1. Metabolic Enzyme/Protease
  2. Enteropeptidase
  3. Sucunamostat

Sucunamostat (SCO-792 free acid) is an L-aspartic acid enteropeptidase inhibitor.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (Sucunamostat hydrochloride) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

Sucunamostat Chemical Structure

Sucunamostat Chemical Structure

CAS No. : 1802888-04-5

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Description

Sucunamostat (SCO-792 free acid) is an L-aspartic acid enteropeptidase inhibitor[1].

Molecular Weight

470.43

Formula

C22H22N4O8

CAS No.
SMILES

OC(C[C@@H](C(O)=O)NC(C[C@H]1C2=CC=C(OC(C3=CC=C(C=C3)NC(N)=N)=O)C=C2OC1)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 62.5 mg/mL (132.86 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1257 mL 10.6286 mL 21.2571 mL
5 mM 0.4251 mL 2.1257 mL 4.2514 mL
View the Complete Stock Solution Preparation Table
  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

V1

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1257 mL 10.6286 mL 21.2571 mL 53.1429 mL
5 mM 0.4251 mL 2.1257 mL 4.2514 mL 10.6286 mL
10 mM 0.2126 mL 1.0629 mL 2.1257 mL 5.3143 mL
15 mM 0.1417 mL 0.7086 mL 1.4171 mL 3.5429 mL
20 mM 0.1063 mL 0.5314 mL 1.0629 mL 2.6571 mL
25 mM 0.0850 mL 0.4251 mL 0.8503 mL 2.1257 mL
30 mM 0.0709 mL 0.3543 mL 0.7086 mL 1.7714 mL
40 mM 0.0531 mL 0.2657 mL 0.5314 mL 1.3286 mL
50 mM 0.0425 mL 0.2126 mL 0.4251 mL 1.0629 mL
60 mM 0.0354 mL 0.1771 mL 0.3543 mL 0.8857 mL
80 mM 0.0266 mL 0.1329 mL 0.2657 mL 0.6643 mL
100 mM 0.0213 mL 0.1063 mL 0.2126 mL 0.5314 mL
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Sucunamostat Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Sucunamostat
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HY-132841
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