2. GPCR/G Protein Metabolic Enzyme/Protease Autophagy
  3. Adenosine Receptor Phosphodiesterase (PDE) Autophagy Endogenous Metabolite
  4. Theophylline-d6

Theophylline-d6  (Synonyms: 1,3-Dimethylxanthine-d6; Theo-24-d6)

Cat. No.: HY-B0809S Purity: 99.90%
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Theophylline-d6 is the deuterium labeled Theophylline. Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.

For research use only. We do not sell to patients.

Theophylline-d<sub>6</sub> Chemical Structure

Theophylline-d6 Chemical Structure

CAS No. : 117490-39-8

Size Price Stock Quantity
500 μg USD 120 In-stock
1 mg USD 220 In-stock
5 mg USD 704 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Theophylline-d6:

Theophylline-d6 Related Antibodies

Top Publications Citing Use of Products

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Adenosine A1 receptor (A1R) Adenosine A2A receptor (A2AR) Adenosine A2B receptor (A2BR) Adenosine A3 receptor (A3R)

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PDE1 PDE2 PDE3 PDE4 PDE5 PDE6 PDE7 PDE9 PDE10 PDE11 PDE12 PDE8 Autotaxin

  • Biological Activity

  • Purity & Documentation

  • References

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Description

Theophylline-d6 is the deuterium labeled Theophylline. Theophylline is a nonselective phosphodiesterase (PDE) inhibitor, adenosine receptor blocker, and histone deacetylase (HDAC) activator.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Theophylline-d6 Related Antibodies
Molecular Weight

186.20

Formula

C7H2D6N4O2
CAS No.
Unlabeled CAS

58-55-9
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1C([2H])([2H])[2H])N(C([2H])([2H])[2H])C2=C(N=CN2)C1=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMF : ≥ 10 mg/mL (53.71 mM)

DMSO : ≥ 10 mg/mL (53.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : ≥ 10 mg/mL (53.71 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMF : ≥ 10 mg/mL (53.71 mM)

Ethanol : ≥ 1 mg/mL (5.37 mM)

PBS (pH 7.2) : ≥ 1 mg/mL (5.37 mM)

Ethanol : ≥ 1 mg/mL (5.37 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.3706 mL 26.8528 mL 53.7057 mL
5 mM 1.0741 mL 5.3706 mL 10.7411 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / PBS (pH 7.2) / Ethanol / DMF / DMSO / DMSO / DMF 1 mM 5.3706 mL 26.8528 mL 53.7057 mL 134.2642 mL
5 mM 1.0741 mL 5.3706 mL 10.7411 mL 26.8528 mL
DMF / DMSO / DMSO / DMF 10 mM 0.5371 mL 2.6853 mL 5.3706 mL 13.4264 mL
15 mM 0.3580 mL 1.7902 mL 3.5804 mL 8.9509 mL
20 mM 0.2685 mL 1.3426 mL 2.6853 mL 6.7132 mL
25 mM 0.2148 mL 1.0741 mL 2.1482 mL 5.3706 mL
30 mM 0.1790 mL 0.8951 mL 1.7902 mL 4.4755 mL
40 mM 0.1343 mL 0.6713 mL 1.3426 mL 3.3566 mL
50 mM 0.1074 mL 0.5371 mL 1.0741 mL 2.6853 mL
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Theophylline-d6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Theophylline-d6117490-39-81,3-Dimethylxanthine-d6Theo-24-d6Adenosine ReceptorPhosphodiesterase (PDE)AutophagyEndogenous MetaboliteP1 receptorInhibitorinhibitorinhibit

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