY-W774918

Oxaziclomefone	Fungal
Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.

HY-W020043R

Pyribencarb (Standard)	Fungal	Infection
Pyribencarb (Standard) is the analytical standard of Pyribencarb. This product is intended for research and analytical applications. Pyribencarb is a benzylcarbamate-type fungicide, which is active against a wide range of plant pathogenic fungi. Pyribencarb is a potent Qo inhibitor of cytochrome b. Pyribencarb is especially active against Botrytis cinerea and Sclerotinia sclerotirum .

HY-W741555

Dechlorogriseofulvin 7-Dechlorogriseofulvin	Antibiotic Fungal	Infection
Dechlorogriseofulvin (7-Dechlorogriseofulvin) is an antibiotic, and exhibits inhibitory activity against various plant pathogenic fungi. Dechlorogriseofulvin inhibits Botrytis cinerea, Rhizoctonia solani, Pythium ultimum, and Sclerotinia sclerotiorum with MIC of 40.0 µg/ml, 43.9 µg/ml, 81.7 µg/ml, and 28.5 µg/ml, respectively .

HY-162256

Antibacterial agent 184	Fungal	Infection
Antibacterial agent 184 (compound 4j) is a fungal inhibitor that is toxic to the plant pathogenic fungus Sclerotinia sclerotiorum. Antibacterial agent 184 can effectively inhibit Sclerotinia sclerotiorum (IR>97%) .

HY-137085

Antibiotic AB023b	Antibiotic Fungal	Infection
Antibiotic AB023b is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023a (HY-137084). Antibiotic AB023b exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea, Fusarium moniliforme and Pythium ultimum .

HY-137084

Antibiotic AB023a	Antibiotic Fungal	Infection
Antibiotic AB023a is part of macrocyclic pentaene antibiotic complex, forming the main components with Antibiotic AB023b (HY-137085). Antibiotic AB023a exhibits antifungal activity against Candida albicans, and plant pathogenic fungi, Botrytis cinerea (MIC= 5 μg/mL), Fusarium moniliforme and Pythium ultimum .

HY-W774918R

Oxaziclomefone (Standard)	Fungal
Oxaziclomefone (Standard) is the analytical standard of Oxaziclomefone. This product is intended for research and analytical applications. Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.

HY-112101R

Prohydrojasmon (racemate) (Standard)	Drug Isomer	Others
Oxaziclomefone (Standard) is the analytical standard of Oxaziclomefone. This product is intended for research and analytical applications. Oxaziclomefone is a broad-spectrum pesticide with fungal activity. Oxaziclomefone effectively controls a variety of crop diseases and has significant effects against plant pathogenic fungi. Oxaziclomefone is widely used in agriculture to protect crops from diseases and improve crop yield and quality.

HY-129260

Kanosamine 3-Amino-3-deoxyglucose	Fungal	Infection
Kanosamine (3-Amino-3-deoxyglucose) is an antibiotic against Saccharomyces cerevisiae and human pathogenic fungi Candida albicans. Kanosamine exhibits antifungal activity through inhibition of cell wall synthesis and inhibition of GlcN-6-P synthase with phosphorylated kanosamine-6-phosphate in cytoplasma .

HY-N2573

Corydalmine L-Corydalmine; TLZ-16	Fungal CXCR	Infection Neurological Disease
Corydalmine (L-Corydalmine) inhibits spore germination of some plant pathogenic as well as saprophytic fungi . Corydalmine acts as an oral analgesic agent, exhibiting potent analgesic activity . Corydalmine alleviates Vincristine-induced neuropathic pain in mice by inhibiting an NF-κB-dependent CXCL1/CXCR2 signaling pathway .

HY-105751

Kalafungin Kalamycin; U-19718	Antibiotic Bacterial Beta-lactamase Fungal	Infection
Kalafungin is an antibiotic, antimicrobial agent and a β-lactamase inhibitor from marine Streptomyces, with IC₅₀ of 225.37 μM. Kalafungin destroys cell membranes. Kalafungin shows inhibitory activities against a variety of pathogenic fungi, yeasts, protozoa, gram-positive bacteria (such as S. aureus ATCC 33591 and S. aureus ATCC 23591), and, to a lesser extent, gram-negative bacteria .

