2. Apoptosis
  3. DAPK
  4. STK17A/B-IN-1 hydrochloride

STK17A/B-IN-1 hydrochloride is an orally active, potent and selective STK17A/B inhibitor with an IC50 value of 23 nM for STK17A. STK17A/B-IN-1 hydrochloride can be used in tumor research.

For research use only. We do not sell to patients.

STK17A/B-IN-1 hydrochloride Chemical Structure

STK17A/B-IN-1 hydrochloride Chemical Structure

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 517 In-stock
Solution
10 mM * 1 mL in DMSO USD 517 In-stock
Solid
5 mg USD 480 In-stock
10 mg USD 771 In-stock
25 mg USD 1543 In-stock
50 mg USD 2392 In-stock
100 mg USD 3589 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Other Forms of STK17A/B-IN-1 hydrochloride:

STK17A/B-IN-1 hydrochloride Related Antibodies

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Description

STK17A/B-IN-1 hydrochloride is an orally active, potent and selective STK17A/B inhibitor with an IC50 value of 23 nM for STK17A. STK17A/B-IN-1 hydrochloride can be used in tumor research[1].

Molecular Weight

490.00

Formula

C26H28ClN7O
Appearance

Solid

SMILES

O=C(C1=CC=C(NC2=NC=CC(C3=CC4=C(N=C(N5CCCC5)N=C4)C=C3)=N2)C=C1)NC(C)C.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 14.29 mg/mL (29.16 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0408 mL 10.2041 mL 20.4082 mL
5 mM 0.4082 mL 2.0408 mL 4.0816 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0408 mL 10.2041 mL 20.4082 mL 51.0204 mL
5 mM 0.4082 mL 2.0408 mL 4.0816 mL 10.2041 mL
10 mM 0.2041 mL 1.0204 mL 2.0408 mL 5.1020 mL
15 mM 0.1361 mL 0.6803 mL 1.3605 mL 3.4014 mL
20 mM 0.1020 mL 0.5102 mL 1.0204 mL 2.5510 mL
25 mM 0.0816 mL 0.4082 mL 0.8163 mL 2.0408 mL
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STK17A/B-IN-1 hydrochloride Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

STK17A/B-IN-1DAPKDeath associated protein kinaseInhibitorinhibitorinhibit

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