1. Immunology/Inflammation
  2. PSMA
  3. tert-Butyl-DCL

tert-Butyl-DCL is a small molecule PSMAM inhibitor with anticancer activity that targets prostate-specific membrane antigen (PSMA). tert-Butyl-DCL is also an effective bioimaging agent that has high selectivity and affinity, allowing it to target and highlight specific receptors on the surface of tumor cells.

For research use only. We do not sell to patients.

tert-Butyl-DCL Chemical Structure

tert-Butyl-DCL Chemical Structure

CAS No. : 1025796-31-9

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10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 63 In-stock
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100 mg USD 58 In-stock
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Description

tert-Butyl-DCL is a small molecule PSMAM inhibitor with anticancer activity that targets prostate-specific membrane antigen (PSMA). tert-Butyl-DCL is also an effective bioimaging agent that has high selectivity and affinity, allowing it to target and highlight specific receptors on the surface of tumor cells[1].

Molecular Weight

487.63

Formula

C24H45N3O7

CAS No.
Appearance

Solid-Liquid Mixture

Color

Colorless to off-white

SMILES

CC(C)(C)OC([C@H](CCCCN)NC(N[C@H](C(OC(C)(C)C)=O)CCC(OC(C)(C)C)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (205.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0507 mL 10.2537 mL 20.5074 mL
5 mM 0.4101 mL 2.0507 mL 4.1015 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation

Purity: ≥98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0507 mL 10.2537 mL 20.5074 mL 51.2684 mL
5 mM 0.4101 mL 2.0507 mL 4.1015 mL 10.2537 mL
10 mM 0.2051 mL 1.0254 mL 2.0507 mL 5.1268 mL
15 mM 0.1367 mL 0.6836 mL 1.3672 mL 3.4179 mL
20 mM 0.1025 mL 0.5127 mL 1.0254 mL 2.5634 mL
25 mM 0.0820 mL 0.4101 mL 0.8203 mL 2.0507 mL
30 mM 0.0684 mL 0.3418 mL 0.6836 mL 1.7089 mL
40 mM 0.0513 mL 0.2563 mL 0.5127 mL 1.2817 mL
50 mM 0.0410 mL 0.2051 mL 0.4101 mL 1.0254 mL
60 mM 0.0342 mL 0.1709 mL 0.3418 mL 0.8545 mL
80 mM 0.0256 mL 0.1282 mL 0.2563 mL 0.6409 mL
100 mM 0.0205 mL 0.1025 mL 0.2051 mL 0.5127 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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tert-Butyl-DCL
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