SHP504

Cat. No.: HY-125259: FAQs
Data Sheet Handling Instructions

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SHP504 is a SHP2 phosphatase inhibitor, with an IC₅₀ of 21 μM for SHP2^1–525.

For research use only. We do not sell to patients.

SHP504 Chemical Structure

CAS No. : 2222280-83-1

Size	Stock
5 mg	Get quote	Estimated Time of Arrival: December 31
10 mg	Get quote	Estimated Time of Arrival: December 31
50 mg	Get quote	Estimated Time of Arrival: December 31
100 mg	Get quote	Estimated Time of Arrival: December 31

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Description	SHP504 is a SHP2 phosphatase inhibitor, with an IC₅₀ of 21 μM for SHP2^1–525^[1].
Molecular Weight	446.84
Formula	C₂₃H₁₅ClN₄O₄
CAS No.	2222280-83-1
SMILES	O=C(O)C1=CC=C(O)C(C2=NN=C(N3CC4=CC=CC=C4Cl)N2C5=C(C=CC=C5)C3=O)=C1
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Michelle Fodor, et al. Dual Allosteric Inhibition of SHP2 Phosphatase. ACS Chem Biol. 2018 Mar 16;13(3):647-656. [Content Brief]

SHP504 Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SHP5042222280-83-1SHP 504SHP-504SHP2PhosphataseSrc homology phosphatase 2PTPN11PTPN11,Inhibitorinhibitorinhibit

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SHP504

SHP504 Related Antibodies

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