2. MAPK/ERK Pathway Stem Cell/Wnt
  3. ERK
  4. Serum thymic factor acetate

Serum thymic factor acetate  (Synonyms: Thymulin acetate; Thymic factor acetate)

Cat. No.: HY-P3206A
Handling Instructions

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Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Serum thymic factor acetate Chemical Structure

Serum thymic factor acetate Chemical Structure

CAS No. : 125117-65-9

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Other Forms of Serum thymic factor acetate:

Serum thymic factor acetate Related Antibodies

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Description

Serum thymic factor acetate (Thymulin acetate) is the acetate salt form of Serum thymic factor (HY-P3206). Serum thymic factor acetate is a zinc-dependent immunomodulatory peptide hormone, which can be produced by the thymic epithelial cells. Serum thymic factor acetate stimulates the release of hormones from the pituitary gland, exhibits hypophysiotropic activity. Serum thymic factor acetate protects rats from Cephaloridine (HY-B2072)-induced nephrotoxicity by inhibiting ERK activation. Serum thymic factor acetate exhibits anti-diabetic, anti-inflammatory and analgesic effects. Serum thymic factor acetate can be used in research about endocrine, reproductive, neurodegenerative and inflammatory diseases[1][2][3][4].

Molecular Weight

918.91

Formula

C35H58N12O17
CAS No.
Appearance

Solid

Sequence

{Pyr}-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
Sequence Shortening

{Pyr}-AKSQGGSN
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (108.82 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.0882 mL 5.4412 mL 10.8825 mL
5 mM 0.2176 mL 1.0882 mL 2.1765 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.0882 mL 5.4412 mL 10.8825 mL 27.2061 mL
5 mM 0.2176 mL 1.0882 mL 2.1765 mL 5.4412 mL
10 mM 0.1088 mL 0.5441 mL 1.0882 mL 2.7206 mL
15 mM 0.0725 mL 0.3627 mL 0.7255 mL 1.8137 mL
20 mM 0.0544 mL 0.2721 mL 0.5441 mL 1.3603 mL
25 mM 0.0435 mL 0.2176 mL 0.4353 mL 1.0882 mL
30 mM 0.0363 mL 0.1814 mL 0.3627 mL 0.9069 mL
40 mM 0.0272 mL 0.1360 mL 0.2721 mL 0.6802 mL
50 mM 0.0218 mL 0.1088 mL 0.2176 mL 0.5441 mL
60 mM 0.0181 mL 0.0907 mL 0.1814 mL 0.4534 mL
80 mM 0.0136 mL 0.0680 mL 0.1360 mL 0.3401 mL
100 mM 0.0109 mL 0.0544 mL 0.1088 mL 0.2721 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Serum thymic factor acetate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Serum thymic factor125117-65-9ThymulinThymic factorERKExtracellular signal regulated kinasesdiabetesmyocarditisinflammationEAEanalgesichyperalgesiaInhibitorinhibitorinhibit

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