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Results for "

senolytic

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

2

Peptides

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P4157
    FOXO4-DRI

    		MDM-2/p53 Apoptosis Metabolic Disease
    FOXO4-DRI is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI is a senolytic peptide that induces apoptosis of senescent cells .
    FOXO4-DRI
  • HY-P4157A
    FOXO4-DRI acetate

    		MDM-2/p53 Apoptosis Metabolic Disease
    FOXO4-DRI acetate is a cell-permeable peptide antagonist that blocks the interaction of FOXO4 and p53. FOXO4-DRI acetate is a senolytic peptide that induces apoptosis of senescent cells .
    FOXO4-DRI acetate
  • HY-161088
    Anti-aging agent 1

    		Others Others
    Anti-aging agent 1 (compound 24) is a derivative of piperlongumine (HY-N2329) (PL). Anti-aging agent 1 exhibits a 50-fold enhancement in senolytic activity against senescent WI-38 fibroblasts compared to PL .
    Anti-aging agent 1
  • HY-169265
    BRD-K20733377

    		Bcl-2 Family Others
    BRD-K20733377 is an inhibitor for Bcl-2, and exhibits selective cytotoxicity against senescent cells, that inhibits the viability of Etoposide (HY-13629)-induced IMR-90 senescent cell with an IC50 of 10.7 μM. BRD-K20733377 reduces the mRNA expression of aging-related genes p16, p21 and KI67 in aged mouse model .
    BRD-K20733377

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