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tissue-type plasminogen activator

" in MedChemExpress (MCE) Product Catalog:

By Targets:	PAI-1 (1) Ser/Thr Protease (1)
By Research Areas:	Cancer (1)

2

Inhibitors & Agonists

1

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3

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1

Antibodies

Targets Recommended: C-type Lectin-like Receptors (CTLRs) PAI-1 Scavenger Receptor Class B type I (SR-BI） MALT1 PCSK9

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

UK122	Ser/Thr Protease	Cancer
UK122 is a potent and selective *urokinase-type plasminogen* activator (uPA) inhibitor with an IC₅₀** of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC₅₀>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion .

D-Val-Leu-Arg-pNA	PAI-1	Others
D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin .

Cat. No.	Product Name	Target	Research Area

D-Val-Leu-Arg-pNA	PAI-1	Others
D-Val-Leu-Arg-pNA is a glandular kininoreleasing enzyme substrate that also acts as a substrate for tissue-type plasminogen activator (t-PA) with no apparent affinity for fibrin .

Species:	Human (1) Mouse (2)
Tag:	His (1) Tag Free (1) Fc (1)
Source:	HEK293 (3)

Cat. No.	Compare	Product Name	Species	Source

	T-PA Protein, Mouse (HEK293, Fc) tissue-type plasminogen activator; t-PA; Plat	Mouse	HEK293
	The T-PA protein converts the inactive plasminogen to active plasmin by hydrolyzing a single Arg-Val bond.This conversion regulates plasmin-mediated proteolysis and is involved in tissue remodeling, degradation, and cell migration.T-PA also contributes to the prevention of polyspermy during oocyte activation by participating in the cortical granule reaction.T-PA Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived T-PA protein, expressed by HEK293 , with N-hFc labeled tag.

	T-PA Protein, Mouse (HEK293, His) tissue-type plasminogen activator; t-PA; Plat	Mouse	HEK293
	The T-PA protein converts the inactive plasminogen to active plasmin by hydrolyzing a single Arg-Val bond.This conversion regulates plasmin-mediated proteolysis and is involved in tissue remodeling, degradation, and cell migration.T-PA also contributes to the prevention of polyspermy during oocyte activation by participating in the cortical granule reaction.T-PA Protein, Mouse (HEK293, His) is the recombinant mouse-derived T-PA protein, expressed by HEK293 , with C-His labeled tag.

	T-PA Protein, Human (HEK293) T-PA; TPA; t-plasminogen activator; tissue plasminogen activator	Human	HEK293
	The T-PA protein encoded by this gene is a secreted serine protease that converts plasminogen into plasmin, a key enzyme involved in tissue remodeling and cell migration. The proteolytic process produces heavy and light chains, forming heterodimeric enzymes. T-PA Protein, Human (HEK293) is the recombinant human-derived T-PA protein, expressed by HEK293 , with tag free. The total length of T-PA Protein, Human (HEK293) is 252 a.a., with molecular weight of ~35 kDa.

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	Tissue Type Plasminogen Activator Antibody (YA3206) TPA; T-PA; TPA1; PLAT; tissue plasminogen activator	WB, IHC-P	Human, Mouse, Rat
	Tissue Type Plasminogen Activator Antibody (YA3206) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA3206), targeting Tissue Type Plasminogen Activator, with a predicted molecular weight of 63 kDa (observed band size: 63 kDa). Tissue Type Plasminogen Activator Antibody (YA3206) can be used for WB, IHC-P experiment in human, mouse, rat background.

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