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short-term

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25

Inhibitors & Agonists

1

Fluorescent Dye

2

Biochemical Assay Reagents

1

Peptides

3

Natural
Products

4

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145577A
    Lafadofensine (D-(-)-Mandelic acid)

    		Others Neurological Disease
    Lafadofensine D-(-)-Mandelic acid is the monoamines reuptake inhibitor. Lafadofensine D-(-)-Mandelic acid has sufficient effects after short-term administration .
    Lafadofensine (D-(-)-Mandelic acid)
  • HY-113075
    1,5-Anhydrosorbitol

    		Endogenous Metabolite Metabolic Disease
    1,5-Anhydrosorbitol is a short-term marker for glycemic control.
    1,5-Anhydrosorbitol
  • HY-119602
    Rolziracetam

    CI-911

    		 Others Neurological Disease
    Rolziracetam is a nootropic agent of the racetam family and improves short-term memory in rats and monkeys .
    Rolziracetam
  • HY-D0830
    Calcein (tetraethyl ester)

    Fluorexon tetraethyl ester

    		 Fluorescent Dye Others
    Calcein tetraethyl ester is a fluorescent dye, is used in biology as it can be transported through the cellular membrane into live cells, which makes it useful for testing of cell viability and for short-term labeling of cells.
    Calcein (tetraethyl ester)
  • HY-14789
    (R)-Elagolix

    NBI-56418

    		 GnRH Receptor Nuclear Factor of activated T Cells (NFAT) Endocrinology Cancer
    Elagolix is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
    (R)-Elagolix
  • HY-14369
    Elagolix sodium

    NBI-56418 sodium

    		 GnRH Receptor Nuclear Factor of activated T Cells (NFAT) Endocrinology Cancer
    Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (KD = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. .
    Elagolix sodium
  • HY-14263
    Pericyazine

    Propericiazine; RP 8909

    		 Dopamine Receptor Neurological Disease
    Pericyazine (Propericiazine) is a first-generation antipsychotic agent that is used as an adjunct to the short-term management of severe anxiety states and psychosis . Pericyazine is a selective D2-dopamine receptor antagonist . Pericyazine has adrenolytic, anticholinergic, and extrapyramidal effects .
    Pericyazine
  • HY-145577
    Lafadofensine

    		Others Neurological Disease
    Lafadofensine is the monoamines reuptake inhibitor. Lafadofensine has th sufficient effects after short-term administration (extracted from patent WO2006121218A1, compound 1) .
    Lafadofensine
  • HY-113075S
    1,5-Anhydrosorbitol-13C

    		Isotope-Labeled Compounds Endogenous Metabolite Metabolic Disease
    1,5-Anhydrosorbitol- 13C is the 13C labeled 1,5-Anhydrosorbitol. 1,5-Anhydrosorbitol is a short-term marker for glycemic cont[1][2].
    1,5-Anhydrosorbitol-13C
  • HY-N9911
    1,5-Anhydro-D-mannitol

    		Others Metabolic Disease
    1,5-Anhydro-D-mannitol is the analogue of 1,5-Anhydrosorbitol (HY-113075), and can be used as an experimental control. 1,5-Anhydrosorbitol is a short-term marker for glycemic control.
    1,5-Anhydro-D-mannitol
  • HY-D1005A22
    Poloxamer 338 (F108)

    PEG-PPG-PEG, 14600 (Averag)

    		 Biochemical Assay Reagents Others
    Poloxamer 338 F108 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 14600. Poloxamer 338 F108 reduces the aggregation of red blood cells, inhibits proliferation of human lymphocyte cell IIBR1. Poloxamer 338 F108 exhibits short-term and subchronic toxicity in rats .
    Poloxamer 338 (F108)
  • HY-113469A
    Cyclic GMP sodium
    1 Publications Verification

    		 Endogenous Metabolite Inflammation/Immunology
    Cyclic GMP sodium (cGMP) is an important regulator of short-term changes in smooth muscle tone and longer-term responses to chronic drug research or proliferative signals, it is in response to atrial natriuretic peptide (ANP) or nitric oxide (NO). Cyclic GMP sodium interacts with cation channels to regulate ion transport or activate the cyclic GMP-dependent protein kinase to result in protein phosphorylation .
    Cyclic GMP sodium
  • HY-155992
    WLB-89462

    		Sigma Receptor Neurological Disease
    WLB-89462 (Compound 20c) is a selective σ2 receptor ligand (Ki: 13 nM). WLB-89462 has neuroprotective activity. WLB-89462 improves short-term memory impairment induced by Aβ peptide in rats. WLB-89462 has good ADMET profile (good solubility, no CYP inhibition, good metabolic stability, high permeability, brain penetration, and high oral exposure in rodents) .
    WLB-89462
  • HY-112828
    LEI105

