2. Search Result
Search Result
Pathways Recommended: Membrane Transporter/Ion Channel
Results for "

plasma membrane integrity

" in MedChemExpress (MCE) Product Catalog:
Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-151284
    Antifungal agent 38

    		Bacterial Fungal Infection
    Antifungal agent 38 is a geterocyclic disulfide, an antifungal and antibacterial agent. Antifungal agent 38 induces the shrinkage of hyphae, disrupts the integrity of the plasma membrane, and causes the damage and leakage of cell contents .
    Antifungal agent 38
  • HY-151280
    Antifungal agent 37

    		Bacterial Fungal Infection
    Antifungal agent 37 is a geterocyclic disulfide, with antifungal activity .
    Antifungal agent 37
  • HY-130743
    Dieugenol

    Bis-eugenol; Dehydrodieugenol

    		 Parasite Infection
    Dieugenol is a neolignan that has been found in N. leucantha and has antioxidative and antiprotozoal activities. It inhibits the formation of thiobarbituric acid reactive substances (TBARS) and scavenges superoxide anions, but not hydroxyl radicals, in cell-free assays. It has anti-trypanosomal activity against T. cruzi amastigotes and trypomastigotes (IC50s=15.1 and 11.5 μM, respectively) but is cytotoxic to NCTC L-929 fibroblasts with a 50% cytotoxic concentration (CC50) value of 58.2 μM.2 Dieugenol (15 μM) disrupts the integrity of the T. cruzi trypomastigote plasma membrane but does not induce the production of reactive oxygen species (ROS) in trypomastigotes or LPS-stimulated and unstimulated isolated mouse peritoneal macrophages.
    Dieugenol

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: