2. Anti-infection
  3. Fungal
  4. Stictic acid

Stictic acid is a secondary metabolite that can be isolated from the lichen Lobaria pulmonaria (L.) Hoffm. Stictic acid inhibits growth of human colon adenocarcinoma HT-29 cells (IC50: 29.29 μg/mL).

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Stictic acid Chemical Structure

Stictic acid Chemical Structure

CAS No. : 549-06-4

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500 μg In-stock

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Based on 1 publication(s) in Google Scholar

Stictic acid Related Antibodies

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Description

Stictic acid is a secondary metabolite that can be isolated from the lichen Lobaria pulmonaria (L.) Hoffm. Stictic acid inhibits growth of human colon adenocarcinoma HT-29 cells (IC50: 29.29 μg/mL)[1].

Cellular Effect
Cell Line Type Value Description References
HeLa IC50
> 10 μM
Compound: 1
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 24 hrs by WST-1 assay
[PMID: 24725159]
HeLa IC50
> 10 μM
Compound: 1
Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay
Cytotoxicity against human HeLa cells after 48 hrs by WST-1 assay
[PMID: 24725159]
Hepatocyte IC50
≤ 13 μM
Compound: 3
Cytotoxicity against rat hepatocytes assessed as induction intracellular LDH release incubated for 8 to 24 hrs
Cytotoxicity against rat hepatocytes assessed as induction intracellular LDH release incubated for 8 to 24 hrs
[PMID: 33290062]
HL-60 IC50
> 10 μM
Compound: 1
Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
Cytotoxicity against human HL60 cells after 24 hrs by WST-1 assay
[PMID: 24725159]
HL-60 IC50
> 10 μM
Compound: 1
Cytotoxicity against human HL60 cells after 48 hrs by WST-1 assay
Cytotoxicity against human HL60 cells after 48 hrs by WST-1 assay
[PMID: 24725159]
Vero IC50
> 150 μM
Compound: 1
Cytotoxicity against African green monkey Vero cells after 24 hrs by Alamar Blue assay
Cytotoxicity against African green monkey Vero cells after 24 hrs by Alamar Blue assay
[PMID: 24725159]
Vero IC50
> 150 μM
Compound: 1
Cytotoxicity against African green monkey Vero cells after 48 hrs by Alamar Blue assay
Cytotoxicity against African green monkey Vero cells after 48 hrs by Alamar Blue assay
[PMID: 24725159]
Molecular Weight

386.31

Formula

C19H14O9
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=CC1=C(OC(C2=C(C(OC2O)=O)C(O)=C3C)=C3OC4=O)C4=C(C)C=C1OC
Structure Classification
Initial Source

Lobaria pulmonaria
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 11 mg/mL (28.47 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5886 mL 12.9430 mL 25.8859 mL
5 mM 0.5177 mL 2.5886 mL 5.1772 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.5%

SDS (418 KB)

COA (258 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5886 mL 12.9430 mL 25.8859 mL 64.7149 mL
5 mM 0.5177 mL 2.5886 mL 5.1772 mL 12.9430 mL
10 mM 0.2589 mL 1.2943 mL 2.5886 mL 6.4715 mL
15 mM 0.1726 mL 0.8629 mL 1.7257 mL 4.3143 mL
20 mM 0.1294 mL 0.6471 mL 1.2943 mL 3.2357 mL
25 mM 0.1035 mL 0.5177 mL 1.0354 mL 2.5886 mL
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Stictic acid Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Stictic acid549-06-4Fungalcolon adenocarcinoma,cancerInhibitorinhibitorinhibit

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