HY-169684

Vaccarin C	Fungal	Infection Cancer
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC₅₀ values of 3.35 and 5.72 μM, respectively .

HY-170378

Laccase-IN-5	Fungal	Infection
Laccase-IN-5 (Compound 2b) is the inhibitor for Laccase with an IC₅₀ of 0.82 μM. Laccase-IN-5 increases the cell membrane permeability, limits the growth of hyphae, destorys the cell wall, and induces oxidative stress responses. Laccase-IN-5 exhibits antifungal activity against various plant pathogenic fungi and oomycetes, inhibits B. dothidea with an EC₅₀ of 0.96 mg/L .

HY-N11756

Linearmycin A	Bacterial	Infection
Linearmycin A is a polyene antibiotic that has been found in Streptomyces. It is active against the bacteria S. aureus and E. coli (MICs=3.1 and 1.6 μg/disc, respectively), the fungi S. cerevisiae and C. albicans (MICs=0.1 and 1.6 μg/disc, respectively), and the plant pathogenic fungus A. niger in disc assays (MIC=0.2 μg/disc). Linearmycin A induces lysis and degradation of B. subtilis as a component of Streptomyces Mg1 extract.

Cat. No.	Product Name	Type

HY-43520

BODIPY-FL	Fluorescent Dyes/Probes
BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. BODIPY-FL-labeled sphingolipid analogs can be used to investigate sphingolipid internalization, transport, and endocytosis in mouse embryonic stem cells. BODIPY-FL-labeled monoterpenes can quickly penetrate bacteria, mammalian, and fungal cells, allowing for the detection of characteristics of a broad spectrum of Gram-positive and Gram-negative bacteria, as well as pathogenic fungi. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

BODIPY-FL

Fluorescent Dyes/Probes

BODIPY-FL is a green fluorescent dye that can be used to label probes or primers. BODIPY-FL fluorescence can be quenched after interacting with uniquely positioned guanine, making it useful for quantifying specific DNA or RNA molecules. BODIPY-FL-labeled sphingolipid analogs can be used to investigate sphingolipid internalization, transport, and endocytosis in mouse embryonic stem cells. BODIPY-FL-labeled monoterpenes can quickly penetrate bacteria, mammalian, and fungal cells, allowing for the detection of characteristics of a broad spectrum of Gram-positive and Gram-negative bacteria, as well as pathogenic fungi. The maximum absorption wavelength of BODIPY-FL is 505 nm, and the maximum emission wavelength is 513 nm .

Cat. No.	Product Name	Target	Research Area

HY-169684

Vaccarin C	Fungal	Infection Cancer
Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC₅₀ values of 3.35 and 5.72 μM, respectively .

Pyrenocine A	Structural Classification Natural Products Microorganisms Source classification	Others
Pyrenocine A is an acyl phytotoxin isolated from plant pathogenic fungi .

O-Acetylbenzeneamidinocarboxylic acid	Structural Classification Natural Products Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
O-Acetylbenzeneamidinocarboxylic acid is a fungal metabolite that shows inhibitory to variety of plant pathogenic fungi .

Rimocidin	Infection Structural Classification Microorganisms Macrolide Antibiotics Classification of Application Fields Antibiotics Source classification Disease Research Fields	Fungal
Rimocidin, a polyene macrolide, is an antifungal compound. Rimocidin shows broad‐spectrum antifungal activity against multiple plant‐pathogenic fungi .

Variotin	Structural Classification Microorganisms Ketones, Aldehydes, Acids Source classification	Fungal
Variotin is an Anti-Fungal Agent. Variotin has a strong antibiotic activity on dermatophytes such as Trichophyton, Microsporum, and Epidermophyton, and also pathogenic fungi in internal mycosis such as Blastomyces and Cryptococcus .

Neosartoricin B	Structural Classification Microorganisms Source classification Phenols Polyphenols	Fungal
Neosartoricin B is the secondary metabolite, which can be produced by Aspergillus nidulans. Neosartoricin B may regulate immunomodulatory effects with the host during infection and colonization by pathogenic fungi .

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