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thiol-groups

" in MedChemExpress (MCE) Product Catalog:

36

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12

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7

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-135233
    N-Succinimidyl-S-acetylthioacetate

    SATA

    		 Biochemical Assay Reagents Others
    N-Succinimidyl S-acetylthioacetate (SATA), a protein modification agent, introduces thiol-groups into protein molecules. N-Succinimidyl S-acetylthioacetate adds sulfhydryl groups to proteins and other amine-containing molecules in a protected form .
    N-Succinimidyl-S-acetylthioacetate
  • HY-15915
    DTNB
    5+ Cited Publications

    Ellman’s Reagent

    		 Biochemical Assay Reagents Others
    DTNB (Ellman’s Reagent) is a chemical used to quantify the number or concentration of thiol groups .
    DTNB
  • HY-W736950A
    H-L-Cys(MDNPE)-OH hydrochloride

    		Amino Acid Derivatives Others
    H-L-Cys(MDNPE)-OH hydrochloride is a cysteine ​​derivative with a short peptide sequence attached to the thiol group of cysteine.
    H-L-Cys(MDNPE)-OH hydrochloride
  • HY-130080
    DM3

    Maytansinoid DM3

    		 ADC Cytotoxin Microtubule/Tubulin Cancer
    DM3 (Maytansinoid DM3) is a maytansine analog bearing disulfide or thiol groups and a tubulin inhibitor, and is a cytotoxic moiety of antibody-drug conjugates (ADCs) .
    DM3
  • HY-136386
    N-Acetyl-D-cysteine
    2 Publications Verification

    		 Reactive Oxygen Species Others
    N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
    N-Acetyl-D-cysteine
  • HY-162159
    Ac-Cys-NHMe

    		Others Others
    Ac-Cys-NHMe is a Cys dipeptide with thiol group .
    Ac-Cys-NHMe
  • HY-D1526
    N-(4-Anilino-1-naphthyl)maleimide

    		Fluorescent Dye Others
    N-(4-Anilino-1-naphthyl)maleimide is a fluorescent probe that can be used to detect thiol groups in proteins. N-(4-Anilino-1-naphthyl)maleimide reacts with thiol groups and immediately produces a stable fluorescent compound with the λex=355 nm, λem=448 nm .
    N-(4-Anilino-1-naphthyl)maleimide
  • HY-134428
    Arachidonoyl coenzyme A lithium

    		Endogenous Metabolite Metabolic Disease
    Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .
    Arachidonoyl coenzyme A lithium
  • HY-W441004
    DSPE-Thiol

    		Liposome Others
    DSPE-Thiol is a phophalipid capped with thiol group. The thiol capped head can selectively react with maleimide. DSPE-Thiol can also be used for the preparation of phospholipid dimers .
    DSPE-Thiol
  • HY-D2498
    Cy7 maleimide

    		Fluorescent Dye Others
    Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .
    Cy7 maleimide
  • HY-156377
    Biotin-PEG7-Maleimide

    		Drug-Linker Conjugates for ADC Cancer
    Biotin-PEG7-Maleimide is a biotinylation reagent that reacts with thiol groups (SH). Biotin-PEG7-Maleimide can be used as Drug-Linker Conjugates for ADCs .
    Biotin-PEG7-Maleimide
  • HY-P10533
    Cysteine peptide

    		Biochemical Assay Reagents Others
    Cysteine ​​peptide is a heptapeptide containing a cysteine ​​residue whose thiol group makes it susceptible to a range of oxidative modifications. Cysteine ​​peptide is used to detect the skin sensitization potential of chemicals including cosmetic ingredients .
    Cysteine peptide
  • HY-D2488
    Sulfo Cy5.5-maleimide

    		Fluorescent Dye Others
    Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.
    Sulfo Cy5.5-maleimide
  • HY-W590555
    Thiol-PEG-DMG, MW 2000

    		Liposome Cancer
    Thiol-PEG-DMG, MW 2000 is a phospholipid polyPEG which can be used to prepare liposomes or nanoparticles. The terminal thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc.
    Thiol-PEG-DMG, MW 2000
  • HY-E70264
    16:0 Coenzyme A triammonium

    		Endogenous Metabolite Metabolic Disease
    16:0 Coenzyme A triammonium is palmitoyl-CoA, which can serve as a reaction substrate to transfer the palmitoyl group to the free thiol group of the target protein through palmitoylation catalyzed by protein acyl transferases (PATs) .
    16:0 Coenzyme A triammonium
  • HY-D1390A
    Sulfo-Cy5-Mal

    		Fluorescent Dye Others
    Sulfo-Cy5-Mal is a fluorescent dye with the form of active ester that reacts with thiol groups in proteins to form stable conjugates. Sulfo-Cy5-Mal that can be used to label protein .
    Sulfo-Cy5-Mal
  • HY-D2104
    TAMRA-PEG7-Maleimide

    		Fluorescent Dye Others
    TAMRA-PEG7-Maleimide is a dye derivative of TAMRA (HY-135640) containing 7 PEG units. TAMRA-PEG7-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
    TAMRA-PEG7-Maleimide
  • HY-W440896
    DSPE-PEG-SH, MW 2000

    		Liposome Others
    DSPE-PEG-SH, MW 2000 is a pegylated phospholipid with thiol group which is reactive with maleimide to form a covalent thioether linkage. The amphiphatic polymer can form lipid bilayer in aqueous solution and be used to encapsulate agents for drug delivery system, such as mRNA vaccine.
    DSPE-PEG-SH, MW 2000
  • HY-W190932
    TAMRA-PEG2-Maleimide

    		Fluorescent Dye Others
    TAMRA-PEG2-Maleimide is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG2-Maleimide contains a maleimide group that can react with a thiol group to form a covalent bond.
    TAMRA-PEG2-Maleimide
  • HY-168938
    Poly(ethylene glycol) methyl ether maleimide (Mn 2000)

    		Biochemical Assay Reagents Others
    Poly(ethylene glycol) methyl ether maleimide (Mn 2000) is a polyethylene glycol containing Maleimide (HY-W007324). Due to the Maleimide functional group, Poly(ethylene glycol) methyl ether maleimide (Mn 2000) can be used to conjugate biomolecules containing thiol groups.
    Poly(ethylene glycol) methyl ether maleimide (Mn 2000)
  • HY-136386R
    N-Acetyl-D-cysteine (Standard)

    		Reactive Oxygen Species Others
    N-Acetyl-D-cysteine (Standard) is the analytical standard of N-Acetyl-D-cysteine. This product is intended for research and analytical applications. N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
    N-Acetyl-D-cysteine (Standard)
  • HY-D2150
    AF 430 maleimide

    		Fluorescent Dye Others
    AF 430 maleimide is a derivative of the yellow fluorescent dye AF 430. AF430 has an excitation wavelength of 425 nm and an emission wavelength of 542 nm. AF 430 maleimide contains maleimide groups that react with thiol groups to form covalent bonds. To achieve specific coupling of dye labels and biomolecules .
    AF 430 maleimide
  • HY-W800805
    DOPE-Mal

    		Liposome Cancer
    DOPE-Mal is a synthetic analog of naturally-occurring PE containing 18:1 fatty acids at the sn-1 and sn-2 positions with a terminal maliemide group. The maleimide group will react with a thiol group to form a covalent bond. The hydrophilic PEG spacer increases solubility in aqueous media.
    DOPE-Mal
  • HY-157920
    Biotin-PE-maleimide

    N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine

    		 Biochemical Assay Reagents Others
    Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .
    Biotin-PE-maleimide
  • HY-E70254
    Tricosanoyl-CoA triammonium

    		Others Others
    Tricosanoyl-CoA triammonium is a very long-chain fatty acyl-CoA that results from the formal condensation of the thiol group of coenzyme A (HY-128851) with the carboxy group of tricosanoic acid (HY-W009081). Tricosanoyl-CoA is functionally related to a tricosanoic acid. Tricosanoyl-CoA is a conjugate acid of a tricosanoyl-CoA(4-).
    Tricosanoyl-CoA triammonium
  • HY-D1654
    BDP 581/591 maleimide

    		Fluorescent Dye Others
    BDP 581/591 maleimide is a linker of the BDP 581/591 dye. It has a long fluorescence lifetime and can be used for fluorescence polarization assays. The maleimide group can react with thiol groups to form thioester bonds between pH 6.5 to 7.5, for the labeling of sulfhydryl groups of proteins and peptides.
    BDP 581/591 maleimide
  • HY-137541
    2-Nitro-5-thiocyanatobenzoic acid

    NTCB

    		 Biochemical Assay Reagents Others
    2-Nitro-5-thiocyanatobenzoic acid (NTCB) is a highly reactive reagent that transfers its cyano group rapidly to a nucleophilic thiolate. 2-Nitro-5-thiocyanatobenzoic acid has been proposed as a reagent for converting thiol groups in proteins into their S-cyano derivatives .
    2-Nitro-5-thiocyanatobenzoic acid
  • HY-156391A
    (R)-TCO4-PEG2-Maleimide

    		PROTAC Linkers Cancer
    TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
    (R)-TCO4-PEG2-Maleimide
  • HY-156391
    TCO4-PEG2-Maleimide

    		PROTAC Linkers Cancer
    TCO4-PEG2-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG2-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
    TCO4-PEG2-Maleimide
  • HY-156392
    TCO4-PEG7-Maleimide

    		PROTAC Linkers Cancer
    TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
    TCO4-PEG7-Maleimide
  • HY-W872575A
    (R)-TCO4-PEG3-Maleimide

    		PROTAC Linkers Cancer
    TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
    (R)-TCO4-PEG3-Maleimide
  • HY-W872575
    TCO4-PEG3-Maleimide

    		PROTAC Linkers Cancer
    TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
    TCO4-PEG3-Maleimide
  • HY-D1363
    BDP R6G maleimide

    		Fluorescent Dye Others
    BDP R6G maleimide is a borodipyrromethane fluorophore with absorption and emission wavelengths similar to those of R6G rhodamine. Sulfhydryl labelling is a common protein modification where the cysteine residues in the protein allow more site-specific labelling than the NHS ester of the amine group. BDP R6G maleimide is a thiol reactive dye that reacts with thiol groups to form thioester bonds .
    BDP R6G maleimide
  • HY-D2091
    PE-VF647 Maleimide

    		Fluorescent Dye Others
    PE-VF647 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. PE-VF647 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 665 nm.
    PE-VF647 Maleimide
  • HY-D2093
    PE-VF750 Maleimide

    		Fluorescent Dye Others
    PE-VF750 Maleimide is a thiol-reactive double-dye dye that contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/777 nm. PE-VF750 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 777 nm.
    PE-VF750 Maleimide
  • HY-D2092
    PE-VF680 Maleimide

    		Fluorescent Dye Others
    PE-VF680 Maleimide is a double-dye dye that can undergo thiol reaction. It contains maleimide groups that can react with thiol groups to form covalent bonds. Ex/Em=495-566/701 nm. PE-VF680 Maleimide contains two dyes, PE and VF, with excitation wavelengths (Ex) of 495 nm and 566 nm, respectively. PE-VF594 Maleimide has an emission wavelength (Em) of 701 nm.
    PE-VF680 Maleimide