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  4. SU-4029 dihydrochloride

Su-4029 is an agent that interacts with alpha receptors. It negates the blockade of norepinephrine by the reversible adrenergic blocker phentolamine but not by the irreversible blocker Dibenamine, suggesting Su-4029 acts at the same site as these blockers. Su-4029 pretreatment results in three categories of responses to pressor phenylalkylamines: irreversible blockade of amines with no or only p-hydroxylation, reversible blockade of amines with beta-carbon hydroxylation, and no blockade or augmentation of amines with m and p-hydroxylation or m or p plus beta-hydroxylation. Su-4029 may deform the alpha receptor site affected by adrenergic blocking agents.

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SU-4029 dihydrochloride Chemical Structure

SU-4029 dihydrochloride Chemical Structure

CAS No. : 3194-36-3

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SU-4029 dihydrochloride Related Antibodies

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Description

Su-4029 is an agent that interacts with alpha receptors. It negates the blockade of norepinephrine by the reversible adrenergic blocker phentolamine but not by the irreversible blocker Dibenamine, suggesting Su-4029 acts at the same site as these blockers. Su-4029 pretreatment results in three categories of responses to pressor phenylalkylamines: irreversible blockade of amines with no or only p-hydroxylation, reversible blockade of amines with beta-carbon hydroxylation, and no blockade or augmentation of amines with m and p-hydroxylation or m or p plus beta-hydroxylation. Su-4029 may deform the alpha receptor site affected by adrenergic blocking agents[1].

Molecular Weight

258.19

Formula

C9H21Cl2N3O
CAS No.
SMILES

N=C(CCN1CCCCCC1)NO.Cl.Cl
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SU-4029 dihydrochloride Related Classifications

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Keywords:

SU-40293194-36-3SU4029SU 4029OthersInhibitorinhibitorinhibit

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