2. Metabolic Enzyme/Protease Anti-infection
  3. Parasite Mitochondrial Metabolism
  4. Thiabendazole-d4

Thiabendazole-d4  (Synonyms: 2-(4-Thiazolyl)benzimidazole-d4)

Cat. No.: HY-B0263S Purity: 98.84%
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Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].

For research use only. We do not sell to patients.

Thiabendazole-d<sub>4</sub> Chemical Structure

Thiabendazole-d4 Chemical Structure

CAS No. : 1190007-20-5

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1 mg USD 220 In-stock
5 mg USD 650 In-stock
10 mg USD 1100 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Thiabendazole-d4:

Thiabendazole-d4 Related Antibodies

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Description

Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[75].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Thiabendazole-d4 Related Antibodies
Molecular Weight

205.27

Formula

C10H3D4N3S
CAS No.
Unlabeled CAS

148-79-8
Appearance

Solid

Color

White to off-white

SMILES

[2H]C1=C2N=C(C3=CSC=N3)NC2=C([2H])C([2H])=C1[2H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (243.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

DMSO : 50 mg/mL (243.58 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 0.1 mg/mL (0.49 mM; Need ultrasonic)

H2O : 0.1 mg/mL (0.49 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.8716 mL 24.3582 mL 48.7163 mL
5 mM 0.9743 mL 4.8716 mL 9.7433 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / DMSO 1 mM 4.8716 mL 24.3582 mL 48.7163 mL 121.7908 mL
5 mM 0.9743 mL 4.8716 mL 9.7433 mL 24.3582 mL
10 mM 0.4872 mL 2.4358 mL 4.8716 mL 12.1791 mL
15 mM 0.3248 mL 1.6239 mL 3.2478 mL 8.1194 mL
20 mM 0.2436 mL 1.2179 mL 2.4358 mL 6.0895 mL
25 mM 0.1949 mL 0.9743 mL 1.9487 mL 4.8716 mL
30 mM 0.1624 mL 0.8119 mL 1.6239 mL 4.0597 mL
40 mM 0.1218 mL 0.6090 mL 1.2179 mL 3.0448 mL
50 mM 0.0974 mL 0.4872 mL 0.9743 mL 2.4358 mL
60 mM 0.0812 mL 0.4060 mL 0.8119 mL 2.0298 mL
80 mM 0.0609 mL 0.3045 mL 0.6090 mL 1.5224 mL
100 mM 0.0487 mL 0.2436 mL 0.4872 mL 1.2179 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Thiabendazole-d4 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thiabendazole-d41190007-20-52-(4-Thiazolyl)benzimidazole-d4ParasiteMitochondrial Metabolismdeuterium labeled Thiabendazoleantifungal agentblood vesselsvascular disrupting agentanti-angiogenic therapiestumor growthInhibitorinhibitorinhibit

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