    		DAGL Neurological Disease Metabolic Disease Inflammation/Immunology
    LEI105 is a potent, highly selective and reversible dual diacylglycerol lipase (DAGL)-α/DAGL-β inhibitor. LEI105 reduces 2-arachidonoylglycerol levels in Neuro2A cells. LEI105 also reduces cannabinoid CB1-receptor-mediated short-term synaptic plasticity in a mouse hippocampal slice model. LEI105 is promising for research of diseases, such as obesity, related metabolic disorders and neuroinflammation .
    LEI105
  • HY-115893A
    P18IN005 hydrochloride

    		Others Cancer
    P18IN005 hydrochloride is a novel inhibitor of p18, exhibiting potent activity in negatively regulating haematopoietic stem cell (HSC) self-renewal. P18IN005 hydrochloride has been shown to be more effective than p27 in inhibiting HSC self-renewal in mouse models. P18IN005 hydrochloride promotes the expansion of functional HSCs in short-term cultures. P18IN005 hydrochloride serves as a valuable tool for dissecting the signaling pathways involved in stem cell self-renewal.
    P18IN005 hydrochloride
  • HY-D1005A10
    Poloxamer 184 (L64)

    PEG-PPG-PEG, 2900 (Averag)

    		 Biochemical Assay Reagents Bacterial Infection Inflammation/Immunology
    Poloxamer 184 L64 is block polymer of polyoxyethylene and polyoxypropylene with average molecular mass of 2900. Poloxamer 184 L64 exhibts short-term dermal toxicity characterized by slight erythema and intradermal inflammatory response. Poloxamer 184 L64 exhibits antimicrobial activity, that inihibits 60% Mycobacterium avium complex at concentration of 1 mg/mL. Poloxamer 184 L64 forms thermoreversible hydrogel, that is utilized in food additives, drug delivery carriers in cosmetics, pharmaceutical ingredients and tissue engineering .
    Poloxamer 184 (L64)
  • HY-N7091
    Atrazine
    1 Publications Verification

    		 Others Metabolic Disease Cancer
    Atrazine, a triazine herbicide, is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term .
    Atrazine
  • HY-129103
    A-412997

    		Dopamine Receptor Neurological Disease
    A-412997 is a selective Dopamine D4 agonist with Ki values of 12 and 7.9 nM for the rat and human receptors. A-412997 improves short term memory and cognitive properties in rodent models .
    A-412997
  • HY-N7091S2
    Atrazine-d5

    		Isotope-Labeled Compounds Metabolic Disease
    Atrazine-d5 is deuterium labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
    Atrazine-d5
  • HY-N7091S
    Atrazine-15N

    		Isotope-Labeled Compounds Metabolic Disease
    Atrazine- 15N is the 15N-labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
    Atrazine-15N
  • HY-N7091R
    Atrazine (Standard)

    		Others Metabolic Disease
    Atrazine (Standard) is the analytical standard of Atrazine. This product is intended for research and analytical applications. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term .
    Atrazine (Standard)
  • HY-A0259
    Floctafenine

    		COX Inflammation/Immunology
    Floctafenine, a nonsteroidal anti-inflammatory agent (NSAID), acts as an effective analgesic agent . Floctafenine is an inhibitor of COX-1 and COX-2 activities in vitro,showing a slightly higher potency towards COX-I. Floctafenine is used for the research of short term pain research .
    Floctafenine
  • HY-N7091S1
    Atrazine-13C3,15N3

    		Isotope-Labeled Compounds Metabolic Disease
    Atrazine- 13C3, 15N3 is the 13C-labeled and 15N-labeled Atrazine. Atrazine is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term[1].
    Atrazine-13C3,15N3
  • HY-B1435A
    Moxisylyte

    Thymoxamine

    		 Others Neurological Disease
    Moxisylyte (Thymoxamine) is an alpha 1-selective antagonist with activity that improves bladder emptying. Moxisylyte is used to suppress urinary difficulties in patients with multiple system atrophy (MSA) by blocking alpha 1-adrenergic receptors to reduce the amount of residual urine after urination. Moxisylyte is also used to suppress erectile dysfunction and can improve blood circulation problems caused by Raynaud's syndrome in the short term. In addition, Moxisylyte can be applied topically to the eye to reverse the mydriasis caused by phenylephrine and other sympathetic stimulants .
    Moxisylyte
  • HY-134611
    (2-Hydroxyethoxy)acetic acid

    β-hydroxyethoxyacetic acid; HEAA

    		 Drug Metabolite Others
    (2-Hydroxyethoxy)acetic acid (β-hydroxyethoxyacetic acid) is the main urinary metabolite of 1,4-Dioxane. (2-Hydroxyethoxy)acetic acid is a reliable and sensitive shortterm biomarker in urine .
    (2-Hydroxyethoxy)acetic acid

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