1. Protein Tyrosine Kinase/RTK Cell Cycle/DNA Damage Autophagy Apoptosis
  2. PDGFR VEGFR IRE1 Mitophagy Autophagy Apoptosis
  3. Sunitinib (Malate) (Standard)

Sunitinib (Malate) (Standard) 

Cat. No.: HY-10255R Purity: ≥98%
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Sunitinib (Malate) (Standard) is the analytical standard of Sunitinib (Malate). This product is intended for research and analytical applications. Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

For research use only. We do not sell to patients.

Sunitinib (Malate) (Standard) Chemical Structure

Sunitinib (Malate) (Standard) Chemical Structure

CAS No. : 341031-54-7

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Description

Sunitinib (Malate) (Standard) is the analytical standard of Sunitinib (Malate). This product is intended for research and analytical applications. Sunitinib Malate (SU 11248 Malate) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 80 nM and 2 nM for VEGFR2 and PDGFRβ, respectively. Sunitinib Malate, an ATP-competitive inhibitor, effectively inhibits autophosphorylation of Ire1α by inhibiting autophosphorylation and consequent RNase activation.

Molecular Weight

532.56

Formula

C26H33FN4O7

CAS No.
SMILES

O=C(NCCN(CC)CC)C1=C(NC(/C=C2C(NC3=C\2C=C(C=C3)F)=O)=C1C)C.O=C([C@H](CC(O)=O)O)O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Sunitinib (Malate) (Standard)
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