2. Others GPCR/G Protein
  3. Isotope-Labeled Compounds Prostaglandin Receptor
  4. Selexipag-d7

Selexipag-d7 is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor)[1][2].

For research use only. We do not sell to patients.

Selexipag-d<sub>7</sub> Chemical Structure

Selexipag-d7 Chemical Structure

CAS No. : 1265295-21-3

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1 mg USD 690 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Selexipag-d7:

Selexipag-d7 Related Antibodies

Top Publications Citing Use of Products

View All Prostaglandin Receptor Isoform Specific Products:

View All Isoforms
DP EP FP IP TXA2/TP TXB2

  • Biological Activity

  • Purity & Documentation

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Description

Selexipag-d7 is the deuterium labeled Selexipag. Selexipag (NS-304) is an orally available and potent agonist for the Prostacyclin (PGI2) receptor (IP receptor)[1][2].

IC50 & Target

IP

 

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Selexipag-d7 Related Antibodies
Molecular Weight

503.66

Formula

C26H25D7N4O4S
CAS No.
Unlabeled CAS

475086-01-2
Appearance

Solid

Color

White to off-white

SMILES

CS(NC(COCCCCN(C1=CN=C(C2=CC=CC=C2)C(C3=CC=CC=C3)=N1)C(C([2H])([2H])[2H])([2H])C([2H])([2H])[2H])=O)(=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 50 mg/mL (99.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 50 mg/mL (99.27 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.9855 mL 9.9273 mL 19.8547 mL
5 mM 0.3971 mL 1.9855 mL 3.9709 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 1.9855 mL 9.9273 mL 19.8547 mL 49.6367 mL
5 mM 0.3971 mL 1.9855 mL 3.9709 mL 9.9273 mL
10 mM 0.1985 mL 0.9927 mL 1.9855 mL 4.9637 mL
15 mM 0.1324 mL 0.6618 mL 1.3236 mL 3.3091 mL
20 mM 0.0993 mL 0.4964 mL 0.9927 mL 2.4818 mL
25 mM 0.0794 mL 0.3971 mL 0.7942 mL 1.9855 mL
30 mM 0.0662 mL 0.3309 mL 0.6618 mL 1.6546 mL
40 mM 0.0496 mL 0.2482 mL 0.4964 mL 1.2409 mL
50 mM 0.0397 mL 0.1985 mL 0.3971 mL 0.9927 mL
60 mM 0.0331 mL 0.1655 mL 0.3309 mL 0.8273 mL
80 mM 0.0248 mL 0.1241 mL 0.2482 mL 0.6205 mL
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Selexipag-d7 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Selexipag-d71265295-21-3Isotope-Labeled CompoundsProstaglandin ReceptorInhibitorinhibitorinhibit

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