2. Anti-infection
  3. Bacterial
  4. Tachyplesin I

Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Tachyplesin I Chemical Structure

Tachyplesin I Chemical Structure

CAS No. : 118231-04-2

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Based on 1 publication(s) in Google Scholar

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Description

Tachyplesin I is a β-hairpin antimicrobial peptide that contains 17 amino acid residues. Tachyplesin I exhibits cytotoxic properties against various human tumor cell lines acting primarily by impairing the integrity of the outer cell membrane[1].

Molecular Weight

2263.74

Formula

C99H151N35O19S4
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Lys-Trp-Cys-Phe-Arg-Val-Cys-Tyr-Arg-Gly-Ile-Cys-Tyr-Arg-Arg-Cys-Arg-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12)
Sequence Shortening

KWCFRVCYRGICYRRCR-NH2 (Disulfide bridge:Cys3-Cys16,Cys7-Cys12)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (44.17 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4417 mL 2.2087 mL 4.4175 mL
5 mM 0.0883 mL 0.4417 mL 0.8835 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4417 mL 2.2087 mL 4.4175 mL 11.0437 mL
5 mM 0.0883 mL 0.4417 mL 0.8835 mL 2.2087 mL
10 mM 0.0442 mL 0.2209 mL 0.4417 mL 1.1044 mL
15 mM 0.0294 mL 0.1472 mL 0.2945 mL 0.7362 mL
20 mM 0.0221 mL 0.1104 mL 0.2209 mL 0.5522 mL
25 mM 0.0177 mL 0.0883 mL 0.1767 mL 0.4417 mL
30 mM 0.0147 mL 0.0736 mL 0.1472 mL 0.3681 mL
40 mM 0.0110 mL 0.0552 mL 0.1104 mL 0.2761 mL
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Tachyplesin I Related Classifications

Keywords:

Tachyplesin I118231-04-2BacterialAntimicrobial Peptideβ-hairpinouter cell membraneInhibitorinhibitorinhibit

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