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Results for "

photocaged

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-164170
    Photocaged DAP

    		Others Others
    Photocaged DAP can be genetically encoded as a protein in mammalian cells. Photocaged DAP can be used as an intermediate to capture biosynthetic acylase .
    Photocaged DAP
  • HY-136276
    DMNB-caged-Serine

    		Amino Acid Derivatives Others
    DMNB-caged-Serine is a photocaged amino acid. DMNB-caged-Serine can be used as a catalytic residue, hydrogen bonding partner or site of post-translational modification. DMNB-caged-Serine can be used for the control of protein phosphorylation .
    DMNB-caged-Serine
  • HY-169973
    PhoPS

    		Beta-lactamase Bacterial Infection
    PhoPS is the photocaged inhibitor for β-lactamase. PhoPS is activated upon light irradiation, and active β-lactamase inhibitor Sulbactam (HY-B0334) is released. PhoPS inhibits the synthesis of bacterial cell wall and the formation of E. coli biofilm, exhibits antimicrobial activity .
    PhoPS
  • HY-169217
    CYP3A4-IN-4

    		Cytochrome P450 Cancer
    CYP3A4-IN-4 (compound Δ,Λ-3), a Ru(II)−Ir(III) Conjugate, is a photoactive inhibitor of the major human drug metabolizing enzyme CYP3A4. CYP3A4-IN-4 containing the [Ru(tpy)(Me2bpy)] photocaging group showed an IC50 of 2.2 μM for inhibition of microsomal CYP3A4 under light conditions (λirr=530 nm, tirr=15 min). CYP3A4-IN-4 shows the phototherapeutic index (PI) for of 5.4 .
    CYP3A4-IN-4
  • HY-159110
    ABA-DMNB

    		Others Others
    ABA-DMNB is a photo-caged chemically induced proximity (CIP) inducer. ABA-DMNB is a photo-caged ABA (Abscisic acid (HY-100560)). ABA-DMNB can be uncaged under light irradiation and generate active ABA .
    ABA-DMNB
  • HY-149328
    phoBET1

    		PROTACs Cancer
    phoBET1 is a photocaged-PROTAC. phoBET1 can achieve BRD4 degradation and effectively suppress tumor growth .
    phoBET1
  • HY-W736950
    H-L-Cys(MDNPE)-OH

    		Others Others
    HL-Cys(MDNPE)-OH (compound 2) is a genetically encoded photocaged cysteine compound that has the activity to activate TEV protease upon light exposure in mammalian cells.
    H-L-Cys(MDNPE)-OH
  • HY-155730
    PI3K-IN-41

    		PI3K Cancer
    PI3K-IN-41 (compound 2) is a photocaged compound, as well as a photocaged PI3K inhibitor (IC50=18.92 nM) with anticancer properties. PI3K-IN-41 has potential to be used in precisely controlled cancer therapeutics. PI3K-IN-41 exhibits potent PI3K ihibition upon UV light irradiation, and enhances antitumor effect .
    PI3K-IN-41
  • HY-161093
    PROTAC BRD4 Degrader-23

    		PROTACs Cancer
    PROTAC BRD4 Degrader-23 (compound 17) is an effective visible-light-controlled degrader. PROTAC BRD4 Degrader-23 can inhibit tumor cell proliferation under 405 nm light irradiation .
    PROTAC BRD4 Degrader-23
  • HY-131019
    JF-NP-26

    		mGluR Neurological Disease
    JF-NP-26, an inactive photocaged derivative of raseglurant, is the first caged mGlu5 receptor negative allosteric modulator. Uncaging of JF-NP-26 is elicited with light pulses in the visible spectrum (405 nm). JF-NP-26 induces light-dependent analgesia in models of inflammatory and neuropathic pain in freely behaving animals .
    JF-NP-26

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