1. Antibody-drug Conjugate/ADC Related
  2. ADC Cytotoxin
  3. SJG-136 intermediate-1

SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA.

For research use only. We do not sell to patients.

SJG-136 intermediate-1 Chemical Structure

SJG-136 intermediate-1 Chemical Structure

CAS No. : 232931-64-5

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Description

SJG-136 intermediate-1 (compound 19) is an intermediate for synthesizing SJG-136. SJG-136 is a DNA cross-linking agent, with an XL50 of 45 nM for pBR322 DNA[1].

Molecular Weight

760.79

Formula

C39H44N4O12

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C=CCOC(N1C2=CC(OCCCOC3=C(OC)C=C(C(N4[C@](CC(C4)=C)([H])[C@@H](N5C(OCC=C)=O)O)=O)C5=C3)=C(OC)C=C2C(N6[C@](CC(C6)=C)([H])[C@@H]1O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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SJG-136 intermediate-1 Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
SJG-136 intermediate-1
Cat. No.:
HY-402091
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