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  2. Isotope-Labeled Compounds
  3. Tempone-15N,d16

Tempone-15N,d16  (Synonyms: 4-Oxo-Tempo-15N,d16)

Cat. No.: HY-129242S
Handling Instructions

Tempone-15N,d16 is the deuterium and 15N labeled Tempone[1].

For research use only. We do not sell to patients.

Tempone-<sup>15</sup>N,d<sub>16</sub> Chemical Structure

Tempone-15N,d16 Chemical Structure

CAS No. : 80404-14-4

Size Price Stock Quantity
5 mg USD 175 In-stock
10 mg USD 280 In-stock
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Description

Tempone-15N,d16 is the deuterium and 15N labeled Tempone[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

187.32

Formula

15NC9D16O2

CAS No.
Unlabeled CAS

2896-70-0

Appearance

Solid

Color

Light yellow to yellow

SMILES

[O][15N]1C(C([2H])([2H])[2H])(C([2H])([2H])C(C([2H])([2H])C1(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)C([2H])([2H])[2H]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (160.15 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3385 mL 26.6923 mL 53.3846 mL
5 mM 1.0677 mL 5.3385 mL 10.6769 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 5.3385 mL 26.6923 mL 53.3846 mL 133.4615 mL
5 mM 1.0677 mL 5.3385 mL 10.6769 mL 26.6923 mL
10 mM 0.5338 mL 2.6692 mL 5.3385 mL 13.3461 mL
15 mM 0.3559 mL 1.7795 mL 3.5590 mL 8.8974 mL
20 mM 0.2669 mL 1.3346 mL 2.6692 mL 6.6731 mL
25 mM 0.2135 mL 1.0677 mL 2.1354 mL 5.3385 mL
30 mM 0.1779 mL 0.8897 mL 1.7795 mL 4.4487 mL
40 mM 0.1335 mL 0.6673 mL 1.3346 mL 3.3365 mL
50 mM 0.1068 mL 0.5338 mL 1.0677 mL 2.6692 mL
60 mM 0.0890 mL 0.4449 mL 0.8897 mL 2.2244 mL
80 mM 0.0667 mL 0.3337 mL 0.6673 mL 1.6683 mL
100 mM 0.0534 mL 0.2669 mL 0.5338 mL 1.3346 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Tempone-15N,d16
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